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Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

计算机视觉与模式识别 · 计算机科学 2019-11-25 Tianyang Zhang , Rui Ma

Deep learning has excelled in medical image classification, but its clinical application is limited by poor interpretability. Capsule networks, known for encoding hierarchical relationships and spatial features, show potential in addressing…

计算机视觉与模式识别 · 计算机科学 2024-11-05 Xinyu Geng , Jiaming Wang , Jun Xu

Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Structures are not known for the vast majority of protein sequences, but structure is critical for…

机器学习 · 计算机科学 2019-10-17 Tristan Bepler , Bonnie Berger

Tables are information-rich structured objects in document images. While significant work has been done in localizing tables as graphic objects in document images, only limited attempts exist on table structure recognition. Most existing…

计算机视觉与模式识别 · 计算机科学 2020-10-12 Sachin Raja , Ajoy Mondal , C. V. Jawahar

Classification of proteins based on their structure provides a valuable resource for studying protein structure, function and evolutionary relationships. With the rapidly increasing number of known protein structures, manual and…

计算工程、金融与科学 · 计算机科学 2009-07-14 Oktie Hassanzadeh

Cellular nuclei recognition serves as a fundamental and essential step in the workflow of digital pathology. However, with disparate source organs and staining procedures among histology image clusters, the scanned tiles inherently conform…

定量方法 · 定量生物学 2024-07-22 Jianan Fan , Dongnan Liu , Canran Li , Hang Chang , Heng Huang , Filip Braet , Mei Chen , Weidong Cai

Microscopy images contain rich information about how cells respond to perturbations, making them essential to applications like drug screening. To quantify images, researchers often use representation extraction methods, and recent years…

计算机视觉与模式识别 · 计算机科学 2026-05-18 Emre Hayir , Lorin Crawford , Alex X. Lu

Place recognition is a key module in robotic navigation. The existing line of studies mostly focuses on visual place recognition to recognize previously visited places solely based on their appearance. In this paper, we address structural…

机器人学 · 计算机科学 2021-09-29 Giseop Kim , Sunwook Choi , Ayoung Kim

Proteins are biomolecules of life. They fold into a great variety of three-dimensional (3D) shapes. Underlying these folding patterns are many recurrent structural fragments or building blocks (analogous to `LEGO bricks'). This paper…

定量方法 · 定量生物学 2013-10-08 Arun S. Konagurthu , Arthur M. Lesk , David Abramson , Peter J. Stuckey , Lloyd Allison

Face segmentation is the task of densely labeling pixels on the face according to their semantics. While current methods place an emphasis on developing sophisticated architectures, use conditional random fields for smoothness, or rather…

计算机视觉与模式识别 · 计算机科学 2020-03-31 Iacopo Masi , Joe Mathai , Wael AbdAlmageed

The success of machine learning in drug discovery hinges on learning the relationship between a chemical structure and its biological activity. While DNA-Encoded Library (DEL) technology can generate the massive datasets required for this…

生物大分子 · 定量生物学 2026-05-11 Mutian He , Hanqun Cao , Cheng Tan , Zijun Gao , Xiaojun Yao , Chunbin Gu , Pheng-Ann Heng

Understanding the structure of a protein complex is crucial indetermining its function. However, retrieving accurate 3D structures from microscopy images is highly challenging, particularly as many imaging modalities are two-dimensional.…

定量方法 · 定量生物学 2021-10-18 Benjamin J. Blundell , Christian Sieben , Suliana Manley , Ed Rosten , QueeLim Ch'ng , Susan Cox

Segmentation of brain magnetic resonance images (MRI) is crucial for the analysis of the human brain and diagnosis of various brain disorders. The drawbacks of time-consuming and error-prone manual delineation procedures are aimed to be…

计算机视觉与模式识别 · 计算机科学 2022-05-20 Can Taylan Sari , Sila Kurugol , Onur Afacan , Simon K. Warfield

Given the ubiquitous existence of graph-structured data, learning the representations of nodes for the downstream tasks ranging from node classification, link prediction to graph classification is of crucial importance. Regarding missing…

机器学习 · 计算机科学 2022-04-21 Bisheng Li , Min Zhou , Shengzhong Zhang , Menglin Yang , Defu Lian , Zengfeng Huang

A crystallographic cell is a representation of a lattice, but each lattice can be represented just as well by any of an infinite number of such unit cells. Searching for matches to an experimentally determined crystallographic unit cell in…

Histopathology image analysis plays a crucial role in cancer diagnosis. However, training a clinically applicable segmentation algorithm requires pathologists to engage in labour-intensive labelling. In contrast, weakly supervised learning…

计算机视觉与模式识别 · 计算机科学 2024-05-28 Gang Xu , Shuhao Wang , Lingyu Zhao , Xiao Chen , Tongwei Wang , Lang Wang , Zhenwei Luo , Dahan Wang , Zewen Zhang , Aijun Liu , Wei Ba , Zhigang Song , Huaiyin Shi , Dingrong Zhong , Jianpeng Ma

In recent years, there has been a surge in the development of 3D structure-based pre-trained protein models, representing a significant advancement over pre-trained protein language models in various downstream tasks. However, most existing…

机器学习 · 计算机科学 2024-06-04 Jiale Zhao , Wanru Zhuang , Jia Song , Yaqi Li , Shuqi Lu

Learning from 3D protein structures has gained wide interest in protein modeling and structural bioinformatics. Unfortunately, the number of available structures is orders of magnitude lower than the training data sizes commonly used in…

生物大分子 · 定量生物学 2022-06-01 Pedro Hermosilla , Timo Ropinski

Graph-based learning is a cornerstone for analyzing structured data, with node classification as a central task. However, in many real-world graphs, nodes lack informative feature vectors, leaving only neighborhood connectivity and class…

机器学习 · 计算机科学 2025-10-14 Sujan Chakraborty , Rahul Bordoloi , Anindya Sengupta , Olaf Wolkenhauer , Saptarshi Bej

Deep learning networks have shown promising performance for accurate object localization in medial images, but require large amount of annotated data for supervised training, which is expensive and expertise burdensome. To address this…

计算机视觉与模式识别 · 计算机科学 2021-05-26 Wenhui Lei , Wei Xu , Ran Gu , Hao Fu , Shaoting Zhang , Guotai Wang