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Electronic health record (EHR) systems present clinicians with vast repositories of clinical information, creating a significant cognitive burden where critical details are easily overlooked. While Large Language Models (LLMs) offer…

计算与语言 · 计算机科学 2026-03-17 Samuel Thio , Matthew Lewis , Spiros Denaxas , Richard JB Dobson

Large language models (LLMs) excel in generating fluent utterances but can lack reliable grounding in verified information. At the same time, knowledge-graph-based fact-checkers deliver precise and interpretable evidence, yet suffer from…

计算与语言 · 计算机科学 2025-11-06 Shaghayegh Kolli , Richard Rosenbaum , Timo Cavelius , Lasse Strothe , Andrii Lata , Jana Diesner

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

人工智能 · 计算机科学 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Large language models (LLMs) are increasingly used in the mental health domain, yet it remains unclear how well they capture related biomedical knowledge and how reliably they apply it to clinically salient structured judgments. Here, we…

Data protection and privacy is becoming increasingly crucial in the digital era. Numerous companies depend on third-party vendors and service providers to carry out critical functions within their operations, encompassing tasks such as data…

密码学与安全 · 计算机科学 2025-08-25 Leon Garza , Lavanya Elluri , Anantaa Kotal , Aritran Piplai , Deepti Gupta , Anupam Joshi

Modern scientific discovery faces growing challenges in integrating vast and heterogeneous knowledge critical to breakthroughs in biomedicine and drug development. Traditional hypothesis-driven research, though effective, is constrained by…

人机交互 · 计算机科学 2025-07-24 Haoran Jiang , Shaohan Shi , Yunjie Yao , Chang Jiang , Quan Li

This study explores the use of Large Language Models (LLMs) for automatic evaluation of knowledge graph (KG) completion models. Historically, validating information in KGs has been a challenging task, requiring large-scale human annotation…

Accurate interpretation of pediatric dental clinical records and safe antibiotic prescribing remain persistent challenges in dental informatics. Traditional rule-based clinical decision support systems struggle with unstructured dental…

计算与语言 · 计算机科学 2025-12-11 Zihan Han , Junyan Ge , Caifeng Li

Verifying the complex and multi-step reasoning of Large Language Models (LLMs) is a critical challenge, as holistic methods often overlook localized flaws. Step-by-step validation is a promising alternative, yet existing methods are often…

人工智能 · 计算机科学 2025-11-25 Jiwei Fang , Bin Zhang , Changwei Wang , Jin Wan , Zhiwei Xu

Large Language Models (LLMs) show promise as planners for embodied AI, but their stochastic nature lacks formal reasoning, preventing strict safety guarantees for physical deployment. Current approaches often rely on unreliable LLMs for…

人工智能 · 计算机科学 2026-04-30 Feiyu Wu , Xu Zheng , Yue Qu , Zhuocheng Wang , Zicheng Feng , Hui Li

Knowledge graphs and large language models (LLMs) are key tools for biomedical knowledge integration and reasoning, facilitating structured organization of scientific articles and discovery of complex semantic relationships. However,…

计算与语言 · 计算机科学 2025-04-01 Yichun Feng , Jiawei Wang , Ruikun He , Lu Zhou , Yixue Li

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

The synergy between symbolic knowledge, often represented by Knowledge Graphs (KGs), and the generative capabilities of neural networks is central to advancing neurosymbolic AI. A primary bottleneck in realizing this potential is the…

机器学习 · 计算机科学 2025-07-24 Adrian Kaiser , Claudiu Leoveanu-Condrei , Ryan Gold , Marius-Constantin Dinu , Markus Hofmarcher

Integrating knowledge graphs (KGs) to enhance the reasoning capabilities of large language models (LLMs) is an emerging research challenge in claim verification. While KGs provide structured, semantically rich representations well-suited…

计算与语言 · 计算机科学 2025-05-29 Hoang Pham , Thanh-Do Nguyen , Khac-Hoai Nam Bui

The recent proliferation of large language models (LLMs) holds the potential to revolutionize healthcare, with strong capabilities in diverse medical tasks. Yet, deploying LLMs in high-stakes healthcare settings requires rigorous…

机器学习 · 计算机科学 2025-12-22 Shasha Zhou , Mingyu Huang , Jack Cole , Charles Britton , Ming Yin , Jan Wolber , Ke Li

In this paper, we investigate the retrieval-augmented generation (RAG) based on Knowledge Graphs (KGs) to improve the accuracy and reliability of Large Language Models (LLMs). Recent approaches suffer from insufficient and repetitive…

计算与语言 · 计算机科学 2024-04-22 Xinke Jiang , Ruizhe Zhang , Yongxin Xu , Rihong Qiu , Yue Fang , Zhiyuan Wang , Jinyi Tang , Hongxin Ding , Xu Chu , Junfeng Zhao , Yasha Wang

Large Language Models (LLMs) have demonstrated remarkable capabilities in text generation and understanding, yet their reliance on implicit, unstructured knowledge often leads to factual inaccuracies and limited interpretability. Knowledge…

计算与语言 · 计算机科学 2025-06-17 Qinggang Zhang

Adverse Drug Reactions (ADRs) are a leading cause of morbidity and mortality. Existing prediction methods rely mainly on chemical similarity, machine learning on structured databases, or isolated target profiles, but often fail to integrate…

生物大分子 · 定量生物学 2026-03-03 David Jackson , Michael Gertz , Jürgen Hesser

Advancements in natural language processing have revolutionized the way we can interact with digital information systems, such as databases, making them more accessible. However, challenges persist, especially when accuracy is critical, as…

计算与语言 · 计算机科学 2025-11-12 Larissa Pusch , Tim O. F. Conrad
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