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Positron Emission Tomography (PET) scan images are one of the bio medical imaging techniques similar to that of MRI scan images but PET scan images are helpful in finding the development of tumors.The PET scan images requires expertise in…

神经与进化计算 · 计算机科学 2013-02-27 A. Meena , K. Raja

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

计算与语言 · 计算机科学 2023-08-24 Loukas Ilias , Dimitris Askounis

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

图像与视频处理 · 电气工程与系统科学 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and to delay further progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical…

计算与语言 · 计算机科学 2023-04-03 Yi Wang , Jiajun Deng , Tianzi Wang , Bo Zheng , Shoukang Hu , Xunying Liu , Helen Meng

The automatic early diagnosis of prodromal stages of Alzheimer's disease is of great relevance for patient treatment to improve quality of life. We address this problem as a multi-modal classification task. Multi-modal data provides richer…

Alzheimer's disease is the most common form of dementia in the western world, however there is no cure available for this devastating neurodegenerative disorder. Despite clinical and experimental evidence implicating the intestinal…

分子网络 · 定量生物学 2015-09-17 T. Harach , N. Marungruang , N. Dutilleul , V. Cheatham , K. D. Mc Coy , J. J. Neher , M. Jucker , F. Fåk , T. , Lasser , T. Bolmont

Information from neuroimaging examinations is increasingly used to support diagnoses of dementia, e.g., Alzheimer's disease. While current clinical practice is mainly based on visual inspection and feature engineering, Deep Learning…

计算机视觉与模式识别 · 计算机科学 2024-07-23 Lisa Anita De Santi , Jörg Schlötterer , Michael Scheschenja , Joel Wessendorf , Meike Nauta , Vincenzo Positano , Christin Seifert

Visualizing and interpreting convolutional neural networks (CNNs) is an important task to increase trust in automatic medical decision making systems. In this study, we train a 3D CNN to detect Alzheimer's disease based on structural MRI…

计算机视觉与模式识别 · 计算机科学 2018-12-07 Johannes Rieke , Fabian Eitel , Martin Weygandt , John-Dylan Haynes , Kerstin Ritter

Positron emission tomography (PET) imaging is an imaging modality for diagnosing a number of neurological diseases. In contrast to Magnetic Resonance Imaging (MRI), PET is costly and involves injecting a radioactive substance into the…

图像与视频处理 · 电气工程与系统科学 2019-08-23 Haoliang Sun , Ronak Mehta , Hao H. Zhou , Zhichun Huang , Sterling C. Johnson , Vivek Prabhakaran , Vikas Singh

Automatic segmentation of the prostate cancer from the multi-modal magnetic resonance images is of critical importance for the initial staging and prognosis of patients. However, how to use the multi-modal image features more efficiently is…

图像与视频处理 · 电气工程与系统科学 2020-11-10 Guokai Zhang , Xiaoang Shen , Ye Luo , Jihao Luo , Zeju Wang , Weigang Wang , Binghui Zhao , Jianwei Lu

Positron emission tomography (PET) with 18F-Fluorodeoxyglucose (FDG) is an established tool in the diagnostic workup of patients with suspected dementing disorders. However, compared to the routinely available magnetic resonance imaging…

计算机视觉与模式识别 · 计算机科学 2025-10-20 Yitong Li , Ralph Buchert , Benita Schmitz-Koep , Timo Grimmer , Björn Ommer , Dennis M. Hedderich , Igor Yakushev , Christian Wachinger

Electroencephalography (EEG) is a fundamental modality for cognitive state monitoring in brain-computer interfaces (BCIs). However, it is highly susceptible to intrinsic signal errors and human-induced labeling errors, which lead to label…

机器学习 · 计算机科学 2025-12-15 Hyo-Jeong Jang , Hye-Bin Shin , Seong-Whan Lee

Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…

音频与语音处理 · 电气工程与系统科学 2025-09-29 Jiawen Kang , Dongrui Han , Lingwei Meng , Jingyan Zhou , Jinchao Li , Xixin Wu , Helen Meng

Understanding cellular responses to stimuli is crucial for biological discovery and drug development. Transcriptomics provides interpretable, gene-level insights, while microscopy imaging offers rich predictive features but is harder to…

Integrating functional magnetic resonance imaging (fMRI) connectivity data with phenotypic textual descriptors (e.g., disease label, demographic data) holds significant potential to advance our understanding of neurological conditions.…

机器学习 · 计算机科学 2025-03-31 Yanting Yang , Xiaoxiao Li

Accumulation of amyloid beta proteins is a defining feature of Alzheimer's disease, and is usually accompanied by cerebrovascular pathology. Evidence suggests that amyloid beta and cerebrovascular pathology are mutually reinforcing; in…

数值分析 · 数学 2026-01-14 Mattia Corti , Andrew Ahern , Alain Goriely , Ellen Kuhl , Paola F. Antonietti

We propose a novel framework for Alzheimer's disease (AD) detection using brain MRIs. The framework starts with a data augmentation method called Brain-Aware Replacements (BAR), which leverages a standard brain parcellation to replace…

计算机视觉与模式识别 · 计算机科学 2022-07-22 Mehmet Saygın Seyfioğlu , Zixuan Liu , Pranav Kamath , Sadjyot Gangolli , Sheng Wang , Thomas Grabowski , Linda Shapiro

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

计算机视觉与模式识别 · 计算机科学 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham

Multi-modal magnetic resonance imaging (MRI) is a crucial method for analyzing the human brain. It is usually used for diagnosing diseases and for making valuable decisions regarding the treatments - for instance, checking for gliomas in…

图像与视频处理 · 电气工程与系统科学 2021-05-26 Ashwin Nalwade , Jackie Kisa

We propose a novel framework for integrating fragmented multi-modal data in Alzheimer's disease (AD) research using large language models (LLMs) and knowledge graphs. While traditional multimodal analysis requires matched patient IDs across…

机器学习 · 计算机科学 2025-08-19 Kanan Kiguchi , Yunhao Tu , Katsuhiro Ajito , Fady Alnajjar , Kazuyuki Murase