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The structure of human sleep changes across development as it consolidates from the polyphasic sleep of infants to the single nighttime sleep period typical in adults. Across this same developmental period, time scales of the homeostatic…

神经元与认知 · 定量生物学 2017-10-17 K. Kalmbach , V. Booth , C. G. Diniz Behn

Sleep is one of the most noticeable and widespread phenomena occurring in multicellular animals. Nevertheless, no consensus for a theory of its origins has emerged. In particular, no explicit, quantitative theory exists that elucidates or…

其他定量生物学 · 定量生物学 2007-05-23 Van M. Savage , Geoffrey B. West

In human sleep staging models, augmenting the temporal context of the input to the range of tens of minutes has recently demonstrated performance improvement. In contrast, the temporal context of mouse sleep staging models is typically in…

神经元与认知 · 定量生物学 2024-06-26 Javier García Ciudad , Morten Mørup , Birgitte Rahbek Kornum , Alexander Neergaard Zahid

Sleep is characterized by non-rapid eye movement (nREM) sleep, originating from widespread neuronal synchrony, and REM sleep, with neuronal desynchronization akin to waking behavior. While these were thought to be global brain states,…

神经元与认知 · 定量生物学 2024-05-29 Davor Curic , Surjeet Singh , Mojtaba Nazari , Majid H. Mohajerani , Joern Davidsen

Sleep traits are shaped by genetic and environmental factors and may influence many health conditions. The All of Us Research Program, which includes EHR, physical measurements, genomic data, and wearable data across ancestry groups,…

基因组学 · 定量生物学 2026-05-25 Jiheum Park , Stephanie Y. Shue , Rocio Barragan , Jeong Yun Yang , Tian Gu , Chin Hur , Marie-Pierre St-Onge

Sleep is essential for the maintenance of the brain and the body, yet many features of sleep are poorly understood and mathematical models are an important tool for probing proposed biological mechanisms. The most well-known mathematical…

神经元与认知 · 定量生物学 2015-06-17 Anne C. Skeldon , Derk-Jan Dijk , Gianne Derks

Sleep behavior significantly impacts health and acts as an indicator of physical and mental well-being. Monitoring and predicting sleep behavior with ubiquitous sensors may therefore assist in both sleep management and tracking of related…

机器学习 · 计算机科学 2024-01-30 Maryam Khalid , Elizabeth B. Klerman , Andrew W. Mchill , Andrew J. K. Phillips , Akane Sano

Transitions in the dynamics of complex systems can be characterized by changes in the synchronization behavior of their components. Taking the human cardio-respiratory system as an example and using an automated procedure for screening the…

数据分析、统计与概率 · 物理学 2009-11-13 Ronny Bartsch , Jan W. Kantelhardt , Thomas Penzel , Shlomo Havlin

Slow-wave sleep in mammalians is characterized by a change of large-scale cortical activity currently paraphrased as cortical Up/Down states. A recent experiment demonstrated a bistable collective behaviour in ferret slices, with the…

神经元与认知 · 定量生物学 2012-06-12 Hong-Viet V. Ngo , Jan Köhler , Jörg Mayer , Jens Christian Claussen , Heinz Georg Schuster

Human sleep is cyclical with a period of approximately 90 minutes, implying long temporal dependency in the sleep data. Yet, exploring this long-term dependency when developing sleep staging models has remained untouched. In this work, we…

Human cognitive performance is critical to productivity, learning, and accident avoidance. Cognitive performance varies throughout each day and is in part driven by intrinsic, near 24-hour circadian rhythms. Prior research on the impact of…

人机交互 · 计算机科学 2017-02-28 Tim Althoff , Eric Horvitz , Ryen W. White , Jamie Zeitzer

We study correlation properties of the magnitude and the sign of the increments in the time intervals between successive heartbeats during light sleep, deep sleep, and REM sleep using the detrended fluctuation analysis method. We find…

Increasing evidence suggests that cortical dynamics during wake exhibits long-range temporal correlations suitable to integrate inputs over extended periods of time to increase the signal-to-noise ratio in decision-making and working memory…

神经元与认知 · 定量生物学 2017-06-14 Christian Meisel , Andreas Klaus , Vladyslav V. Vyazovskiy , Dietmar Plenz

Learning new tasks and skills in succession without losing prior learning (i.e., catastrophic forgetting) is a computational challenge for both artificial and biological neural networks, yet artificial systems struggle to achieve parity…

神经与进化计算 · 计算机科学 2022-09-13 Brian S. Robinson , Clare W. Lau , Alexander New , Shane M. Nichols , Erik C. Johnson , Michael Wolmetz , William G. Coon

Sleep is essential for learning and cognition, but the mechanisms by which it stabilizes learning, supports creativity, and manages the energy consumption of networks engaged in post-sleep task have not been yet modelled. During sleep, the…

Sleep is considered to play an essential role in memory reorganization. Despite its importance, classical theoretical models did not focus on some sleep characteristics. Here, we review recent theoretical approaches investigating their…

神经元与认知 · 定量生物学 2023-10-23 Kensuke Yoshida , Taro Toyoizumi

Three abilities - the ability to recognize sounds, the ability to visually recognize movement and the ability to keep an upright standing position - can function only with using precise measurements of the short time intervals. Other…

综合物理 · 物理学 2020-07-28 Michael Rvachov

Circadian rhythms influence multiple essential biological activities including sleep, performance, and mood. The dim light melatonin onset (DLMO) is the gold standard for measuring human circadian phase (i.e., timing). The collection of…

机器学习 · 计算机科学 2022-03-03 Cheng Wan , Andrew W. McHill , Elizabeth Klerman , Akane Sano

Epilepsy is a common, chronic neurological disorder characterized by recurrent seizures caused by sudden bursts of abnormal electrical activity in the brain. Seizures can often be unpredictable, leading to uncertainty and anxiety for people…

Objectives: The study aims to investigate the relationship between insomnia and response time. Additionally, it aims to develop a machine learning model to predict the presence of insomnia in participants using response time data. Methods:…

机器学习 · 计算机科学 2023-10-16 Zhao Su , Rongxun Liu , Keyin Zhou , Xinru Wei , Ning Wang , Zexin Lin , Yuanchen Xie , Jie Wang , Fei Wang , Shenzhong Zhang , Xizhe Zhang
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