相关论文: Reverse Distillation: Consistently Scaling Protein…

Retinal image matching plays a crucial role in monitoring disease progression and treatment response. However, datasets with matched keypoints between temporally separated pairs of images are not available in abundance to train…

Large Language Models (LLMs) have shown impressive results on a variety of text understanding tasks. Search queries though pose a unique challenge, given their short-length and lack of nuance or context. Complicated feature engineering…

Model distillation has emerged as a prominent technique to improve neural search models. To date, distillation taken an offline approach, wherein a new neural model is trained to predict relevance scores between arbitrary queries and…

Large Language Models (LLMs) enable advanced natural language processing but face deployment challenges on resource-constrained edge devices due to high computational, memory, and energy demands. Optimizing these models requires addressing…

With the exponential increase of the protein sequence databases over time, multiple-sequence alignment (MSA) methods, like PSI-BLAST, perform exhaustive and time-consuming database search to retrieve evolutionary information. The resulting…

Large language models (LLMs) have recently garnered significant interest. With in-context learning, LLMs achieve impressive results in various natural language tasks. However, the application of LLMs to sentence embeddings remains an area…

Word-embeddings are vital components of Natural Language Processing (NLP) models and have been extensively explored. However, they consume a lot of memory which poses a challenge for edge deployment. Embedding matrices, typically, contain…

Protein sequences are abundant in repeating segments, both as exact copies and as approximate segments with mutations. These repeats are important for protein structure and function, motivating decades of algorithmic work on repeat…

Embedding models are central to dense retrieval, semantic search, and recommendation systems, but their size often makes them impractical to deploy in resource-constrained environments such as browsers or edge devices. While smaller…

Recent work has shown that small distilled language models are strong competitors to models that are orders of magnitude larger and slower in a wide range of information retrieval tasks. This has made distilled and dense models, due to…

The emergence of Large Audio-Language Models (LALMs) has advanced Speech Emotion Recognition (SER), but their size limits deployment in resource-constrained environments. While Knowledge Distillation is effective for LALM compression,…

We consider the protein sequence engineering problem, which aims to find protein sequences with high fitness levels, starting from a given wild-type sequence. Directed evolution has been a dominating paradigm in this field which has an…

Dataset distillation aims to synthesize small datasets with little information loss from original large-scale ones for reducing storage and training costs. Recent state-of-the-art methods mainly constrain the sample synthesis process by…

Recent advances in Protein Language Models (PLMs) have transformed protein engineering, yet unlike their counterparts in Natural Language Processing (NLP), current PLMs exhibit a fundamental limitation: they excel in either Protein Language…

Protein language models (PLMs) learn probability distributions over natural protein sequences. By learning from hundreds of millions of natural protein sequences, protein understanding and design capabilities emerge. Recent works have shown…

Large language models (LLMs) have become increasingly prevalent in our daily lives, leading to an expectation for LLMs to be trustworthy -- - both accurate and well-calibrated (the prediction confidence should align with its ground truth…

Diffusion large language models (DLLMs) have emerged as powerful generative models with the promise of fast text generation through parallel decoding. However, realizing this potential in practice remains challenging: reducing the number of…

Large pre-trained language models often struggle to incorporate new domain-specific terminology when fine-tuned on small, specialized corpora. In this work, we address the challenge of vocabulary expansion in frozen LLMs by introducing a…

Accurate prediction of enzymatic activity from amino acid sequences could drastically accelerate enzyme engineering for applications such as bioremediation and therapeutics development. In recent years, Protein Language Model (PLM)…

Recent work has focused on compressing pre-trained language models (PLMs) like BERT where the major focus has been to improve the in-distribution performance for downstream tasks. However, very few of these studies have analyzed the impact…