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We prove the existence of a solution to an equation governing the number density within a compact domain of a discrete particle system for a prescribed class of particle interactions taking into account the effects of the diffusion and…

概率论 · 数学 2007-05-23 Clive G. Wells

We show that a scaling approach successfully characterizes clustering and intermittency in space and time, in systems of noninteracting particles driven by fluctuating surfaces. We study both the steady state and the approach to it, for…

软凝聚态物质 · 物理学 2019-01-15 Tapas Singha , Mustansir Barma

Traveling fronts describe the transition between two alternative states in a great number of physical and biological systems. Examples include the spread of beneficial mutations, chemical reactions, and the invasions by foreign species. In…

统计力学 · 物理学 2020-07-14 Ching-Hao Wang , Sakib Matin , Ashish B. George , Kirill S. Korolev

Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

生物物理 · 物理学 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano

Many imaging techniques for biological systems -- like fixation of cells coupled with fluorescence microscopy -- provide sharp spatial resolution in reporting locations of individuals at a single moment in time but also destroy the dynamics…

亚细胞过程 · 定量生物学 2024-05-15 Christopher E. Miles , Scott A. McKinley , Fangyuan Ding , Richard B. Lehoucq

We consider a partial differential equation model for the growth of heterogeneous cell populations subdivided into multiple distinct discrete phenotypes. In this model, cells preferentially move towards regions where they feel less…

偏微分方程分析 · 数学 2025-04-04 José A. Carrillo , Tommaso Lorenzi , Fiona R. Macfarlane

From the formation of animal flocks to the emergence of coordinate motion in bacterial swarms, at all scales populations of motile organisms display coherent collective motion. This consistent behavior strongly contrasts with the difference…

软凝聚态物质 · 物理学 2013-11-11 Antoine Bricard , Jean-Baptiste Caussin , Nicolas Desreumaux , Olivier Dauchot , Denis Bartolo

Bacteria evolve in volatile environments and complex spatial structures. Migration, fluctuations and environmental variability therefore have a significant impact on the evolution of microbial populations. Here, we consider a class of…

种群与进化 · 定量生物学 2025-11-24 Matthew Asker , Mohamed Swailem , Uwe C. Täuber , Mauro Mobilia

Discrete time, spatially extended models play an important role in ecology, modelling population dynamics of species ranging from micro-organisms to birds. An important question is how 'bottom up', individual-based models can be…

种群与进化 · 定量生物学 2023-01-20 Linnéa Gyllingberg , David J. T. Sumpter , Åke Brännström

Single and collective cell migration are fundamental processes critical for physiological phenomena ranging from embryonic development and immune response to wound healing and cancer metastasis. To understand cell migration from a physical…

生物物理 · 物理学 2023-10-10 David B. Brückner , Chase P. Broedersz

Motility initiation in crawling cells requires transformation of a symmetric state into a polarized state. In contrast, motility arrest is associated with re-symmetrization of the internal configuration of a cell. Experiments on keratocytes…

生物物理 · 物理学 2015-10-28 Pierre Recho , Thibaut Putelat , Lev Truskinovsky

Substrate-based cell motility is essential for fundamental biological processes, such as tissue growth, wound healing and immune response. Even if a comprehensive understanding of this motility mode remains elusive, progress has been…

细胞行为 · 定量生物学 2016-05-23 Wieland Marth , Axel Voigt

Active matter physics and swarm robotics have provided powerful tools for the study and control of ensembles driven by internal sources. At the macroscale, controlling swarms typically utilizes significant memory, processing power, and…

Understanding the out-of-equilibrium properties of noisy microscale systems and the extent to which they can be modulated externally, is a crucial scientific and technological challenge. It holds the promise to unlock disruptive new…

软凝聚态物质 · 物理学 2022-09-21 Stephen Williams , Raphaël Jeanneret , Idan Tuval , Marco Polin

Cell migration in confining physiological environments relies on the concerted dynamics of several cellular components, including protrusions, adhesions with the environment, and the cell nucleus. However, it remains poorly understood how…

Population structure induced by both spatial embedding and more general networks of interaction, such as model social networks, have been shown to have a fundamental effect on the dynamics and outcome of evolutionary games. These effects…

种群与进化 · 定量生物学 2009-11-13 Gergely J Szollosi , Imre Derenyi

Collective cell migration underlies important biological processes, such as embryonic development, wound healing and cancer invasion. While many aspects of single cell movements are now well established, the mechanisms leading to…

A microscopic, stochastic, minimal model for collective and cohesive motion of identical self-propelled particles is introduced. Even though the particles interact strictly locally in a very noisy manner, we show that cohesion can be…

统计力学 · 物理学 2010-01-05 Guillaume Gregoire , Hugues Chate , Yuhai Tu

Competition between independently arising beneficial mutations is enhanced in spatial populations due to the linear rather than exponential growth of clones. Recent theoretical studies have pointed out that the resulting fitness dynamics is…

种群与进化 · 定量生物学 2014-11-11 Jakub Otwinowski , Joachim Krug

There are rich emergent phase behaviors in non-equilibrium active systems. Flocking and clustering are two representative dynamic phases. The relationship between these two phases is still unclear. In the paper, we numerically investigate…

软凝聚态物质 · 物理学 2023-08-09 Lu Chen , Bokai Zhang , Z. C. Tu