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Due to various physical degradation factors and limited counts received, PET image quality needs further improvements. The denoising diffusion probabilistic models (DDPM) are distribution learning-based models, which try to transform a…

图像与视频处理 · 电气工程与系统科学 2022-09-15 Kuang Gong , Keith A. Johnson , Georges El Fakhri , Quanzheng Li , Tinsu Pan

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

Positron Emission Tomography and Magnetic Resonance Imaging (PET-MRI) systems can obtain functional and anatomical scans. PET suffers from a low signal-to-noise ratio. Meanwhile, the k-space data acquisition process in MRI is…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Taofeng Xie , Zhuo-Xu Cui , Chen Luo , Huayu Wang , Congcong Liu , Yuanzhi Zhang , Xuemei Wang , Yanjie Zhu , Guoqing Chen , Dong Liang , Qiyu Jin , Yihang Zhou , Haifeng Wang

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

Diffusion models have shown remarkable flexibility for solving inverse problems without task-specific retraining. However, existing approaches such as Manifold Preserving Guided Diffusion (MPGD) apply only a single gradient update per…

计算机视觉与模式识别 · 计算机科学 2025-06-10 Aditya Chakravarty

Spectral computed tomography (CT) with photon-counting detectors holds immense potential for material discrimination and tissue characterization. However, under ultra-low-dose conditions, the sharply degraded signal-to-noise ratio (SNR) in…

计算机视觉与模式识别 · 计算机科学 2026-02-10 Peng Peng , Xinrui Zhang , Junlin Wang , Lei Li , Shaoyu Wang , Qiegen Liu

Ultra-low-dose CT (ULDCT) imaging can greatly reduce patient radiation exposure, but the resulting scans suffer from severe structured and random noise that degrades image quality. To address this challenge, we propose a novel Plug-and-Play…

图像与视频处理 · 电气工程与系统科学 2026-01-05 Sayantan Dutta , Sudhanya Chatterjee , Ashwini Galande , K. S. Shriram , Bipul Das

Low-dose PET imaging is crucial for reducing patient radiation exposure but faces challenges like noise interference, reduced contrast, and difficulty in preserving physiological details. Existing methods often neglect both…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Mengxiao Geng , Ran Hong , Xiaoling Xu , Bingxuan Li , Qiegen Liu

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

医学物理 · 物理学 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

医学物理 · 物理学 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang

Low-dose Positron Emission Tomography (PET) imaging reduces patient radiation exposure but suffers from increased noise that degrades image quality and diagnostic reliability. Although diffusion models have demonstrated strong denoising…

Deep image prior (DIP) has recently attracted attention owing to its unsupervised positron emission tomography (PET) image reconstruction, which does not require any prior training dataset. In this paper, we present the first attempt to…

医学物理 · 物理学 2023-08-08 Fumio Hashimoto , Yuya Onishi , Kibo Ote , Hideaki Tashima , Taiga Yamaya

Accelerating magnetic resonance imaging (MRI) remains challenging, particularly under realistic acquisition noise. While diffusion models have recently shown promise for reconstructing undersampled MRI data, many approaches lack an explicit…

图像与视频处理 · 电气工程与系统科学 2026-02-06 Nikola Janjušević , Amirhossein Khalilian-Gourtani , Yao Wang , Li Feng

Diffusion models (DM) have achieved remarkable promise in image super-resolution (SR). However, most of them are tailored to solving non-blind inverse problems with fixed known degradation settings, limiting their adaptability to real-world…

计算机视觉与模式识别 · 计算机科学 2024-03-18 Feng Li , Yixuan Wu , Zichao Liang , Runmin Cong , Huihui Bai , Yao Zhao , Meng Wang

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

医学物理 · 物理学 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Objective: Long-axial field-of-view (LAFOV) positron emission tomography (PET) systems allow higher sensitivity, with an increased number of detected lines of response induced by a larger angle of acceptance. However, this extended angle…

Diffusion-based voxel prior modelling is challenging for the reconstruction of large-scale 3D porous microstructures. Due to the demanding requirements for simultaneously modelling both the continuous pore morphology and the discrete…

计算机视觉与模式识别 · 计算机科学 2026-05-06 Yue Shi , Peng Wang , Mingzhe Yu , Yunlong Zhao , Li Liu , Gareth D Hatton , Yan Lyu , Liangxiu Han

Low-dose computed tomography (CT) images suffer from noise and artifacts due to photon starvation and electronic noise. Recently, some works have attempted to use diffusion models to address the over-smoothness and training instability…

图像与视频处理 · 电气工程与系统科学 2024-01-10 Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Hongming Shan

PET is affected by statistical noise due to constraints on tracer dose and scan duration, impacting both diagnostic performance and quantitative accuracy. While deep learning (DL)-based PET denoising methods have been used to improve image…

In PET, the amount of relative (signal-dependent) noise present in different body regions can be significantly different and is inherently related to the number of counts present in that region. The number of counts in a region depends, in…

图像与视频处理 · 电气工程与系统科学 2022-12-20 Ye Li , Jianan Cui , Junyu Chen , Guodong Zeng , Scott Wollenweber , Floris Jansen , Se-In Jang , Kyungsang Kim , Kuang Gong , Quanzheng Li