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Personalized alignment is crucial for enabling Large Language Models (LLMs) to engage effectively in user-centric interactions. However, current methods face a dual challenge: they fail to infer users' deep implicit preferences (including…

人工智能 · 计算机科学 2026-04-29 Peiming Li , Zhiyuan Hu , Yang Tang , Shiyu Li , Xi Chen

Multimodal large language models (MLLMs) hold considerable promise for applications in healthcare. However, their deployment in safety-critical settings is hindered by two key limitations: (i) sensitivity to prompt design, and (ii) a…

计算机视觉与模式识别 · 计算机科学 2025-10-14 Anita Kriz , Elizabeth Laura Janes , Xing Shen , Tal Arbel

Reward Modeling is critical in evaluating and improving the generation of Large Language Models (LLMs). While numerous recent works have shown its feasibility in improving safety, helpfulness, reasoning, and instruction-following ability,…

计算与语言 · 计算机科学 2025-11-13 Hanning Zhang , Juntong Song , Juno Zhu , Yuanhao Wu , Tong Zhang , Cheng Niu

Preference learning is critical for aligning large language models (LLMs) with human values, with the quality of preference datasets playing a crucial role in this process. While existing metrics primarily assess data quality based on…

机器学习 · 计算机科学 2025-03-05 Kexin Huang , Junkang Wu , Ziqian Chen , Xue Wang , Jinyang Gao , Bolin Ding , Jiancan Wu , Xiangnan He , Xiang Wang

Large Language Models (LLMs) have emerged as promising solutions for a variety of medical and clinical decision support applications. However, LLMs are often subject to different types of biases, which can lead to unfair treatment of…

计算与语言 · 计算机科学 2024-08-23 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

计算与语言 · 计算机科学 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

计算与语言 · 计算机科学 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

With the rapid advancement of generative artificial intelligence, large language models (LLMs) are increasingly adopted in industrial domains, offering new opportunities for Prognostics and Health Management (PHM). These models help address…

Aligning Large Language Models (LLMs) with human preferences is critical, yet traditional fine-tuning methods are computationally expensive and inflexible. While test-time alignment offers a promising alternative, existing approaches often…

人工智能 · 计算机科学 2026-01-16 Tiesunlong Shen , Rui Mao , Jin Wang , Heming Sun , Jian Zhang , Xuejie Zhang , Erik Cambria

Reinforcement learning with human feedback for aligning large language models (LLMs) trains a reward model typically using ranking loss with comparison pairs.However, the training procedure suffers from an inherent problem: the uncontrolled…

计算与语言 · 计算机科学 2024-09-19 Hang Zhou , Chenglong Wang , Yimin Hu , Tong Xiao , Chunliang Zhang , Jingbo Zhu

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Multimodal large language models (MLLMs) hold significant potential in medical applications, including disease diagnosis and clinical decision-making. However, these tasks require highly accurate, context-sensitive, and professionally…

计算与语言 · 计算机科学 2025-09-01 Meidan Ding , Jipeng Zhang , Wenxuan Wang , Cheng-Yi Li , Wei-Chieh Fang , Hsin-Yu Wu , Haiqin Zhong , Wenting Chen , Linlin Shen

Medical treatments often involve a sequence of decisions, each informed by previous outcomes. This process closely aligns with reinforcement learning (RL), a framework for optimizing sequential decisions to maximize cumulative rewards under…

机器学习 · 计算机科学 2024-10-15 Ali Shirali , Alexander Schubert , Ahmed Alaa

Preference alignment in Large Language Models (LLMs) has significantly improved their ability to adhere to human instructions and intentions. However, existing direct alignment algorithms primarily focus on relative preferences and often…

机器学习 · 计算机科学 2025-05-13 Shenao Zhang , Zhihan Liu , Boyi Liu , Yufeng Zhang , Yingxiang Yang , Yongfei Liu , Liyu Chen , Tao Sun , Zhaoran Wang

Despite notable advancements in Multimodal Large Language Models (MLLMs), most state-of-the-art models have not undergone thorough alignment with human preferences. This gap exists because current alignment research has primarily achieved…

Multimodal Large Language Models (MLLMs) pose critical safety challenges, as they are susceptible not only to adversarial attacks such as jailbreaking but also to inadvertently generating harmful content for benign users. While internal…

机器学习 · 计算机科学 2026-03-17 Ming Wen , Kun Yang , Xin Chen , Jingyu Zhang , Dingding Han , Shiwen Cui , Yuedong Xu

Large Language Models (LLMs) are prone to hallucination, especially during multi-hop and reasoning-intensive tasks such as mathematical problem solving. While Outcome Reward Models verify only final answers, Process Reward Models (PRMs)…

计算与语言 · 计算机科学 2025-05-27 Tej Deep Pala , Panshul Sharma , Amir Zadeh , Chuan Li , Soujanya Poria

Large language models (LLMs) are increasingly being used as decision aids. However, users have diverse values and preferences that can affect their decision-making, which requires novel methods for LLM alignment and personalization.…

Personalized alignment from preference data has focused primarily on improving personal reward model (RM) accuracy, with the implicit assumption that better preference ranking translates to better personalized behavior. However, in…

人工智能 · 计算机科学 2026-01-09 Fady Rezk , Yuangang Pan , Chuan-Sheng Foo , Xun Xu , Nancy Chen , Henry Gouk , Timothy Hospedales

Applying large language models (LLMs) to assist in psycho-counseling is an emerging and meaningful approach, driven by the significant gap between patient needs and the availability of mental health support. However, current LLMs struggle…

计算与语言 · 计算机科学 2026-04-14 Mian Zhang , Shaun M. Eack , Zhiyu Zoey Chen