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Accurate characterization of glioma is crucial for clinical decision making. A delineation of the tumor is also desirable in the initial decision stages but is a time-consuming task. Leveraging the latest GPU capabilities, we developed a…

When developing Computer Aided Detection (CAD) systems for Digital Breast Tomosynthesis (DBT), the complexity arising from the volumetric nature of the modality poses significant technical challenges for obtaining large-scale accurate…

计算机视觉与模式识别 · 计算机科学 2024-09-26 Laurent Dillard , Hyeonsoo Lee , Weonsuk Lee , Tae Soo Kim , Ali Diba , Thijs Kooi

Cancer prognostication is a challenging task in computational pathology that requires context-aware representations of histology features to adequately infer patient survival. Despite the advancements made in weakly-supervised deep…

图像与视频处理 · 电气工程与系统科学 2021-07-29 Richard J. Chen , Ming Y. Lu , Muhammad Shaban , Chengkuan Chen , Tiffany Y. Chen , Drew F. K. Williamson , Faisal Mahmood

Ductal carcinoma in situ (DCIS) is a non-invasive breast cancer that can progress into invasive ductal carcinoma (IDC). Studies suggest DCIS is often overtreated since a considerable part of DCIS lesions may never progress into IDC. Lower…

Circulating Tumor Cells (CTCs) bear great promise as biomarkers in tumor prognosis. However, the process of identification and later enumeration of CTCs require manual labor, which is error-prone and time-consuming. The recent developments…

计算机视觉与模式识别 · 计算机科学 2022-08-08 Elena Alexander , Kam W. Leong , Andrew F. Laine

Accurate and robust drug response prediction is of utmost importance in precision medicine. Although many models have been developed to utilize the representations of drugs and cancer cell lines for predicting cancer drug responses (CDR),…

定量方法 · 定量生物学 2023-11-22 Xiaoqiong Xia , Chaoyu Zhu , Yuqi Shan , Fan Zhong , Lei Liu

This project intends to study a cardiovascular disease risk early warning model based on one-dimensional convolutional neural networks. First, the missing values of 13 physiological and symptom indicators such as patient age, blood glucose,…

机器学习 · 计算机科学 2024-06-14 Yuxiang Hu , Jinxin Hu , Ting Xu , Bo Zhang , Jiajie Yuan , Haozhang Deng

Drug combinations are frequently used for the treatment of cancer patients in order to increase efficacy, decrease adverse side effects, or overcome drug resistance. Given the enormous number of drug combinations, it is cost- and…

分子网络 · 定量生物学 2021-02-18 Peiran Jiang , Shujun Huang , Zhenyuan Fu , Zexuan Sun , Ted M. Lakowski , Pingzhao Hu

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Deep learning for regression tasks on medical imaging data has shown promising results. However, compared to other approaches, their power is strongly linked to the dataset size. In this study, we evaluate 3D-convolutional neural networks…

计算机视觉与模式识别 · 计算机科学 2018-11-13 Yannick Suter , Alain Jungo , Michael Rebsamen , Urspeter Knecht , Evelyn Herrmann , Roland Wiest , Mauricio Reyes

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

Cancer is one of the leading causes of death globally, and early diagnosis is crucial for patient survival. Deep learning algorithms have great potential for automatic cancer analysis. Artificial intelligence has achieved high performance…

图像与视频处理 · 电气工程与系统科学 2024-04-16 Monika Górka , Daniel Jaworek , Marek Wodzinski

Skin cancer is a life-threatening disease where early detection significantly improves patient outcomes. Automated diagnosis from dermoscopic images is challenging due to high intra-class variability and subtle inter-class differences. Many…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Md. Enamul Atiq , Shaikh Anowarul Fattah

Deep learning (DL) models have received particular attention in medical imaging due to their promising pattern recognition capabilities. However, Deep Neural Networks (DNNs) require a huge amount of data, and because of the lack of…

图像与视频处理 · 电气工程与系统科学 2021-07-27 Donya Khaledyan , AmirReza Tajally , Ali Sarkhosh , Afshar Shamsi , Hamzeh Asgharnezhad , Abbas Khosravi , Saeid Nahavandi

Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has…

计算机视觉与模式识别 · 计算机科学 2020-06-11 Sunghwan Yoo , Isha Gujrathi , Masoom A. Haider , Farzad Khalvati

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

机器学习 · 统计学 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

计算机视觉与模式识别 · 计算机科学 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

This study addresses critical gaps in automated lymphoma segmentation from PET/CT images, focusing on issues often overlooked in existing literature. While deep learning has been applied for lymphoma lesion segmentation, few studies…

This paper introduces feature gradient flow, a new technique for interpreting deep learning models in terms of features that are understandable to humans. The gradient flow of a model locally defines nonlinear coordinates in the input data…

图像与视频处理 · 电气工程与系统科学 2023-07-26 Yinzhu Jin , Jonathan C. Garneau , P. Thomas Fletcher

The clinical integration of deep learning models for brain tumor diagnosis in neuro-oncology is severely constrained by limited expert-annotated MRI data and substantial inter-institutional domain shift arising from variations in scanners,…

计算机视觉与模式识别 · 计算机科学 2026-05-06 Sapna Sachan , Amulya Kumar Mahto , Prashant Wagambar Patil