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The visual examination of tissue biopsy sections is fundamental for cancer diagnosis, with pathologists analyzing sections at multiple magnifications to discern tumor cells and their subtypes. However, existing attention-based multiple…

计算机视觉与模式识别 · 计算机科学 2024-10-11 Olga Fourkioti , Matt De Vries , Chen Jin , Daniel C. Alexander , Chris Bakal

Atrial Fibrillation (AF) is characterized by rapid, irregular heartbeats, and can lead to fatal complications such as heart failure. The disease is divided into two sub-types based on severity, which can be automatically classified through…

计算机视觉与模式识别 · 计算机科学 2023-08-15 Weihang Dai , Xiaomeng Li , Taihui Yu , Di Zhao , Jun Shen , Kwang-Ting Cheng

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

图像与视频处理 · 电气工程与系统科学 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

Multi-instance learning (MIL) is an effective paradigm for whole-slide pathological images (WSIs) classification to handle the gigapixel resolution and slide-level label. Prevailing MIL methods primarily focus on improving the feature…

计算机视觉与模式识别 · 计算机科学 2023-03-14 Tiancheng Lin , Zhimiao Yu , Hongyu Hu , Yi Xu , Chang Wen Chen

Classical multiple instance learning (MIL) methods are often based on the identical and independent distributed assumption between instances, hence neglecting the potentially rich contextual information beyond individual entities. On the…

计算机视觉与模式识别 · 计算机科学 2022-06-20 Daniel Reisenbüchler , Sophia J. Wagner , Melanie Boxberg , Tingying Peng

Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…

计算机视觉与模式识别 · 计算机科学 2025-12-23 Jinqiu Chen , Huyan Xu

Deep learning based computer vision fails to work when labeled images are scarce. Recently, Meta learning algorithm has been confirmed as a promising way to improve the ability of learning from few images for computer vision. However,…

机器学习 · 计算机科学 2018-11-27 Yunxiao Qin , Chenxu Zhao , Zezheng Wang , Junliang Xing , Jun Wan , Zhen Lei

Lung adenocarcinoma (LUAD) is characterized by substantial genetic heterogeneity, posing challenges in identifying reliable biomarkers for improved diagnosis and treatment. Tumor Mutational Burden (TMB) has traditionally been regarded as a…

应用统计 · 统计学 2024-11-08 Shaofei Zhao , Siming Huang , Kexuan Li , Weiyu Zhou , Lingli Yang , Shige Wang

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Masked diffusion language models (MDLMs) enable parallel decoding by predicting all masked positions at each denoising step, yet existing training-free samplers usually decide which positions to commit at token-level granularity. We revisit…

机器学习 · 计算机科学 2026-05-29 Heqiang Qi , Wei Huang , Mingyuan Bai , Xiangming Meng

Dense prediction models are widely used for image segmentation. One important challenge is to sufficiently train these models to yield good generalizations for hard-to-learn pixels. A typical group of such hard-to-learn pixels are…

计算机视觉与模式识别 · 计算机科学 2019-08-07 Gozde Nur Gunesli , Cenk Sokmensuer , Cigdem Gunduz-Demir

Multimodal learning, integrating histology images and genomics, promises to enhance precision oncology with comprehensive views at microscopic and molecular levels. However, existing methods may not sufficiently model the shared or…

计算机视觉与模式识别 · 计算机科学 2024-06-12 Huahui Yi , Xiaofei Wang , Kang Li , Chao Li

Multiple Instance Learning (MIL) has been widely applied in pathology towards solving critical problems such as automating cancer diagnosis and grading, predicting patient prognosis, and therapy response. Deploying these models in a…

计算机视觉与模式识别 · 计算机科学 2022-10-18 Syed Ashar Javed , Dinkar Juyal , Harshith Padigela , Amaro Taylor-Weiner , Limin Yu , Aaditya Prakash

Advancements in deep learning are driven by training models with increasingly larger numbers of parameters, which in turn heightens the computational demands. To address this issue, Mixture-of-Depths (MoD) models have been proposed to…

计算机视觉与模式识别 · 计算机科学 2024-12-31 Advait Gadhikar , Souptik Kumar Majumdar , Niclas Popp , Piyapat Saranrittichai , Martin Rapp , Lukas Schott

Current deep learning based text classification methods are limited by their ability to achieve fast learning and generalization when the data is scarce. We address this problem by integrating a meta-learning procedure that uses the…

Quantum machine learning offers a promising new paradigm for computational biology by leveraging quantum mechanical principles to enhance cancer classification, biomarker discovery, and bioinformatics diagnostics. In this study, we apply…

基因组学 · 定量生物学 2026-04-22 Mandeep Kaur Saggi , Amandeep Singh Bhatia , Humaira Gowher , Sabre Kais

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

计算机视觉与模式识别 · 计算机科学 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Learning robust representations for physiological time-series signals continues to pose a substantial challenge in developing efficient few-shot learning applications. This difficulty is largely due to the complex pathological variations in…

机器学习 · 计算机科学 2025-12-01 Rami Zewail

Automated interpretation of ultrasound imaging of the heart (echocardiograms) could improve the detection and treatment of aortic stenosis (AS), a deadly heart disease. However, existing deep learning pipelines for assessing AS from…

计算机视觉与模式识别 · 计算机科学 2024-03-12 Zhe Huang , Xiaowei Yu , Benjamin S. Wessler , Michael C. Hughes

In-context Learning (ICL) utilizes structured demonstration-query inputs to induce few-shot learning on Language Models (LMs), which are not originally pre-trained on ICL-style data. To bridge the gap between ICL and pre-training, some…

计算与语言 · 计算机科学 2025-09-30 Hakaze Cho , Peng Luo , Mariko Kato , Rin Kaenbyou , Naoya Inoue