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The lack of explainability is one of the most prominent disadvantages of deep learning applications in omics. This "black box" problem can undermine the credibility and limit the practical implementation of biomedical deep learning models.…

基因组学 · 定量生物学 2021-08-19 Eloise Withnell , Xiaoyu Zhang , Kai Sun , Yike Guo

Reliable uncertainty quantification (UQ) is essential for deploying large language models (LLMs) in safety-critical scenarios, as it enables them to abstain from responding when uncertain, thereby avoiding hallucinations, i.e., plausible…

计算与语言 · 计算机科学 2026-02-09 Xingtao Zhao , Hao Peng , Dingli Su , Xianghua Zeng , Chunyang Liu , Jinzhi Liao , Philip S. Yu

Term clustering is important in biomedical knowledge graph construction. Using similarities between terms embedding is helpful for term clustering. State-of-the-art term embeddings leverage pretrained language models to encode terms, and…

计算与语言 · 计算机科学 2022-04-04 Sihang Zeng , Zheng Yuan , Sheng Yu

Text has become the predominant form of communication on social media, embedding a wealth of emotional nuances. Consequently, the extraction of emotional information from text is of paramount importance. Despite previous research making…

计算机视觉与模式识别 · 计算机科学 2024-08-16 Bingyu Li , Da Zhang , Zhiyuan Zhao , Junyu Gao , Yuan Yuan

Text embeddings have become an essential part of a variety of language applications. However, methods for interpreting, exploring and reversing embedding spaces are limited, reducing transparency and precluding potentially valuable…

计算与语言 · 计算机科学 2026-01-27 Brian Ondov , Chia-Hsuan Chang , Yujia Zhou , Mauro Giuffrè , Hua Xu

Biomedical question-answering (QA) has gained increased attention for its capability to provide users with high-quality information from a vast scientific literature. Although an increasing number of biomedical QA datasets has been recently…

计算与语言 · 计算机科学 2021-02-17 Gabriele Pergola , Elena Kochkina , Lin Gui , Maria Liakata , Yulan He

Quantum Machine Learning (QML) is considered one of the most promising applications of Quantum Computing in the Noisy Intermediate Scale Quantum (NISQ) era for the impact it is thought to have in the near future. Although promising…

量子物理 · 物理学 2025-08-22 Valeria Repetto , Elia Giuseppe Ceroni , Giuseppe Buonaiuto , Romina D'Aurizio

Natural language processing techniques are being applied to increasingly diverse types of electronic health records, and can benefit from in-depth understanding of the distinguishing characteristics of medical document types. We present a…

计算与语言 · 计算机科学 2019-10-02 Denis Newman-Griffis , Eric Fosler-Lussier

Biomedical text embeddings have primarily been developed using research literature from PubMed, yet clinical cardiology practice relies heavily on procedural knowledge and specialized terminology found in comprehensive textbooks rather than…

计算与语言 · 计算机科学 2025-11-17 Richard J. Young , Alice M. Matthews

Interpretability of machine learning (ML) models becomes more relevant with their increasing adoption. In this work, we address the interpretability of ML based question answering (QA) models on a combination of knowledge bases (KB) and…

计算与语言 · 计算机科学 2019-06-27 Alona Sydorova , Nina Poerner , Benjamin Roth

Objective: Large language models (LLMs) are increasingly applied in biomedical settings, and existing benchmark datasets have played an important role in supporting model development and evaluation. However, these benchmarks often have…

计算与语言 · 计算机科学 2026-01-21 Kriti Bhattarai , Vipina K. Keloth , Donald Wright , Andrew Loza , Yang Ren , Hua Xu

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

计算机视觉与模式识别 · 计算机科学 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

Recent deep learning methods for fMRI-based diagnosis have achieved promising accuracy by modeling functional connectivity networks. However, standard approaches often struggle with noisy interactions, and conventional post-hoc attribution…

机器学习 · 计算机科学 2026-02-25 Kunyu Zhang , Yanwu Yang , Jing Zhang , Xiangjie Shi , Shujian Yu

Learning on small data is a challenge frequently encountered in many real-world applications. In this work we study how effective quantum ensemble models are when trained on small data problems in healthcare and life sciences. We…

Reasoning is key to many decision making processes. It requires consolidating a set of rule-like premises that are often associated with degrees of uncertainty and observations to draw conclusions. In this work, we address both the case…

计算与语言 · 计算机科学 2024-10-15 Timo Pierre Schrader , Lukas Lange , Simon Razniewski , Annemarie Friedrich

Objective: Currently, a major limitation for natural language processing (NLP) analyses in clinical applications is that a concept can be referenced in various forms across different texts. This paper introduces Multi-Ontology Refined…

计算与语言 · 计算机科学 2020-04-15 Steven Jiang , Weiyi Wu , Naofumi Tomita , Craig Ganoe , Saeed Hassanpour

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Competency Questions (CQs) are a cornerstone of requirement elicitation in ontology engineering. CQs represent requirements as a set of natural language questions that an ontology should satisfy; they are traditionally modelled by ontology…

人工智能 · 计算机科学 2026-04-20 Reham Alharbi , Valentina Tamma , Terry R. Payne , Jacopo de Berardinis

Prediction of survival in patients diagnosed with a brain tumour is challenging because of heterogeneous tumour behaviours and responses to treatment. Better estimations of prognosis would support treatment planning and patient support.…

机器学习 · 计算机科学 2021-06-18 Colleen E. Charlton , Michael Tin Chung Poon , Paul M. Brennan , Jacques D. Fleuriot

Recently, the rapid advancements of vision-language models, such as CLIP, leads to significant progress in zero-/few-shot anomaly detection (ZFSAD) tasks. However, most existing CLIP-based ZFSAD methods commonly assume prior knowledge of…

计算机视觉与模式识别 · 计算机科学 2025-06-23 Hong Huang , Weixiang Sun , Zhijian Wu , Jingwen Niu , Donghuan Lu , Xian Wu , Yefeng Zheng