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Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their…

Fine-tuning helps large language models (LLM) recover degraded information and enhance task performance. Although Low-Rank Adaptation (LoRA) is widely used and effective for fine-tuning, we have observed that its scaling factor can limit or…

Large Language Models (LLMs) have shown significant promise across various natural language processing tasks. However, their application in the field of pathology, particularly for extracting meaningful insights from unstructured medical…

计算与语言 · 计算机科学 2025-03-04 Rachit Saluja , Jacob Rosenthal , Yoav Artzi , David J. Pisapia , Benjamin L. Liechty , Mert R. Sabuncu

Large Language Models (LLMs) have transformed both everyday life and scientific research. However, adapting LLMs from general-purpose models to specialized tasks remains challenging, particularly in resource-constrained environments.…

机器学习 · 计算机科学 2025-09-12 Hao Zhang , Bo Huang , Zhenjia Li , Xi Xiao , Hui Yi Leong , Zumeng Zhang , Xinwei Long , Tianyang Wang , Hao Xu

As large language models (LLMs) continue to scale in size, the computational overhead has become a major bottleneck for task-specific fine-tuning. While low-rank adaptation (LoRA) effectively curtails this cost by confining the weight…

机器学习 · 计算机科学 2026-05-15 Yilang Zhang , Xiaodong Yang , Yiwei Cai , Georgios B. Giannakis

This study examines whether Low-Rank Adaptation (LoRA) fine-tuned Large Language Models (LLMs) can approximate the performance of fully fine-tuned models in generating human-interpretable decisions and explanations for malware…

密码学与安全 · 计算机科学 2025-11-26 Stephen C. Gravereaux , Sheikh Rabiul Islam

Large Language Models (LLMs) have shown strong performance in text-based healthcare tasks. However, their utility in image-based applications remains unexplored. We investigate the effectiveness of LLMs for medical imaging tasks,…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Felicia Liu , Jay J. Yoo , Farzad Khalvati

Low-Rank Adaptation (LoRA) has emerged as one of the most widely used parameter-efficient fine-tuning (PEFT) methods for adapting large language models (LLMs) to downstream tasks. While highly effective in single-task settings, it struggles…

计算与语言 · 计算机科学 2025-10-14 Bo Cheng , Xu Wang , Jinda Liu , Yi Chang , Yuan Wu

Fine-tuning large language models (LLMs) with high parameter efficiency for downstream tasks has become a new paradigm. Low-Rank Adaptation (LoRA) significantly reduces the number of trainable parameters for fine-tuning. Although it has…

计算与语言 · 计算机科学 2024-08-14 Jia-Chen Zhang , Yu-Jie Xiong , He-Xi Qiu , Dong-Hai Zhu , Chun-Ming Xia

Fine-tuning large language models (LLMs) aims to adapt pre-trained models to specific tasks using relatively small and domain-specific datasets. Among Parameter-Efficient Fine-Tuning (PEFT) methods, Low-Rank Adaptation (LoRA) stands out by…

计算与语言 · 计算机科学 2026-04-16 Yarui Cao , Kai Liu

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

计算与语言 · 计算机科学 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Fine-tuning large language models (LLMs) is computationally expensive, and Low-Rank Adaptation (LoRA) provides a cost-effective solution by approximating weight updates through low-rank matrices. In real-world scenarios, LLMs are fine-tuned…

机器学习 · 计算机科学 2025-06-03 Jinda Liu , Yi Chang , Yuan Wu

Low Rank Adaptation (LoRA) has emerged as one of the most widely adopted methods for Parameter Efficient Fine-Tuning (PEFT) of Large Language Models (LLMs). LoRA reduces the number of trainable parameters and memory usage while achieving…

With the productive evolution of large language models (LLMs) in the field of natural language processing (NLP), tons of effort has been made to effectively fine-tune common pre-trained LLMs to fulfill a variety of tasks in one or multiple…

计算与语言 · 计算机科学 2024-02-06 Chao Song , Zhihao Ye , Qiqiang Lin , Qiuying Peng , Jun Wang

Advances in Large Language Models (LLMs) have led to significant interest in their potential to support human experts across a range of domains, including public health. In this work we present automated evaluations of LLMs for public…

Tumor documentation in Germany is largely done manually, requiring reading patient records and entering data into structured databases. Large language models (LLMs) could potentially enhance this process by improving efficiency and…

计算与语言 · 计算机科学 2025-08-08 Stefan Lenz , Arsenij Ustjanzew , Marco Jeray , Meike Ressing , Torsten Panholzer

Medical Large Language Models (LLMs) have demonstrated impressive performance on a wide variety of medical NLP tasks; however, there still lacks a LLM specifically designed for phenotyping identification and diagnosis in cancer domain.…

计算与语言 · 计算机科学 2025-04-02 Mingchen Li , Jiatan Huang , Jeremy Yeung , Anne Blaes , Steven Johnson , Hongfang Liu , Hua Xu , Rui Zhang

Fine-tuning Large Language Models (LLMs) has become a crucial technique for adapting pre-trained models to downstream tasks. However, the enormous size of LLMs poses significant challenges in terms of computational complexity and resource…

计算与语言 · 计算机科学 2024-10-28 Yifei Zhang , Hao Zhu , Aiwei Liu , Han Yu , Piotr Koniusz , Irwin King

Predicting enzymatic reactions is crucial for applications in biocatalysis, metabolic engineering, and drug discovery, yet it remains a complex and resource-intensive task. Large Language Models (LLMs) have recently demonstrated remarkable…

人工智能 · 计算机科学 2025-05-12 Lorenzo Di Fruscia , Jana Marie Weber
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