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Parkinsons Disease (PD) is a neurodegenerative disorder resulting in motor deficits due to advancing degeneration of dopaminergic neurons. PD patients report experiencing tremor, rigidity, visual impairment, bradykinesia, and several…

计算机视觉与模式识别 · 计算机科学 2023-04-05 Krish Desai

Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…

信号处理 · 电气工程与系统科学 2023-08-16 Niloufar Delfan , Mohammadreza Shahsavari , Sadiq Hussain , Robertas Damaševičius , U. Rajendra Acharya

Parkinson's disease (PD) is a debilitating neurodegenerative disease that has severe impacts on an individual's quality of life. Compared with structural and functional MRI-based biomarkers for the disease, electroencephalography (EEG) can…

机器学习 · 计算机科学 2024-08-05 Christopher Neves , Yong Zeng , Yiming Xiao

Detecting Parkinson's Disease in its early stages using EEG data presents a significant challenge. This paper introduces a novel approach, representing EEG data as a 15-variate series of bandpower and peak frequency values/coefficients. The…

Resting-state EEG (rs-EEG) has been demonstrated to aid in Parkinson's disease (PD) diagnosis. In particular, the power spectral density (PSD) of low-frequency bands ({\delta} and {\theta}) and high-frequency bands ({\alpha} and \b{eta})…

In this study we focus on the diagnosis of Parkinson's Disease (PD) based on electroencephalogram (EEG) signals. We propose a new approach inspired by the functioning of the brain that uses the dynamics, frequency and temporal content of…

系统与控制 · 电气工程与系统科学 2023-03-31 Houssem Meghnoudj , Bogdan Robu , Mazen Alamir

Parkinsons disease (PD) diagnosis is challenging due to subtle early clinical signs. F-DOPA PET is commonly used for early PD diagnosis. We explore the potential of machine-learning (ML) based EEG features extracted from single-channel EEG…

神经元与认知 · 定量生物学 2023-08-08 Lior Molcho , Neta B. Maimon , Neomi Hezi , Talya Zeimer , Nathan Intrator , Tanya Gurevich

Neural biomarkers that can classify or predict disease are of broad interest to the neurological and psychiatric communities. Such biomarkers can be informative of disease state or treatment efficacy, even before there are changes in…

神经元与认知 · 定量生物学 2024-10-10 Xiaoxiao Sun , Chongkun Zhao , Sharath Koorathota , Paul Sajda

While Parkinson's disease (PD) is typically characterized by motor disorder, there is evidence of diminished emotion perception in PD patients. This study examines the utility of affective Electroencephalography (EEG) signals to understand…

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction and abnormal neural oscillations. These symptoms can be modulated through electrical stimulation. Traditional neural activity analysis in PD has…

神经元与认知 · 定量生物学 2025-02-19 Jibum Kim , Hanseul Choi , Gaeun Kim , Sunggu Yang , Eunha Baeg , Donggue Kim , Seongwon Jin , Sangwon Byun

Parkinson's Disease PD is a progressive neurodegenerative disorder that affects motor and cognitive functions with early diagnosis being critical for effective clinical intervention Electroencephalography EEG offers a noninvasive and…

Recordings of electrical brain activity carry information about a person's cognitive health. For recording EEG signals, a very common setting is for a subject to be at rest with its eyes closed. Analysis of these recordings often involve a…

神经元与认知 · 定量生物学 2018-12-18 Sebastian Mathias Keller , Maxim Samarin , Antonia Meyer , Vitalii Kosak , Ute Gschwandtner , Peter Fuhr , Volker Roth

Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neurons in the substantia nigra pars compacta, which causes both…

神经元与认知 · 定量生物学 2024-11-01 Hina Shaheen , Roderick Melnik

Up to 90% of patients with Parkinson's disease (PD) suffer from hypokinetic dysathria (HD) which is also manifested in the field of phonation. Clinical signs of HD like monoloudness, monopitch or hoarse voice are usually quantified by…

While EEG features differentiate Major Depressive Disorder (MDD) from healthy controls (HC), their clinical utility as biomarkers depends on a monotonic trajectory across the disease spectrum, from the acute (AC) phase to the maintenance…

神经元与认知 · 定量生物学 2026-03-05 Feng Yan , Xuteng Wang , Shuyu Yang , Yue Zhao , Xiaobin Wong , Zhiren Wang

Patterns of brain activity are associated with different brain processes and can be used to identify different brain states and make behavioral predictions. However, the relevant features are not readily apparent and accessible. To mine…

Electroencephalography (EEG) is establishing itself as an important, low-cost, noninvasive diagnostic tool for the early detection of Parkinson's Disease (PD). In this context, EEG-based Deep Learning (DL) models have shown promising…

This study investigates EEG as a potential early biomarker by applying deep learning techniques to resting-state EEG recordings from 31 subjects (15 with PD and 16 healthy controls). EEG signals underwent preprocessing to remove tremor…

神经元与认知 · 定量生物学 2025-03-25 Artem Lensky

Parkinson's disease (PD) poses a growing challenge due to its increasing prevalence, complex pathology, and functional ramifications. Electroencephalography (EEG), when integrated with artificial intelligence (AI), holds promise for…

信号处理 · 电气工程与系统科学 2025-03-31 Anna Kurbatskaya , Fredrik Nilsen Låder , Andreas Solvang Nese , Kolbjørn Brønnick , Alvaro Fernandez-Quilez

Mobility is severely impacted in patients with Parkinson's disease (PD), especially when they experience involuntary stopping from the freezing of gait (FOG). Understanding the neurophysiological difference between "voluntary stopping" and…

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