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Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

计算与语言 · 计算机科学 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

Objective: Large Language Models (LLMs) demonstrate significant capabilities in medical text understanding and generation. However, their diagnostic reliability in complex clinical scenarios remains limited. This study aims to enhance LLMs'…

计算与语言 · 计算机科学 2025-08-04 Peixian Li , Yu Tian , Ruiqi Tu , Chengkai Wu , Jingjing Ren , Jingsong Li

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

计算与语言 · 计算机科学 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Large Language Models (LLMs) are increasingly utilized for mental health support; however, current safety benchmarks often fail to detect the complex, longitudinal risks inherent in therapeutic dialogue. We introduce an evaluation framework…

计算与语言 · 计算机科学 2026-03-06 Ian Steenstra , Paola Pedrelli , Weiyan Shi , Stacy Marsella , Timothy W. Bickmore

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

人工智能 · 计算机科学 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

计算与语言 · 计算机科学 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

While large language models (LLMs) have shown promise in diagnostic dialogue, their capabilities for effective management reasoning - including disease progression, therapeutic response, and safe medication prescription - remain…

Large Language Models (LLMs) are increasingly used in healthcare, yet ensuring their safety and trustworthiness remains a barrier to deployment. Conversational medical assistants must avoid unsafe compliance without over-refusing benign…

人工智能 · 计算机科学 2025-12-05 Huy Nghiem , Swetasudha Panda , Devashish Khatwani , Huy V. Nguyen , Krishnaram Kenthapadi , Hal Daumé

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

人工智能 · 计算机科学 2025-01-27 Arjun R. Malghan

Intensive care units (ICU) generate long, dense and evolving streams of clinical information, where physicians must repeatedly reassess patient states under time pressure, underscoring a clear need for reliable AI decision support. Existing…

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

We introduce a multi-turn benchmark for evaluating personalised alignment in LLM-based AI assistants, focusing on their ability to handle user-provided safety-critical contexts. Our assessment of ten leading models across five scenarios…

人机交互 · 计算机科学 2025-01-31 Lize Alberts , Benjamin Ellis , Andrei Lupu , Jakob Foerster

LLMs are popular among clinicians for decision-support because of simple text-based interaction. However, their impact on clinicians' performance is ambiguous. Not knowing how clinicians use this new technology and how they compare it to…

人机交互 · 计算机科学 2026-02-02 Behnam Rahdari , Sameer Shaikh , Jonathan H Chen , Tobias Gerstenberg , Shriti Raj

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the…

计算与语言 · 计算机科学 2024-04-30 Yubin Kim , Xuhai Xu , Daniel McDuff , Cynthia Breazeal , Hae Won Park

As large language models (LLMs) become progressively more embedded in clinical decision-support, documentation, and patient-information systems, ensuring their privacy and trustworthiness has emerged as an imperative challenge for the…

密码学与安全 · 计算机科学 2025-10-22 Alexander Nemecek , Zebin Yun , Zahra Rahmani , Yaniv Harel , Vipin Chaudhary , Mahmood Sharif , Erman Ayday

A decade of rapid advances in artificial intelligence (AI) has opened new opportunities for clinical decision support systems (CDSS), with large language models (LLMs) demonstrating strong reasoning abilities on timely medical tasks.…

计算与语言 · 计算机科学 2025-11-25 Heejoon Koo

Large Language Models (LLMs) have attained human-level accuracy on medical question-answer (QA) benchmarks. However, their limitations in navigating open-ended clinical scenarios have recently been shown, raising concerns about the…

计算与语言 · 计算机科学 2025-11-13 Jonathan Kim , Anna Podlasek , Kie Shidara , Feng Liu , Ahmed Alaa , Danilo Bernardo

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

计算与语言 · 计算机科学 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang