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The rapid digitization of histopathology slides has opened up new possibilities for computational tools in clinical and research workflows. Among these, content-based slide retrieval stands out, enabling pathologists to identify…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Hongyi Wang , Zhengjie Zhu , Jiabo Ma , Fang Wang , Yue Shi , Bo Luo , Jili Wang , Qiuyu Cai , Xiuming Zhang , Yen-Wei Chen , Lanfen Lin , Hao Chen

For doctors to truly trust artificial intelligence, it can't be a black box. They need to understand its reasoning, almost as if they were consulting a colleague. We created HistoLens1 to be that transparent, collaborative partner. It…

人工智能 · 计算机科学 2025-10-29 Sandeep Vissapragada , Vikrant Sahu , Gagan Raj Gupta , Vandita Singh

Whole-slide image visual question answering (WSI-VQA) frames pathology as an extreme-context search problem: to answer a free-form clinical query, a system must first navigate a gigapixel slide under a strict inspection budget to locate…

计算机视觉与模式识别 · 计算机科学 2026-05-25 Chunze Yang , Qidong Liu , Wenjie Zhao , Yue Tang , Jiusong Ge , Di Zhang , Jiashuai Liu , Lei Wu , Junbo Lu , Ni Zhang , Xian Wu , Zeyu Gao , Chen Li

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Diagnosing a whole-slide image is an interactive, multi-stage process of changing magnification and moving between fields. Although recent pathology foundation models demonstrated superior performances, practical agentic systems that decide…

计算机视觉与模式识别 · 计算机科学 2025-10-15 Sheng Wang , Ruiming Wu , Charles Herndon , Yihang Liu , Shunsuke Koga , Jeanne Shen , Zhi Huang

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

计算机视觉与模式识别 · 计算机科学 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Digital pathology involves converting physical tissue slides into high-resolution Whole Slide Images (WSIs), which pathologists analyze for disease-affected tissues. However, large histology slides with numerous microscopic fields pose…

图像与视频处理 · 电气工程与系统科学 2024-02-19 Mobina Mansoori , Sajjad Shahabodini , Jamshid Abouei , Arash Mohammadi , Konstantinos N. Plataniotis

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

图像与视频处理 · 电气工程与系统科学 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

计算机视觉与模式识别 · 计算机科学 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

图像与视频处理 · 电气工程与系统科学 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena

Pathology is experiencing rapid digital transformation driven by whole-slide imaging and artificial intelligence (AI). While deep learning-based computational pathology has achieved notable success, traditional models primarily focus on…

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

图像与视频处理 · 电气工程与系统科学 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

计算机视觉与模式识别 · 计算机科学 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

In pathological research, education, and clinical practice, the decision-making process based on pathological images is critically important. This significance extends to digital pathology image analysis: its adequacy is demonstrated by the…

图像与视频处理 · 电气工程与系统科学 2024-08-19 Zhi-Bo Liu , Xiaobo Pang , Jizhao Wang , Shuai Liu , Chen Li

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Non-invasive brain imaging techniques allow understanding the behavior and macro changes in the brain to determine the progress of a disease. However, computational pathology provides a deeper understanding of brain disorders at cellular…

图像与视频处理 · 电气工程与系统科学 2023-01-18 Gabriel Jimenez , Daniel Racoceanu

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

计算机视觉与模式识别 · 计算机科学 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu
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