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High-resolution microscopy images of tissue specimens provide detailed information about the morphology of normal and diseased tissue. Image analysis of tissue morphology can help cancer researchers develop a better understanding of cancer…

In medical imaging, radiological scans of different modalities serve to enhance different sets of features for clinical diagnosis and treatment planning. This variety enriches the source information that could be used for outcome…

图像与视频处理 · 电气工程与系统科学 2020-06-01 William Le , Francisco Perdigón Romero , Samuel Kadoury

Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilitates nuclei segmentation through two primary methods:…

计算机视觉与模式识别 · 计算机科学 2025-08-22 Xueyuan Li , Can Cui , Ruining Deng , Yucheng Tang , Quan Liu , Tianyuan Yao , Shunxing Bao , Naweed Chowdhury , Haichun Yang , Yuankai Huo

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

图像与视频处理 · 电气工程与系统科学 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Automatic nuclei detection and classification can produce effective information for disease diagnosis. Most existing methods classify nuclei independently or do not make full use of the semantic similarity between nuclei and their grouping…

计算机视觉与模式识别 · 计算机科学 2023-10-24 Junjia Huang , Haofeng Li , Weijun Sun , Xiang Wan , Guanbin Li

Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties in identifying nuclei. Most neural network based methods are…

计算机视觉与模式识别 · 计算机科学 2023-02-23 Wei Lou , Xiang Wan , Guanbin Li , Xiaoying Lou , Chenghang Li , Feng Gao , Haofeng Li

Several machine learning techniques for accurate detection of skin cancer from medical images have been reported. Many of these techniques are based on pre-trained convolutional neural networks (CNNs), which enable training the models based…

计算机视觉与模式识别 · 计算机科学 2021-05-18 Aqsa Saeed Qureshi , Teemu Roos

Over the past few years, silicon photonics-based computing has emerged as a promising alternative to CMOS-based computing for Deep Neural Networks (DNN). Unfortunately, the non-linear operations and the high-precision requirements of DNNs…

Deep learning based methods have achieved the state-of-the-art performance in image denoising. In this paper, a deep learning based denoising method is proposed and a module called fusion block is introduced in the convolutional neural…

图像与视频处理 · 电气工程与系统科学 2021-02-19 Maoyuan Xu , Xiaoping Xie

As deep learning is widely used in the radiology field, the explainability of such models is increasingly becoming essential to gain clinicians' trust when using the models for diagnosis. In this research, three experiment sets were…

图像与视频处理 · 电气工程与系统科学 2022-07-04 Akino Watanabe , Sara Ketabi , Khashayar , Namdar , Farzad Khalvati

Applying deep learning methods to mammography assessment has remained a challenging topic. Dense noise with sparse expressions, mega-pixel raw data resolution, lack of diverse examples have all been factors affecting performance. The lack…

计算机视觉与模式识别 · 计算机科学 2018-07-10 Ulzee An , Khader Shameer , Lakshmi Subramanian

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

图像与视频处理 · 电气工程与系统科学 2025-06-10 Suman Mahapatra , Pradipta Maji

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

计算机视觉与模式识别 · 计算机科学 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Identifying cell types and subtypes in routine histopathology is fundamental for understanding disease. Existing tile-based models capture nuclear detail but miss the broader tissue context that influences cell identity. Current human…

计算机视觉与模式识别 · 计算机科学 2025-11-20 Yinuo Xu , Yan Cui , Mingyao Li , Zhi Huang

Detecting and classifying cells in histopathology H\&E stained whole-slide images is a core task in computational pathology, as it provides valuable insight into the tumor microenvironment. In this work we investigate the impact of ground…

图像与视频处理 · 电气工程与系统科学 2023-12-20 Lydia A. Schoenpflug , Viktor H. Koelzer

Breast cancer is one of the leading causes of death globally, and thus there is an urgent need for early and accurate diagnostic techniques. Although ultrasound imaging is a widely used technique for breast cancer screening, it faces…

图像与视频处理 · 电气工程与系统科学 2025-02-11 Pandiyaraju V , Shravan Venkatraman , Pavan Kumar S , Santhosh Malarvannan , Kannan A

Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral imaging to denoising biomedical sensors. This paper focuses on…

计算工程、金融与科学 · 计算机科学 2016-11-17 Shahin Mohammadi , Neta Zuckerman , Andrea Goldsmith , Ananth Grama

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

计算机视觉与模式识别 · 计算机科学 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

With a large influx of dermoscopy images and a growing shortage of dermatologists, automatic dermoscopic image analysis plays an essential role in skin cancer diagnosis. In this paper, a new deep fully convolutional neural network (FCNN) is…

计算机视觉与模式识别 · 计算机科学 2017-03-17 Jin Qi , Miao Le , Chunming Li , Ping Zhou