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相关论文: Decomposing Physician Disagreement in HealthBench

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Medical image segmentation annotation suffers from inter-rater variability (IRV) due to differences in annotators' expertise and the inherent blurriness of medical images. Standard approaches that simply average expert labels are flawed, as…

计算机视觉与模式识别 · 计算机科学 2025-10-14 Chen Zhong , Yuxuan Yang , Xinyue Zhang , Ruohan Ma , Yong Guo , Gang Li , Jupeng Li

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

Large language models have demonstrated remarkable performance in a wide range of medical benchmarks. Yet underneath the seemingly promising results lie salient growth areas, especially in cutting-edge frontiers such as multimodal…

Intra-physician prescribing variability, the probability that one physician issues discordant decisions for two patients deemed comparable on observed covariates, holds great impact in quality of care, safety and cost. However, there are no…

Medical artificial intelligence (AI) systems, particularly multimodal vision-language models (VLM), often exhibit intersectional biases where models are systematically less confident in diagnosing marginalised patient subgroups. Such bias…

计算机视觉与模式识别 · 计算机科学 2025-12-25 Yupeng Zhang , Adam G. Dunn , Usman Naseem , Jinman Kim

The evaluation and improvement of medical large language models (LLMs) are critical for their real-world deployment, particularly in ensuring accuracy, safety, and ethical alignment. Existing frameworks inadequately dissect domain-specific…

计算与语言 · 计算机科学 2025-03-11 Luyi Jiang , Jiayuan Chen , Lu Lu , Xinwei Peng , Lihao Liu , Junjun He , Jie Xu

Deep neural networks are known to be data-driven and label noise can have a marked impact on model performance. Recent studies have shown great robustness to classic image recognition even under a high noisy rate. In medical applications,…

计算机视觉与模式识别 · 计算机科学 2021-03-23 Lie Ju , Xin Wang , Lin Wang , Dwarikanath Mahapatra , Xin Zhao , Mehrtash Harandi , Tom Drummond , Tongliang Liu , Zongyuan Ge

Medical large language model (LLM) evaluations rely on simplified, exam-style benchmarks that rarely reflect the ambiguity of real-world medical inquiries. We introduce the CLinical Evaluation of Ambiguity and Reliability (CLEAR) framework,…

计算与语言 · 计算机科学 2026-05-12 Kevin H. Guo , Chao Yan , Avinash Baidya , Katherine Brown , Xiang Gao , Juming Xiong , Zhijun Yin , Bradley A. Malin

Patient-clinician communication is an asymmetric-information problem: patients often do not disclose fears, misconceptions, or practical barriers unless clinicians elicit them skillfully. Effective medical dialogue therefore requires…

计算与语言 · 计算机科学 2026-04-13 Yikun Han , Joey Chan , Jingyuan Chen , Mengting Ai , Simo Du , Yue Guo

Biomedical retrieval-augmented large language models (LLMs) often face evidence that is incomplete, misleading, or internally contradictory, yet evaluation usually emphasizes answer accuracy under helpful context rather than reliability…

计算与语言 · 计算机科学 2026-05-15 Yikun Han , Mengfei Lan , Halil Kilicoglu

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

定量方法 · 定量生物学 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

Medical AI algorithms can often experience degraded performance when evaluated on previously unseen sites. Addressing cross-site performance disparities is key to ensuring that AI is equitable and effective when deployed on diverse patient…

机器学习 · 计算机科学 2021-11-17 Eric Wu , Kevin Wu , James Zou

Miscalibrated confidence scores are a practical obstacle to deploying AI in clinical settings. A model that is always overconfident offers no useful signal for deferral. We present a multi-agent framework that combines domain-specific…

人工智能 · 计算机科学 2026-03-26 John Ray B. Martinez

Medical imaging is spearheading the AI transformation of healthcare. Performance reporting is key to determine which methods should be translated into clinical practice. Frequently, broad conclusions are simply derived from mean performance…

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

计算机视觉与模式识别 · 计算机科学 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

We propose an evaluation framework for class probability estimates (CPEs) in the presence of label uncertainty, which is commonly observed as diagnosis disagreement between experts in the medical domain. We also formalize evaluation metrics…

机器学习 · 统计学 2021-03-23 Takahiro Mimori , Keiko Sasada , Hirotaka Matsui , Issei Sato

Segmentation is the identification of anatomical regions of interest, such as organs, tissue, and lesions, serving as a fundamental task in computer-aided diagnosis in medical imaging. Although deep learning models have achieved remarkable…

图像与视频处理 · 电气工程与系统科学 2025-12-09 Tianyi Ren , Daniel Low , Pittra Jaengprajak , Juampablo Heras Rivera , Jacob Ruzevick , Mehmet Kurt

Current evaluations of medical consultation agents often prioritize outcome-oriented tasks, frequently overlooking the end-to-end process integrity and clinical safety essential for real-world practice. While recent interactive benchmarks…

人工智能 · 计算机科学 2026-01-21 Chuhan Qiao , Jianghua Huang , Daxing Zhao , Ziding Liu , Yanjun Shen , Bing Cheng , Wei Lin , Kai Wu

Algorithmic bias in medical imaging can perpetuate health disparities, yet its causes remain poorly understood in segmentation tasks. While fairness has been extensively studied in classification, segmentation remains underexplored despite…

图像与视频处理 · 电气工程与系统科学 2025-11-04 Aditya Parikh , Sneha Das , Aasa Feragen

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

图像与视频处理 · 电气工程与系统科学 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li