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Deep Reinforcement Learning (DRL) has achieved remarkable success in sequential decision-making tasks across diverse domains, yet its reliance on black-box neural architectures hinders interpretability, trust, and deployment in high-stakes…

机器学习 · 计算机科学 2025-02-12 Zelei Cheng , Jiahao Yu , Xinyu Xing

Automatic differential diagnosis (DDx) is an essential medical task that generates a list of potential diseases as differentials based on patient symptom descriptions. In practice, interpreting these differential diagnoses yields…

计算与语言 · 计算机科学 2024-11-08 Shuang Zhou , Mingquan Lin , Sirui Ding , Jiashuo Wang , Genevieve B. Melton , James Zou , Rui Zhang

Reinforcement Learning (RL) has been shown to substantially improve the reasoning capability of small and large language models (LLMs), but existing approaches typically rely on verifiable rewards, hence ground truth labels. We propose an…

计算与语言 · 计算机科学 2026-04-06 Yiyang Shen , Lifu Tu , Weiran Wang

We study multimodal survival analysis integrating clinical text, tabular covariates, and genomic profiles using locally deployable large language models (LLMs). As many institutions face tight computational and privacy constraints, this…

机器学习 · 计算机科学 2026-03-24 Moritz Gögl , Christopher Yau

The application of Artificial Intelligence (AI) in healthcare has been revolutionary, especially with the recent advancements in transformer-based Large Language Models (LLMs). However, the task of understanding unstructured electronic…

计算与语言 · 计算机科学 2023-08-08 Shivani Shekhar , Simran Tiwari , T. C. Rensink , Ramy Eskander , Wael Salloum

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

计算与语言 · 计算机科学 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

计算与语言 · 计算机科学 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Large language models (LLMs) are entering clinician workflows, yet evaluations rarely measure how clinician reasoning shapes model behavior during clinical interactions. We combined 61 New England Journal of Medicine Case Records with 92…

Existing approaches for Large language model (LLM) detoxification generally rely on training on large-scale non-toxic or human-annotated preference data, designing prompts to instruct the LLM to generate safe content, or modifying the model…

计算与语言 · 计算机科学 2025-06-03 Yuanhe Tian , Mingjie Deng , Guoqing Jin , Yan Song

One of the major barriers to using large language models (LLMs) in medicine is the perception they use uninterpretable methods to make clinical decisions that are inherently different from the cognitive processes of clinicians. In this…

计算与语言 · 计算机科学 2023-08-15 Thomas Savage , Ashwin Nayak , Robert Gallo , Ekanath Rangan , Jonathan H Chen

While large language models hold promise for complex medical applications, their development is hindered by the scarcity of high-quality reasoning data. To address this issue, existing approaches typically distill chain-of-thought reasoning…

机器学习 · 计算机科学 2026-04-14 Haolin Li , Shuyang Jiang , Ruipeng Zhang , Jiangchao Yao , Ya Zhang , Yanfeng Wang

We introduce a method for efficient multi-label text classification with large language models (LLMs), built on reformulating classification tasks as sequences of dichotomic (yes/no) decisions. Instead of generating all labels in a single…

计算与语言 · 计算机科学 2025-11-07 Mikołaj Langner , Jan Eliasz , Ewa Rudnicka , Jan Kocoń

Large Language Models (LLMs) have shown strong potential in complex medical reasoning yet face diminishing gains under inference scaling laws. While existing studies augment LLMs with various knowledge types, it remains unclear how…

人工智能 · 计算机科学 2026-02-10 Yu Zhao , Hao Guan , Yongcheng Jing , Ying Zhang , Dacheng Tao

The diagnosis of most mental disorders, including psychiatric evaluations, primarily depends on dialogues between psychiatrists and patients. This subjective process can lead to variability in diagnoses across clinicians and patients,…

Large Language Models (LLMs) are increasingly adopted as evaluators, offering a scalable alternative to human annotation. However, existing supervised fine-tuning (SFT) approaches often fall short in domains that demand complex reasoning.…

计算与语言 · 计算机科学 2025-11-04 Nuo Chen , Zhiyuan Hu , Qingyun Zou , Jiaying Wu , Qian Wang , Bryan Hooi , Bingsheng He

Large Language Models (LLMs) are increasingly deployed to automatically label and analyze educational dialogue at scale, yet current pipelines lack reliable ways to detect when models are wrong. We investigate whether reasoning generated by…

计算与语言 · 计算机科学 2026-02-11 Bakhtawar Ahtisham , Kirk Vanacore , Zhuqian Zhou , Jinsook Lee , Rene F. Kizilcec

Large language models (LLMs) and small language models (SLMs) are being adopted at remarkable speed, although their safety still remains a serious concern. With the advent of multilingual S/LLMs, the question now becomes a matter of scale:…

High-assurance reasoning, particularly in critical domains such as law and medicine, requires conclusions that are accurate, verifiable, and explicitly grounded in evidence. This reasoning relies on premises codified from rules, statutes,…

General Multimodal Large Language Models (MLLMs) often underperform in capturing domain-specific nuances in medical diagnosis, trailing behind fully supervised baselines. Although fine-tuning provides a remedy, the high costs of expert…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Wenkai Zhao , Zipei Wang , Mengjie Fang , Di Dong , Jie Tian , Lingwei Zhang

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

信息检索 · 计算机科学 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng