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Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which pathological changes begin many years before the onset of clinical symptoms, making early detection essential for timely intervention. T1-weighted (T1w) Magnetic…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Jason Qiu

Generative AI framework-based modeling and prediction of longitudinal human brain images offer an efficient mechanism to track neurodegenerative progression, essential for the assessment of diseases like Alzheimer's. Among the existing…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Ayantika Das , Keerthi Ram , Mohanasankar Sivaprakasam

Accurate quantification of tau pathology via tau positron emission tomography (PET) scan is crucial for diagnosing and monitoring Alzheimer's disease (AD). However, the high cost and limited availability of tau PET restrict its widespread…

计算机视觉与模式识别 · 计算机科学 2025-09-05 Yuxin Gong , Se-in Jang , Wei Shao , Yi Su , Kuang Gong

Early diagnosis of Alzheimer's disease (AD) remains a major challenge due to the subtle and temporally irregular progression of structural brain changes in the prodromal stages. Existing deep learning approaches require large longitudinal…

计算机视觉与模式识别 · 计算机科学 2026-02-10 Maxx Richard Rahman , Mostafa Hammouda , Wolfgang Maass

Accurately modeling longitudinal brain MRI progression is crucial for understanding neurodegenerative diseases and predicting individualized structural changes. Existing state-of-the-art approaches, such as Brain Latent Progression (BrLP),…

计算机视觉与模式识别 · 计算机科学 2026-01-22 Cheng Wan , Bahram Jafrasteh , Ehsan Adeli , Miaomiao Zhang , Qingyu Zhao

Accurate modeling of cognitive decline in Alzheimer's disease is essential for early stratification and personalized management. While tabular predictors provide robust markers of global risk, their ability to capture subtle brain changes…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Nathaniel Putera , Daniel Vilet Rodríguez , Noah Videcrantz , Julia Machnio , Mostafa Mehdipour Ghazi

Early and accurate detection of Alzheimer's disease (AD) is crucial for enabling timely intervention and improving outcomes. However, developing reliable machine learning (ML) models for AD diagnosis is challenging due to limited labeled…

机器学习 · 计算机科学 2025-11-27 Abolfazl Moslemi , Hossein Peyvandi

Diffusion Transformers (DiTs) have emerged as a leading architecture for text-to-image synthesis, producing high-quality and photorealistic images. However, the quadratic scaling properties of the attention in DiTs hinder image generation…

计算机视觉与模式识别 · 计算机科学 2025-08-12 Philipp Becker , Abhinav Mehrotra , Ruchika Chavhan , Malcolm Chadwick , Luca Morreale , Mehdi Noroozi , Alberto Gil Ramos , Sourav Bhattacharya

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

计算机视觉与模式识别 · 计算机科学 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

Generative modeling frameworks have emerged as an effective approach to capture high-dimensional image distributions from large datasets without requiring domain-specific knowledge, a capability essential for longitudinal disease…

计算机视觉与模式识别 · 计算机科学 2025-11-11 Ayantika Das , Arunima Sarkar , Keerthi Ram , Mohanasankar Sivaprakasam

The biological definition of Alzheimer's disease (AD) relies on multi-modal neuroimaging, yet the clinical utility of positron emission tomography (PET) is limited by cost and radiation exposure, hindering early screening at preclinical or…

计算机视觉与模式识别 · 计算机科学 2026-04-17 Tuo Liu , Shuijin Lin , Shaozhen Yan , Haifeng Wang , Jie Lu , Jianhua Ma , Chunfeng Lian

Recent Diffusion Transformers (DiTs) have shown impressive capabilities in generating high-quality single-modality content, including images, videos, and audio. However, it is still under-explored whether the transformer-based diffuser can…

计算机视觉与模式识别 · 计算机科学 2024-06-13 Kai Wang , Shijian Deng , Jing Shi , Dimitrios Hatzinakos , Yapeng Tian

Diffusion Transformer (DiT), an emerging diffusion model for image generation, has demonstrated superior performance but suffers from substantial computational costs. Our investigations reveal that these costs stem from the static inference…

计算机视觉与模式识别 · 计算机科学 2024-10-10 Wangbo Zhao , Yizeng Han , Jiasheng Tang , Kai Wang , Yibing Song , Gao Huang , Fan Wang , Yang You

Alzheimer's disease (AD), characterized by progressive cognitive decline and memory loss, presents a formidable global health challenge, underscoring the critical importance of early and precise diagnosis for timely interventions and…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Arindam Majee , Avisek Gupta , Sourav Raha , Swagatam Das

Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions worldwide, necessitating early and accurate diagnosis for optimal patient management. In recent years, advancements in deep learning have shown remarkable potential…

Diffusion models are the standard toolkit for generative modelling of 3D atomic systems. However, for different types of atomic systems -- such as molecules and materials -- the generative processes are usually highly specific to the target…

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

图像与视频处理 · 电气工程与系统科学 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

Recent progress in diffusion models has significantly advanced the field of human image animation. While existing methods can generate temporally consistent results for short or regular motions, significant challenges remain, particularly…

计算机视觉与模式识别 · 计算机科学 2025-12-29 Shen Zheng , Jiaran Cai , Yuansheng Guan , Shenneng Huang , Xingpei Ma , Junjie Cao , Hanfeng Zhao , Qiang Zhang , Shunsi Zhang , Xiao-Ping Zhang

In recent years, speech diffusion models have advanced rapidly. Alongside the widely used U-Net architecture, transformer-based models such as the Diffusion Transformer (DiT) have also gained attention. However, current DiT speech models…

Diffusion MRI is the modality of choice to study alterations of white matter. In past years, various works have used diffusion MRI for automatic classification of AD. However, classification performance obtained with different approaches is…

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