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Deep learning offers transformative potential in medical imaging, yet its clinical adoption is frequently hampered by challenges such as data scarcity, distribution shifts, and the need for robust task generalization. Prompt-based…

图像与视频处理 · 电气工程与系统科学 2025-07-03 Hao Yang , Xinlong Liang , Zhang Li , Yue Sun , Zheyu Hu , Xinghe Xie , Behdad Dashtbozorg , Jincheng Huang , Shiwei Zhu , Luyi Han , Jiong Zhang , Shanshan Wang , Ritse Mann , Qifeng Yu , Tao Tan

We propose Context-Adaptive Multi-Prompt Embedding, a novel approach to enrich semantic representations in vision-language contrastive learning. Unlike standard CLIP-style models that rely on a single text embedding, our method introduces…

机器学习 · 计算机科学 2025-08-07 Dahun Kim , Anelia Angelova

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

统计方法学 · 统计学 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

The analysis of FFPE tissue sections stained with haematoxylin and eosin (H&E) or immunohistochemistry (IHC) is an essential part of the pathologic assessment of surgically resected breast cancer specimens. IHC staining has been broadly…

Proteomics data is essential to pathogenic understanding of a disease phenotype. In cancer, analysis of molecular signatures enables precision medicine through the identification of biological processes that drive individualized tumor…

定量方法 · 定量生物学 2025-09-30 Irsyad Adam , Zekai Chen , David Laub , Shaun Porwal , Arda Pekis , Kevin Brown

The recent introduction of prompt tuning based on pre-trained vision-language models has dramatically improved the performance of multi-label image classification. However, some existing strategies that have been explored still have…

计算机视觉与模式识别 · 计算机科学 2024-05-14 Xiangyu Wu , Qing-Yuan Jiang , Yang Yang , Yi-Feng Wu , Qing-Guo Chen , Jianfeng Lu

Pre-trained protein models (PTPMs) represent a protein with one fixed embedding and thus are not capable for diverse tasks. For example, protein structures can shift, namely protein folding, between several conformations in various…

人工智能 · 计算机科学 2022-02-08 Qiang Zhang , Zeyuan Wang , Yuqiang Han , Haoran Yu , Xurui Jin , Huajun Chen

While Multimodal Large Language Models (MLLMs) have experienced significant advancement in visual understanding and reasoning, their potential to serve as powerful, flexible, interpretable, and text-driven models for Image Quality…

计算机视觉与模式识别 · 计算机科学 2024-07-12 Tianhe Wu , Kede Ma , Jie Liang , Yujiu Yang , Lei Zhang

Chemical reasoning inherently integrates visual, textual, and symbolic modalities, yet existing benchmarks rarely capture this complexity, often relying on simple image-text pairs with limited chemical semantics. As a result, the actual…

人工智能 · 计算机科学 2025-11-25 Zhiyuan Huang , Baichuan Yang , Zikun He , Yanhong Wu , Fang Hongyu , Zhenhe Liu , Lin Dongsheng , Bing Su

Accurate analysis of pathological images is essential for automated tumor diagnosis but remains challenging due to high structural similarity and subtle morphological variations in tissue images. Current vision-language (VL) models often…

计算机视觉与模式识别 · 计算机科学 2025-10-01 Yating Huang , Ziyan Huang , Lintao Xiang , Qijun Yang , Hujun Yin

The quantification of biomarkers on immunohistochemistry breast cancer images is essential for defining appropriate therapy for breast cancer patients, as well as for extracting relevant information on disease prognosis. This is an arduous…

图像与视频处理 · 电气工程与系统科学 2023-11-27 Blanca Maria Priego-Torresa , Barbara Lobato-Delgado , Lidia Atienza-Cuevas , Daniel Sanchez-Morillo

Despite the success of Large Vision--Language Models (LVLMs), most existing architectures suffer from a representation bottleneck: they rely on static, instruction-agnostic vision encoders whose visual representations are utilized in an…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Hanpeng Liu , Yaqian Li , Zidan Wang , Shuoxi Zhang , Zihao Bo , Rinyoichi Takezoe , Kaiwen Long , Kun He

Registration of serial whole-slide histopathological images (WSIs) is critical for enabling direct comparison across diverse stains and for preparing paired datasets in artificial intelligence (AI) workflows such as virtual staining and…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Zeyu Liu , Shengwei Ding

The goal of interactive image segmentation is to delineate specific regions within an image via visual or language prompts. Low-latency and high-quality interactive segmentation with diverse prompts remain challenging for existing…

计算机视觉与模式识别 · 计算机科学 2024-04-02 Qin Liu , Jaemin Cho , Mohit Bansal , Marc Niethammer

In this paper, we present the Draw-and-Understand framework, exploring how to integrate visual prompting understanding capabilities into Multimodal Large Language Models (MLLMs). Visual prompts allow users to interact through multi-modal…

计算机视觉与模式识别 · 计算机科学 2025-02-25 Weifeng Lin , Xinyu Wei , Ruichuan An , Peng Gao , Bocheng Zou , Yulin Luo , Siyuan Huang , Shanghang Zhang , Hongsheng Li

While multiplex immunofluorescence (mIF) imaging provides deep, spatially-resolved molecular data, integrating this information with the morphological standard of Hematoxylin & Eosin (H&E) can be very important for obtaining complementary…

定量方法 · 定量生物学 2025-08-08 Jillur Rahman Saurav , Mohammad Sadegh Nasr , Jacob M. Luber

Going beyond mere fine-tuning of vision-language models (VLMs), learnable prompt tuning has emerged as a promising, resource-efficient alternative. Despite their potential, effectively learning prompts faces the following challenges: (i)…

计算机视觉与模式识别 · 计算机科学 2024-06-21 Hari Chandana Kuchibhotla , Sai Srinivas Kancheti , Abbavaram Gowtham Reddy , Vineeth N Balasubramanian

Pre-trained large vision-language models (VLMs) like CLIP have revolutionized visual representation learning using natural language as supervisions, and demonstrated promising generalization ability. In this work, we propose ViP, a novel…

计算机视觉与模式识别 · 计算机科学 2024-09-04 Xiao Fang , Yi Lin , Dong Zhang , Kwang-Ting Cheng , Hao Chen

With the rapid development of computational pathology, many AI-assisted diagnostic tasks have emerged. Cellular nuclei segmentation can segment various types of cells for downstream analysis, but it relies on predefined categories and lacks…

计算机视觉与模式识别 · 计算机科学 2025-03-03 Chunlin Zhong , Shuang Hao , Junhua Wu , Xiaona Chang , Jiwei Jiang , Xiu Nie , He Tang , Xiang Bai

Iconicity, the resemblance between linguistic form and meaning, is pervasive in signed languages, offering a natural testbed for visual grounding. For vision-language models (VLMs), the challenge is to recover such essential mappings from…

计算机视觉与模式识别 · 计算机科学 2026-05-21 Onur Keleş , Aslı Özyürek , Gerardo Ortega , Kadir Gökgöz , Esam Ghaleb