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相关论文: Gaussian Graphical Models for Functional Connectiv…

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Alzheimer's disease (AD) is characterized by a sequence of pathological changes, which are commonly assessed in vivo using MRI and PET. Currently, the most approaches to analyze statistical associations between brain regions rely on Pearson…

神经元与认知 · 定量生物学 2020-03-30 Martin Dyrba , Reza Mohammadi , Michel J. Grothe , Thomas Kirste , Stefan J. Teipel

Functional brain networks are well described and estimated from data with Gaussian Graphical Models (GGMs), e.g. using sparse inverse covariance estimators. Comparing functional connectivity of subjects in two populations calls for…

机器学习 · 统计学 2016-11-21 Eugene Belilovsky , Gaël Varoquaux , Matthew B. Blaschko

Gaussian Graphical Models (GGM) are popularly used in neuroimaging studies based on fMRI, EEG or MEG to estimate functional connectivity, or relationships between remote brain regions. In multi-subject studies, scientists seek to identify…

统计方法学 · 统计学 2017-05-01 Manjari Narayan , Genevera I. Allen , Steffie Tomson

The early detection of Alzheimer's disease (AD) requires an understanding of the relationships between a wide range of features. Conditional independencies and partial correlations are suitable measures for these relationships, because they…

应用统计 · 统计学 2025-01-22 Lucas Vogels , Reza Mohammadi , Marit Schoonhoven , S. Ilker Birbil , Martin Dyrba

Functional Gaussian graphical models (GGM) used for analyzing multivariate functional data customarily estimate an unknown graphical model representing the conditional relationships between the functional variables. However, in many…

统计方法学 · 统计学 2024-10-03 Debangan Dey , Sudipto Banerjee , Martin Lindquist , Abhirup Datta

We discuss the Gaussian graphical model (GGM; an undirected network of partial correlation coefficients) and detail its utility as an exploratory data analysis tool. The GGM shows which variables predict one-another, allows for sparse…

统计方法学 · 统计学 2018-02-09 Sacha Epskamp , Lourens J. Waldorp , René Mõttus , Denny Borsboom

The Gaussian graphical model (GGM) incorporates an undirected graph to represent the conditional dependence between variables, with the precision matrix encoding partial correlation between pair of variables given the others. To achieve…

统计方法学 · 统计学 2023-07-03 Yueqi Qian , Xianghong Hu , Can Yang

Functional MRI is a neuroimaging technique that analyzes the functional activity of the brain by measuring blood-oxygen-level-dependent signals throughout the brain. The derived functional features can be used for investigating brain…

神经元与认知 · 定量生物学 2026-02-16 Giorgio Dolci , Silvia Saglia , Lorenza Brusini , Vince D. Calhoun , Ilaria Boscolo Galazzo , Gloria Menegaz

In recent literature, the Gaussian Graphical model (GGM; Lauritzen, 1996),a network of partial correlation coefficients, has been used to capture potential dynamic relationships between observed variables. The GGM can be estimated using…

统计方法学 · 统计学 2017-09-25 Sacha Epskamp

Graphical models are commonly used to represent conditional dependence relationships between variables. There are multiple methods available for exploring them from high-dimensional data, but almost all of them rely on the assumption that…

机器学习 · 统计学 2020-04-22 Tianxi Li , Cheng Qian , Elizaveta Levina , Ji Zhu

Case vs control comparisons have been the classical approach to the study of neurological diseases. However, most patients will not fall cleanly into either group. Instead, clinicians will typically find patients that cannot be classified…

机器学习 · 统计学 2012-07-20 Iead Rezek , Christian Beckmann

Knowledge of functional groupings of neurons can shed light on structures of neural circuits and is valuable in many types of neuroimaging studies. However, accurately determining which neurons carry out similar neurological tasks via…

机器学习 · 统计学 2019-06-03 Tianyi Yao , Genevera I. Allen

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

神经元与认知 · 定量生物学 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

医学物理 · 物理学 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

图像与视频处理 · 电气工程与系统科学 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

Determining functional brain connectivity is crucial to understanding the brain and neural differences underlying disorders such as autism. Recent studies have used Gaussian graphical models to learn brain connectivity via statistical…

神经元与认知 · 定量生物学 2017-09-22 Chandan Singh , Beilun Wang , Yanjun Qi

Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…

神经元与认知 · 定量生物学 2025-09-24 Ali Khazaee , Abdolreza Mohammadi , Ruairi O'Reilly

Alzheimer's disease is the most common neurodegenerative disease. The aim of this study is to infer structural changes in brain connectivity resulting from disease progression using cortical thickness measurements from a cohort of…

Graphical model has been widely used to investigate the complex dependence structure of high-dimensional data, and it is common to assume that observed data follow a homogeneous graphical model. However, observations usually come from…

统计方法学 · 统计学 2016-01-01 Kevin Lee , Lingzhou Xue

Multiple modalities of biomarkers have been proved to be very sensitive in assessing the progression of Alzheimer's disease (AD), and using these modalities and machine learning algorithms, several approaches have been proposed to assist in…

机器学习 · 统计学 2017-12-05 Chen Fang , Panuwat Janwattanapong , Chunfei Li , Malek Adjouadi
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