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A crucial aspect of managing a public health crisis is to effectively balance prevention and mitigation strategies, while taking their socio-economic impact into account. In particular, determining the influence of different…

Epidemics such as COVID-19 pose serious threats to public health and our society, and it is critical to investigate effective methods to control the spread of epidemics over networks. Prior works on epidemic control often assume complete…

人工智能 · 计算机科学 2023-10-13 Wenxiang Dong , Zhanjiang Chen , H. Vicky Zhao

Achieving safe and coordinated behavior in dynamic, constraint-rich environments remains a major challenge for learning-based control. Pure end-to-end learning often suffers from poor sample efficiency and limited reliability, while…

系统与控制 · 电气工程与系统科学 2025-10-10 Max Studt , Georg Schildbach

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

种群与进化 · 定量生物学 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

Restless multi-armed bandits (RMABs) provide a scalable framework for sequential decision-making under uncertainty, but classical formulations assume binary actions and a single global budget. Real-world settings, such as healthcare, often…

机器学习 · 计算机科学 2025-10-28 Himadri S. Pandey , Kai Wang , Gian-Gabriel P. Garcia

Combating an epidemic entails finding a plan that describes when and how to apply different interventions, such as mask-wearing mandates, vaccinations, school or workplace closures. An optimal plan will curb an epidemic with minimal loss of…

机器学习 · 计算机科学 2023-06-08 Anh Mai , Nikunj Gupta , Azza Abouzied , Dennis Shasha

Although High Performance Computing (HPC) users understand basic resource requirements such as the number of CPUs and memory limits, internal infrastructural utilization data is exclusively leveraged by cluster operators, who use it to…

分布式、并行与集群计算 · 计算机科学 2024-01-19 Abel Souza , Kristiaan Pelckmans , Johan Tordsson

Appropriate medication dosages in the intensive care unit (ICU) are critical for patient survival. Heparin, used to treat thrombosis and inhibit blood clotting in the ICU, requires careful administration due to its complexity and…

机器学习 · 计算机科学 2025-12-09 Yooseok Lim , Inbeom Park , Sujee Lee

Non-pharmaceutical interventions (NPIs) are crucial for controlling pandemics, but existing research often overlooks the heterogeneity of individual behavior, which can lead to inaccurate evaluations of the effectiveness of strategies. In…

物理与社会 · 物理学 2026-03-09 Xihan Zhang , Yuqing Liu , Chen Zhao , Guijun Li

Facing a global epidemic of new infectious diseases such as COVID-19, non-pharmaceutical interventions (NPIs), which reduce transmission rates without medical actions, are being implemented around the world to mitigate spreads. One of the…

种群与进化 · 定量生物学 2021-03-04 Naoya Fujiwara , Tomokatsu Onaga , Takayuki Wada , Shouhei Takeuchi , Junji Seto , Tomoki Nakaya , Kazuyuki Aihara

We study how to effectively leverage expert feedback to learn sequential decision-making policies. We focus on problems with sparse rewards and long time horizons, which typically pose significant challenges in reinforcement learning. We…

机器学习 · 计算机科学 2018-06-12 Hoang M. Le , Nan Jiang , Alekh Agarwal , Miroslav Dudík , Yisong Yue , Hal Daumé

Nonlinear optimal control problems are often solved with numerical methods that require knowledge of system's dynamics which may be difficult to infer, and that carry a large computational cost associated with iterative calculations. We…

机器学习 · 计算机科学 2019-03-08 Ekaterina Abramova , Luke Dickens , Daniel Kuhn , Aldo Faisal

Budget planning and maintenance optimization are crucial for infrastructure asset management, ensuring cost-effectiveness and sustainability. However, the complexity arising from combinatorial action spaces, diverse asset deterioration,…

人工智能 · 计算机科学 2025-07-28 Amir Fard , Arnold X. -X. Yuan

This paper introduces a novel data-driven hierarchical control scheme for managing a fleet of nonlinear, capacity-constrained autonomous agents in an iterative environment. We propose a control framework consisting of a high-level dynamic…

机器人学 · 计算机科学 2024-04-12 Charlott Vallon , Alessandro Pinto , Bartolomeo Stellato , Francesco Borrelli

This work presents a Hierarchical Multi-Agent Reinforcement Learning framework for analyzing simulated air combat scenarios involving heterogeneous agents. The objective is to identify effective Courses of Action that lead to mission…

The outbreak of COVID-19 has highlighted the intricate interplay between public health and economic stability on a global scale. This study proposes a novel reinforcement learning framework designed to optimize health and economic outcomes…

机器学习 · 计算机科学 2024-05-01 Maeghal Jain , Ziya Uddin , Wubshet Ibrahim

In the absence of drugs and vaccines, policymakers use non-pharmaceutical interventions such as social distancing to decrease rates of disease-causing contact, with the aim of reducing or delaying the epidemic peak. These measures carry…

种群与进化 · 定量生物学 2021-04-22 Dylan H. Morris , Fernando W. Rossine , Joshua B. Plotkin , Simon A. Levin

This paper considers the problem of designing non-pharmaceutical intervention (NPI) strategies, such as masking and social distancing, to slow the spread of a viral epidemic. We formulate the problem of jointly minimizing the infection…

系统与控制 · 电气工程与系统科学 2024-12-02 Shiyu Cheng , Luyao Niu , Bhaskar Ramasubramanian , Andrew Clark , Radha Poovendran

Decision-making in complex, continuous multi-task environments is often hindered by the difficulty of obtaining accurate models for planning and the inefficiency of learning purely from trial and error. While precise environment dynamics…

机器学习 · 计算机科学 2025-03-20 Jeff Jewett , Sandhya Saisubramanian

We propose a new approach for solving planning problems with a hierarchical structure, fusing reinforcement learning and MPC planning. Our formulation tightly and elegantly couples the two planning paradigms. It leverages reinforcement…

机器学习 · 计算机科学 2026-04-17 Toshiaki Hori , Jonathan DeCastro , Deepak Gopinath , Avinash Balachandran , Guy Rosman
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