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As deep learning models increasingly find applications in critical domains such as medical imaging, the need for transparent and trustworthy decision-making becomes paramount. Many explainability methods provide insights into how these…

计算机视觉与模式识别 · 计算机科学 2023-11-09 Piotr Komorowski , Hubert Baniecki , Przemysław Biecek

Radiographs are a versatile diagnostic tool for the detection and assessment of pathologies, for treatment planning or for navigation and localization purposes in clinical interventions. However, their interpretation and assessment by…

计算机视觉与模式识别 · 计算机科学 2022-08-18 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

计算机视觉与模式识别 · 计算机科学 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

Biopsies are the gold standard for breast cancer diagnosis. This task can be improved by the use of Computer Aided Diagnosis (CAD) systems, reducing the time of diagnosis and reducing the inter and intra-observer variability. The advances…

计算机视觉与模式识别 · 计算机科学 2019-05-30 Jonathan de Matos , Alceu de S. Britto , Luiz E. S. de Oliveira , Alessandro L. Koerich

Transformers, due to their ability to learn long range dependencies, have overcome the shortcomings of convolutional neural networks (CNNs) for global perspective learning. Therefore, they have gained the focus of researchers for several…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Momina Liaqat Ali , Zunaira Rauf , Asifullah Khan , Anabia Sohail , Rafi Ullah , Jeonghwan Gwak

Definitive cancer diagnosis and management depend upon the extraction of information from microscopy images by pathologists. These images contain complex information requiring time-consuming expert human interpretation that is prone to…

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

图像与视频处理 · 电气工程与系统科学 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Breast-conserving surgery (BCS) aims to completely remove malignant lesions while maximizing healthy tissue preservation. Intraoperative margin assessment is essential to achieve a balance between thorough cancer resection and tissue…

图像与视频处理 · 电气工程与系统科学 2026-01-16 Pouya Afshin , David Helminiak , Tongtong Lu , Tina Yen , Julie M. Jorns , Mollie Patton , Bing Yu , Dong Hye Ye

Diagnostic pathology, which is the basis and gold standard of cancer diagnosis, provides essential information on the prognosis of the disease and vital evidence for clinical treatment. Tumor region detection, subtype and grade…

图像与视频处理 · 电气工程与系统科学 2021-10-27 Jialun Wu , Haichuan Zhang , Zeyu Gao , Xinrui Bao , Tieliang Gong , Chunbao Wang , Chen Li

According to some medical imaging techniques, breast histopathology images called Hematoxylin and Eosin are considered as the gold standard for cancer diagnoses. Based on the idea of dividing the pathologic image (WSI) into multiple…

图像与视频处理 · 电气工程与系统科学 2022-07-13 Tat-Bao-Thien Nguyen , Minh-Vuong Ngo , Van-Phong Nguyen

Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

计算机视觉与模式识别 · 计算机科学 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

Accurate classification of breast cancer histopathology images is pivotal for early oncological diagnosis and therapeutic intervention.However, conventional deep learning architectures often encounter performance degradation under limited…

计算机视觉与模式识别 · 计算机科学 2026-02-11 Lin-Guo Gao , Suxing Liu

Pathological images play an essential role in cancer prognosis, while survival analysis, which integrates computational techniques, can predict critical clinical events such as patient mortality or disease recurrence from whole-slide images…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Guo Tang , Songhan Jiang , Jinpeng Lu , Linghan Cai , Yongbing Zhang

For many patients, current ovarian cancer treatments offer limited clinical benefit. For some therapies, it is not possible to predict patients' responses, potentially exposing them to the adverse effects of treatment without any…

图像与视频处理 · 电气工程与系统科学 2023-10-20 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nishant Ravikumar , Nicolas M. Orsi

Histopathology is a reflection of the molecular changes and provides prognostic phenotypes representing the disease progression. In this study, we introduced feature scores generated from hematoxylin and eosin histology images based on deep…

Background and purpose: Colorectal cancer has become the third most common cancer worldwide, accounting for approximately 10% of cancer patients. Early detection of the disease is important for the treatment of colorectal cancer patients.…

图像与视频处理 · 电气工程与系统科学 2022-02-18 Weiming Hu , Chen Li , Xiaoyan Li , Md Mamunur Rahaman , Yong Zhang , Haoyuan Chen , Wanli Liu , Yudong Yao , Hongzan Sun , Ning Xu , Xinyu Huang , Marcin Grzegorze

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

图像与视频处理 · 电气工程与系统科学 2022-10-18 Yuzhe Lu , Adam Perer

In the medical field, accurate diagnosis of lung cancer is crucial for treatment. Traditional manual analysis methods have significant limitations in terms of accuracy and efficiency. To address this issue, this paper proposes a deep…

图像与视频处理 · 电气工程与系统科学 2025-01-10 Ziyang Gao , Yong Tian , Shih-Chi Lin , Junghua Lin

Nuclei detection and segmentation in hematoxylin and eosin-stained (H&E) tissue images are important clinical tasks and crucial for a wide range of applications. However, it is a challenging task due to nuclei variances in staining and…

图像与视频处理 · 电气工程与系统科学 2023-10-09 Fabian Hörst , Moritz Rempe , Lukas Heine , Constantin Seibold , Julius Keyl , Giulia Baldini , Selma Ugurel , Jens Siveke , Barbara Grünwald , Jan Egger , Jens Kleesiek