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Early and accurate detection of Alzheimer's disease (AD) is crucial for enabling timely intervention and improving outcomes. However, developing reliable machine learning (ML) models for AD diagnosis is challenging due to limited labeled…

机器学习 · 计算机科学 2025-11-27 Abolfazl Moslemi , Hossein Peyvandi

Generative modeling frameworks have emerged as an effective approach to capture high-dimensional image distributions from large datasets without requiring domain-specific knowledge, a capability essential for longitudinal disease…

计算机视觉与模式识别 · 计算机科学 2025-11-11 Ayantika Das , Arunima Sarkar , Keerthi Ram , Mohanasankar Sivaprakasam

This paper presents StrADiff, a Structured Source-Wise Adaptive Diffusion Framework for unsupervised blind source separation under linear and nonlinear mixing. The framework treats each latent dimension as a source branch and assigns to it…

机器学习 · 统计学 2026-04-29 Yuan-Hao Wei

With the rapid development of imaging sensor technology in the field of remote sensing, multi-modal remote sensing data fusion has emerged as a crucial research direction for land cover classification tasks. While diffusion models have made…

计算机视觉与模式识别 · 计算机科学 2024-01-08 DaiXun Li , Weiying Xie , ZiXuan Wang , YiBing Lu , Yunsong Li , Leyuan Fang

Mild Cognitive Impairment (MCI) serves as a prodromal stage of Alzheimer's Disease (AD), where early identification and intervention can effectively slow the progression to dementia. However, diagnosing AD remains a significant challenge in…

人工智能 · 计算机科学 2025-11-07 Yutao Jin , Haowen Xiao , Junyong Zhai , Yuxiao Li , Jielei Chu , Fengmao Lv , Yuxiao Li

Objective: The study aims to address the challenge of aligning Standard Fundus Images (SFIs) and Ultra-Widefield Fundus Images (UWFIs), which is difficult due to their substantial differences in viewing range and the amorphous appearance of…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Kanggeon Lee , Su Jeong Song , Soochahn Lee , Kyoung Mu Lee

In the field of behavior-related brain computation, it is necessary to align raw neural signals against the drastic domain shift among them. A foundational framework within neuroscience research posits that trial-based neural population…

神经元与认知 · 定量生物学 2024-03-12 Yule Wang , Zijing Wu , Chengrui Li , Anqi Wu

Multimodal medical image fusion (MMIF) extracts the most meaningful information from multiple source images, enabling a more comprehensive and accurate diagnosis. Achieving high-quality fusion results requires a careful balance of…

计算机视觉与模式识别 · 计算机科学 2025-06-19 Dan He , Weisheng Li , Guofen Wang , Yuping Huang , Shiqiang Liu

Medical image segmentation has been significantly advanced with the rapid development of deep learning (DL) techniques. Existing DL-based segmentation models are typically discriminative; i.e., they aim to learn a mapping from the input…

计算机视觉与模式识别 · 计算机科学 2025-09-01 Tao Chen , Chenhui Wang , Zhihao Chen , Yiming Lei , Hongming Shan

The integration of pathologic images and genomic data for survival analysis has gained increasing attention with advances in multimodal learning. However, current methods often ignore biological characteristics, such as heterogeneity and…

计算机视觉与模式识别 · 计算机科学 2025-03-28 Shuaiyu Zhang , Xun Lin , Rongxiang Zhang , Yu Bai , Yong Xu , Tao Tan , Xunbin Zheng , Zitong Yu

Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are…

Positron emission tomography (PET) scans expose patients to radiation, which can be mitigated by reducing the dose, albeit at the cost of diminished quality. This makes low-dose (LD) PET recovery an active research area. Previous studies…

图像与视频处理 · 电气工程与系统科学 2026-03-11 Ghulam Nabi Ahmad Hassan Yar , Himashi Peiris , Victoria Mar , Cameron Dennis Pain , Zhaolin Chen

Dynamic functional connectivity (dFC) using resting-state functional magnetic resonance imaging (rs-fMRI) is an advanced technique for capturing the dynamic changes of neural activities, and can be very useful in the studies of brain…

图像与视频处理 · 电气工程与系统科学 2025-01-29 Jing Zhang , Yanjun Lyu , Xiaowei Yu , Lu Zhang , Chao Cao , Tong Chen , Minheng Chen , Yan Zhuang , Tianming Liu , Dajiang Zhu

Early diagnosis of Alzheimer's disease (AD) remains a major challenge due to the subtle and temporally irregular progression of structural brain changes in the prodromal stages. Existing deep learning approaches require large longitudinal…

计算机视觉与模式识别 · 计算机科学 2026-02-10 Maxx Richard Rahman , Mostafa Hammouda , Wolfgang Maass

In the realm of neuroscience, identifying distinctive patterns associated with neurological disorders via brain networks is crucial. Resting-state functional magnetic resonance imaging (fMRI) serves as a primary tool for mapping these…

图像与视频处理 · 电气工程与系统科学 2025-10-27 Jiaxing Xu , Mengcheng Lan , Xia Dong , Kai He , Wei Zhang , Qingtian Bian , Yiping Ke

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

组织与器官 · 定量生物学 2026-04-17 Qianyu Chen , Shujian Yu

Given the audio-visual clip of the speaker, facial reaction generation aims to predict the listener's facial reactions. The challenge lies in capturing the relevance between video and audio while balancing appropriateness, realism, and…

计算机视觉与模式识别 · 计算机科学 2025-06-05 Jiaming Li , Sheng Wang , Xin Wang , Yitao Zhu , Honglin Xiong , Zixu Zhuang , Qian Wang

The integration of multimodal medical imaging can provide complementary and comprehensive information for the diagnosis of Alzheimer's disease (AD). However, in clinical practice, since positron emission tomography (PET) is often missing,…

计算工程、金融与科学 · 计算机科学 2024-12-03 Fuyou Mao , Lixin Lin , Ming Jiang , Dong Dai , Chao Yang , Hao Zhang , Yan Tang

Non-contrast CT (NCCT) imaging may reduce image contrast and anatomical visibility, potentially increasing diagnostic uncertainty. In contrast, contrast-enhanced CT (CECT) facilitates the observation of regions of interest (ROI). Leading…

图像与视频处理 · 电气工程与系统科学 2024-11-18 Tingyi Lin , Pengju Lyu , Jie Zhang , Yuqing Wang , Cheng Wang , Jianjun Zhu