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Ion channels are protein structures that facilitate the selective passage of ions across the membrane cells of living organisms. They are known for their high conductance and high selectivity. The precise mechanism between these two…

生物物理 · 物理学 2025-02-12 Mateusz Polakowski , Miłosz Panfil

Potassium channels play critical roles in many physiological processes, providing a selective permeation route for K+ ions in and out of a cell, by employing a carefully designed selectivity filter, evolutionarily conserved from viruses to…

生物物理 · 物理学 2021-04-16 Andrei Mironenko , Ulrich Zachariae , Bert L. de Groot , Wojciech Kopec

Classically allowed transport is shown to compete with quantum tunneling during the ionization of atoms by ultrashort and intense laser pulses, despite Keldysh parameters smaller than unity. This is done by comparing exact probability…

原子物理 · 物理学 2022-01-31 Gabriel M. Lando

We present an equilibrium statistical-mechanical theory of selectivity in biological ion channels. In doing so, we introduce a grand canonical ensemble for ions in a channel's selectivity filter coupled to internal and external bath…

生物物理 · 物理学 2016-05-11 D. G. Luchinsky , W. A. T. Gibby , I. Kaufman , D. A. Timucin , P. V. E. McClintock

Process of quantum tunneling of particles in various physical systems can be effectively controlled even by a weak and slow varying in time electromagnetic signal if to adapt specially its shape to a particular system. During an…

量子物理 · 物理学 2009-02-05 B. I. Ivlev

In this work, we present a quantum transport model for the selectivity filter in the KcsA potassium ion channel. This model is fully consistent with the fact that two conduction pathways are involved in the translocation of ions thorough…

生物物理 · 物理学 2015-06-18 A. A. Cifuentes , F. L. Semião

Recently, it has been suggested that ion channel selectivity filter may exhibit quantum coherence, which may be appropriate to explain ion selection and conduction processes. Potassium channels play a vital role in many physiological…

量子物理 · 物理学 2022-05-31 Mina Seifi , Ali Soltanmanesh , Afshin Shafiee

Ion channels are specific proteins present in the membranes of living cells. They control the flow of specific ions through a cell, initiated by an ion channel's electrochemical gradient. In doing so, they control important physiological…

亚细胞过程 · 定量生物学 2012-09-14 Andrew Das Arulsamy

We study the quantum tunnel effect through a potential barrier employing a semiclassical formulation of quantum mechanics based on expectation values of configuration variables and quantum dispersions as dynamical variables. The evolution…

量子物理 · 物理学 2020-12-30 L. Aragon-Muñoz , G. Chacon-Acosta , H. Hernandez-Hernandez

Specific molecular interactions underlie unexpected and useful phenomena in nanofluidic systems, but require descriptions that go beyond traditional macroscopic hydrodynamics. In this letter, we demonstrate how equilibrium molecular…

介观与纳米尺度物理 · 物理学 2023-06-07 Phillip Helms , Anthony R. Poggioli , David T. Limmer

We investigate relativistic wavepacket dynamics for an electron tunneling through a potential barrier employing space-time resolved solutions to relativistic quantum field theory (QFT) equations. We prove by linking the QFT property of…

量子物理 · 物理学 2026-03-17 M. Alkhateeb , X. Gutierrez de la Cal , M. Pons , D. Sokolovski , A. Matzkin

Recently it was demonstrated that long-lived quantum coherence exists during excitation energy transport in photosynthesis. It is a valid question up to which length, time and mass scales quantum coherence may extend, how to one may detect…

量子物理 · 物理学 2015-05-19 A. Vaziri , M. B. Plenio

The mechanism behind the high throughput rate in K$^{+}$ channels is still an open problem. Recent simulations have shown that the passage of potassium through the K$^{+}$ channel core, the so-called selectivity filter (SF), is water-free…

量子物理 · 物理学 2021-12-15 N. De March , S. D. Prado , L. G. Brunnet

Ion channels are of major interest and form an area of intensive research in the fields of biophysics and medicine since they control many vital physiological functions. The aim of this work is on one hand to propose a fully stochastic and…

生物大分子 · 定量生物学 2016-01-11 Daniela Morale , Mattia Zanella , Vincenzo Capasso , Willi Jaeger

We discuss various models of ion transport through cell membrane channels. Recent experimental data shows that sizes of ion channels are compared to those of ions and that only few ions may be simultaneously in any single channel.…

亚细胞过程 · 定量生物学 2007-06-06 Jan Gomulkiewicz , Jacek Miekisz , Stanislaw Miekisz

We present a methodology based on quantum mechanics for assigning quantum conductivity when an ac field is applied across a variable gap between two plasmonic nanoparticles with an insulator sandwiched between them. The quantum tunneling…

Biological ion channels balance electrostatic and dehydration effects to yield large ion selectivities alongside high transport rates. These macromolecular systems are often interrogated through point mutations of their pore domain,…

介观与纳米尺度物理 · 物理学 2019-07-19 Subin Sahu , Justin Elenewski , Christoph Rohmann , Michael Zwolak

Recent realization of an intense quantum light, namely bright squeezed vacuum, opened a new perspective on quantum light-matter interaction. Several theoretical works have appeared based on coherent state expansions of quantum state of…

量子物理 · 物理学 2025-07-23 Sangwon Kim , Seongjin Ahn , Denis V. Seletskiy , Andrey S. Moskalenko

We study the influence of a tunnel barrier on the quantum transport through a circular cavity. Our analysis in terms of classical trajectories shows that the semiclassical approaches developed for ballistic transport can be adapted to deal…

介观与纳米尺度物理 · 物理学 2009-10-25 Markus Schreier , Klaus Richter , Gert-Ludwig Ingold , Rodolfo A. Jalabert

Assuming that the selectivity filter of KcsA potassium ion channel may exhibit quantum coherence, we extend a previous model by Vaziri and Plenio (2010) to take into account Coulomb repulsion between potassium ions. We show that typical ion…

生物物理 · 物理学 2018-07-04 N. De March , S. D. Prado , L. G. Brunnet
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