相关论文: Sample-Efficient Adaptation of Drug-Response Model…

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

We present an approach to domain adaptation, addressing the case where data from the source domain is abundant, labelled data from the target domain is limited or non-existent, and a small amount of paired source-target data is available.…

The accurate prediction of drug responses remains a formidable challenge, particularly at the single-cell level and in clinical treatment contexts. Some studies employ transfer learning techniques to predict drug responses in individual…

Domain shift is a significant challenge in machine learning, particularly in medical applications where data distributions differ across institutions due to variations in data collection practices, equipment, and procedures. This can…

Accurate and robust drug response prediction is of utmost importance in precision medicine. Although many models have been developed to utilize the representations of drugs and cancer cell lines for predicting cancer drug responses (CDR),…

This paper investigates the critical problem of representation similarity evolution during cross-domain transfer learning, with particular focus on understanding why pre-trained models maintain effectiveness when adapted to medical imaging…

Pretrained language models have shown success in various areas of natural language processing, including reading comprehension tasks. However, when applying machine learning methods to new domains, labeled data may not always be available.…

Models capable of leveraging unlabelled data are crucial in overcoming large distribution gaps between the acquired datasets across different imaging devices and configurations. In this regard, self-training techniques based on…

We study the prediction of T-cell response for specific given peptides, which could, among other applications, be a crucial step towards the development of personalized cancer vaccines. It is a challenging task due to limited, heterogeneous…

We consider the novel problem of unsupervised domain adaptation of source models, without access to the source data for semantic segmentation. Unsupervised domain adaptation aims to adapt a model learned on the labeled source data, to a new…

Accurate phenotype prediction from RNA sequencing (RNA-seq) data is essential for diagnosis, biomarker discovery, and personalized medicine. Deep learning models have demonstrated strong potential to outperform classical machine learning…

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Unsupervised domain adaptation aims to address the problem of classifying unlabeled samples from the target domain whilst labeled samples are only available from the source domain and the data distributions are different in these two…

Large-scale labeled training datasets have enabled deep neural networks to excel on a wide range of benchmark vision tasks. However, in many applications it is prohibitively expensive or time-consuming to obtain large quantities of labeled…

Studies show that the representations learned by deep neural networks can be transferred to similar prediction tasks in other domains for which we do not have enough labeled data. However, as we transition to higher layers in the model, the…

In this paper, we consider the problem of learning a linear regression model on a data domain of interest (target) given few samples. To aid learning, we are provided with a set of pre-trained regression models that are trained on…

The advancement of single-cell sequencing technology has promoted the generation of a large amount of single-cell transcriptional profiles, providing unprecedented opportunities to identify drug-resistant cell subpopulations within a tumor.…

High-throughput screening technology has facilitated the generation of large-scale drug responses across hundreds of cancer cell lines. However, there exists significant discrepancy between in vitro cell lines and actual tumors in vivo in…

The assumption that training and testing samples are generated from the same distribution does not always hold for real-world machine-learning applications. The procedure of tackling this discrepancy between the training (source) and…

Most approaches in few-shot learning rely on costly annotated data related to the goal task domain during (pre-)training. Recently, unsupervised meta-learning methods have exchanged the annotation requirement for a reduction in few-shot…