相关论文: Multimodal Model for Computational Pathology:Repre…
Survival prediction, utilizing pathological images and genomic profiles, is increasingly important in cancer analysis and prognosis. Despite significant progress, precise survival analysis still faces two main challenges: (1) The massive…
Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of…
In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…
Representation learning from Gigapixel Whole Slide Images (WSI) poses a significant challenge in computational pathology due to the complicated nature of tissue structures and the scarcity of labeled data. Multi-instance learning methods…
Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…
Recent advances in vision-language models (VLMs) have shown remarkable potential in bridging visual and textual modalities. In computational pathology, domain-specific VLMs, which are pre-trained on extensive histopathology image-text…
The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…
Digitized histopathology glass slides, known as Whole Slide Images (WSIs), are often several gigapixels large and contain sensitive metadata information, which makes distributed processing unfeasible. Moreover, artifacts in WSIs may result…
Whole slide images (WSIs) enable weakly supervised prognostic modeling via multiple instance learning (MIL). Spatial transcriptomics (ST) preserves in situ gene expression, providing a spatial molecular context that complements morphology.…
A crucial step to efficiently integrate Whole Slide Images (WSIs) in computational pathology is assigning a single high-quality feature vector, i.e., one embedding, to each WSI. With the existence of many pre-trained deep neural networks…
Whole-slide images (WSIs) in pathology can reach up to 10,000 x 10,000 pixels, posing significant challenges for multimodal large language model (MLLM) due to long context length and high computational demands. Previous methods typically…
From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…
Deploying digital pathology models across medical centers is challenging due to distribution shifts. Recent advances in domain generalization improve model transferability in terms of aggregated performance measured by the Area Under Curve…
Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…
Diagnosing a whole-slide image is an interactive, multi-stage process of changing magnification and moving between fields. Although recent pathology foundation models demonstrated superior performances, practical agentic systems that decide…
Deep convolutional neural networks (CNNs) are the current state-of-the-art for digital analysis of histopathological images. The large size of whole-slide microscopy images (WSIs) requires advanced memory handling to read, display and…
Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…
Advancement in digital pathology and artificial intelligence has enabled deep learning-based computer vision techniques for automated disease diagnosis and prognosis. However, WSIs present unique computational and algorithmic challenges.…
This paper presents an autoencoder-based neural network architecture to compress histopathological images while retaining the denser and more meaningful representation of the original images. Current research into improving compression…
While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generalization problems due to challenges in high computational…