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The tumor immune microenvironment (TIME) in non-small cell lung cancer (NSCLC) histopathology contains morphological and molecular characteristics predictive of immunotherapy response. Computational quantification of TIME characteristics,…

Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the…

计算机视觉与模式识别 · 计算机科学 2019-02-01 Jason W. Wei , Laura J. Tafe , Yevgeniy A. Linnik , Louis J. Vaickus , Naofumi Tomita , Saeed Hassanpour

Accurate three-dimensional delineation of liver tumors on contrast-enhanced CT is a prerequisite for treatment planning, navigation and response assessment, yet manual contouring is slow, observer-dependent and difficult to standardise…

图像与视频处理 · 电气工程与系统科学 2025-12-09 Xuecheng Li , Weikuan Jia , Komildzhon Sharipov , Alimov Ruslan , Lutfuloev Mazbutdzhon , Ismoilov Shuhratjon , Yuanjie Zheng

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Ultrasound (US) is a critical modality for diagnosing liver fibrosis. Unfortunately, assessment is very subjective, motivating automated approaches. We introduce a principled deep convolutional neural network (CNN) workflow that…

图像与视频处理 · 电气工程与系统科学 2020-08-11 Bowen Li , Ke Yan , Dar-In Tai , Yuankai Huo , Le Lu , Jing Xiao , Adam P. Harrison

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

计算机视觉与模式识别 · 计算机科学 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Lung and Colon cancer are one of the leading causes of mortality and morbidity in adults. Histopathological diagnosis is one of the key components to discern cancer type. The aim of the present research is to propose a computer aided…

图像与视频处理 · 电气工程与系统科学 2020-09-09 Sanidhya Mangal , Aanchal Chaurasia , Ayush Khajanchi

Deep learning-based segmentation of the liver and hepatic lesions therein steadily gains relevance in clinical practice due to the increasing incidence of liver cancer each year. Whereas various network variants with overall promising…

图像与视频处理 · 电气工程与系统科学 2023-03-23 Georg Hille , Shubham Agrawal , Pavan Tummala , Christian Wybranski , Maciej Pech , Alexey Surov , Sylvia Saalfeld

Lung and colon cancer are serious worldwide health challenges that require early and precise identification to reduce mortality risks. However, diagnosis, which is mostly dependent on histopathologists' competence, presents difficulties and…

图像与视频处理 · 电气工程与系统科学 2024-05-15 Mukaffi Bin Moin , Fatema Tuj Johora Faria , Swarnajit Saha , Busra Kamal Rafa , Mohammad Shafiul Alam

Artificial intelligence (AI) holds strong potential for medical diagnostics, yet its clinical adoption is limited by a lack of interpretability and generalizability. This study introduces the Pathobiological Dictionary for Liver Cancer…

The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

计算机视觉与模式识别 · 计算机科学 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

Histopathological images (HI) encrypt resolution dependent heterogeneous textures & diverse color distribution variability, manifesting in micro-structural surface tissue convolutions. Also, inherently high coherency of cancerous cells…

计算机视觉与模式识别 · 计算机科学 2019-03-26 Sawon Pratiher , Subhankar Chattoraj

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Quantifiable image patterns associated with disease progression and treatment response are critical tools for guiding individual treatment, and for developing novel therapies. Here, we show that unsupervised machine learning can identify a…

图像与视频处理 · 电气工程与系统科学 2025-07-17 Matthias Perkonigg , Nina Bastati , Ahmed Ba-Ssalamah , Peter Mesenbrink , Alexander Goehler , Miljen Martic , Xiaofei Zhou , Michael Trauner , Georg Langs

Prostate cancer is the most prevalent cancer among men in Western countries, with 1.1 million new diagnoses every year. The gold standard for the diagnosis of prostate cancer is a pathologists' evaluation of prostate tissue. To potentially…

图像与视频处理 · 电气工程与系统科学 2020-10-23 Hans Pinckaers , Wouter Bulten , Jeroen van der Laak , Geert Litjens

Histopathologic Images (HI) are the gold standard for evaluation of some tumors. However, the analysis of such images is challenging even for experienced pathologists, resulting in problems of inter and intra observer. Besides that, the…

计算机视觉与模式识别 · 计算机科学 2019-04-18 Jonathan de Matos , Alceu de Souza Britto , Luiz E. S. Oliveira , Alessandro L. Koerich

Breast cancer is the most common cancer in the world and the second most common type of cancer that causes death in women. The timely and accurate diagnosis of breast cancer using histopathological images is crucial for patient care and…

图像与视频处理 · 电气工程与系统科学 2022-11-03 Amira Alotaibi , Tarik Alafif , Faris Alkhilaiwi , Yasser Alatawi , Hassan Althobaiti , Abdulmajeed Alrefaei , Yousef M Hawsawi , Tin Nguyen

Breast cancer is one of the most prevalent cancers worldwide and pathologists are closely involved in establishing a diagnosis. Tools to assist in making a diagnosis are required to manage the increasing workload. In this context,…

Liver cancer is a leading cause of cancer-related mortality worldwide, with its high genetic heterogeneity complicating diagnosis and treatment. This study introduces DLSOM, a deep learning framework utilizing stacked autoencoders to…

基因组学 · 定量生物学 2024-12-18 Fabio Zamio

Early diagnosis of the cancer cells is necessary for making an effective treatment plan and for the health and safety of a patient. Nowadays, doctors usually use a histological grade that pathologists determine by performing a…

计算机视觉与模式识别 · 计算机科学 2023-11-15 Varan Singh Rohila , Neeraj Lalwani , Lochan Basyal