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Age is one of the major known risk factors for Alzheimer's Disease (AD). Detecting AD early is crucial for effective treatment and preventing irreversible brain damage. Brain age, a measure derived from brain imaging reflecting structural…

图像与视频处理 · 电气工程与系统科学 2024-05-07 Jay Shah , Md Mahfuzur Rahman Siddiquee , Yi Su , Teresa Wu , Baoxin Li

Pre-trained diffusion models have shown great potential in real-world image super-resolution (Real-ISR) tasks by enabling high-resolution reconstructions. While one-step diffusion (OSD) methods significantly improve efficiency compared to…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Zongliang Wu , Siming Zheng , Peng-Tao Jiang , Xin Yuan

We present Direct Reward Fine-Tuning (DRaFT), a simple and effective method for fine-tuning diffusion models to maximize differentiable reward functions, such as scores from human preference models. We first show that it is possible to…

计算机视觉与模式识别 · 计算机科学 2024-06-24 Kevin Clark , Paul Vicol , Kevin Swersky , David J Fleet

Diabetic Retinopathy (DR) is a leading cause of vision loss worldwide, requiring early detection to preserve sight. Limited access to physicians often leaves DR undiagnosed. To address this, AI models utilize lesion segmentation for…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Shivum Telang

Guidance serves as a key concept in diffusion models, yet its effectiveness is often limited by the need for extra data annotation or classifier pretraining. That is why guidance was harnessed from self-supervised learning backbones, like…

计算机视觉与模式识别 · 计算机科学 2023-12-15 Vincent Tao Hu , Yunlu Chen , Mathilde Caron , Yuki M. Asano , Cees G. M. Snoek , Bjorn Ommer

Longitudinal imaging is able to capture both static anatomical structures and dynamic changes in disease progression towards earlier and better patient-specific pathology management. However, conventional approaches for detecting diabetic…

This paper studies Distributionally Robust Optimization (DRO), a fundamental framework for enhancing the robustness and generalization of statistical learning and optimization. An effective ambiguity set for DRO must involve distributions…

机器学习 · 计算机科学 2025-10-28 Jiaqi Wen , Jianyi Yang

While likelihood-based generative models, particularly diffusion and autoregressive models, have achieved remarkable fidelity in visual generation, the maximum likelihood estimation (MLE) objective, which minimizes the forward KL…

计算机视觉与模式识别 · 计算机科学 2025-06-24 Kaiwen Zheng , Yongxin Chen , Huayu Chen , Guande He , Ming-Yu Liu , Jun Zhu , Qinsheng Zhang

Text-to-image diffusion models deliver high-quality images, yet aligning them with human preferences remains challenging. We revisit diffusion-based Direct Preference Optimization (DPO) for these models and identify a critical pathology:…

计算机视觉与模式识别 · 计算机科学 2025-12-03 Minghao Fu , Guo-Hua Wang , Tianyu Cui , Qing-Guo Chen , Zhao Xu , Weihua Luo , Kaifu Zhang

Dynamic treatment regimens (DTRs) aim at tailoring individualized sequential treatment rules that maximize cumulative beneficial outcomes by accommodating patients' heterogeneity in decision-making. For many chronic diseases including type…

统计方法学 · 统计学 2024-04-23 Mochuan Liu , Yuanjia Wang , Haoda Fu , Donglin Zeng

Efficiently aligning large-scale video diffusion models with human intent requires a scalable and trajectory-aware pathway that bridges the inherent discrepancy between training noise distributions and practical inference trajectories.…

计算机视觉与模式识别 · 计算机科学 2026-05-11 Jingyuan Zhu , Biaolong Chen , Le Zhang , Aixi Zhang , Hao Jiang , Pipei Huang

Ordinal regression refers to classifying object instances into ordinal categories. Ordinal regression is crucial for applications in various areas like facial age estimation, image aesthetics assessment, and even cancer staging, due to its…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Jinhong Wang , Jintai Chen , Jian Liu , Dongqi Tang , Danny Z. Chen , Jian Wu

Diabetic Retinopathy (DR) is among the worlds leading vision loss causes in diabetic patients. DR is a microvascular disease that affects the eye retina, which causes vessel blockage and therefore cuts the main source of nutrition for the…

图像与视频处理 · 电气工程与系统科学 2021-06-24 Israa Odeh , Mouhammd Alkasassbeh , Mohammad Alauthman

Diabetic Retinopathy (DR) is a significant cause of blindness globally, highlighting the urgent need for early detection and effective treatment. Recent advancements in Machine Learning (ML) techniques have shown promise in DR detection,…

计算机视觉与模式识别 · 计算机科学 2023-09-06 D. Dhinakaran , L. Srinivasan , D. Selvaraj , S. M. Udhaya Sankar

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, necessitating early detection to prevent vision loss. Current automated DR detection systems often struggle with poor-quality images, lack interpretability, and…

图像与视频处理 · 电气工程与系统科学 2025-09-03 Idowu Paul Okuwobi , Jingyuan Liu , Jifeng Wan , Jiaojiao Jiang

Reinforcement learning has emerged as a powerful tool for improving diffusion-based text-to-image models, but existing methods are largely limited to single-task optimization. Extending RL to multiple tasks is challenging: joint…

机器学习 · 计算机科学 2026-05-15 Quanhao Li , Junqiu Yu , Kaixun Jiang , Yujie Wei , Zhen Xing , Pandeng Li , Ruihang Chu , Shiwei Zhang , Yu Liu , Zuxuan Wu

Diabetic Retinopathy (DR) is a complication of long-standing, unchecked diabetes and one of the leading causes of blindness in the world. This paper focuses on improved and robust methods to extract some of the features of DR, viz. Blood…

图像与视频处理 · 电气工程与系统科学 2022-07-12 Soham Basu , Sayantan Mukherjee , Ankit Bhattacharya , Anindya Sen

Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical images, particularly fundus images, remains costly and…

计算机视觉与模式识别 · 计算机科学 2025-12-16 Xi Luo , Shixin Xu , Ying Xie , JianZhong Hu , Yuwei He , Yuhui Deng , Huaxiong Huang

The covariate shift is a challenging problem in supervised learning that results from the discrepancy between the training and test distributions. An effective approach which recently drew a considerable attention in the research community…

机器学习 · 计算机科学 2013-11-27 Yun-Qian Miao , Ahmed K. Farahat , Mohamed S. Kamel

Distribution Matching Distillation (DMD) facilitates efficient inference by distilling multi-step diffusion models into few-step variants. Concurrently, Reinforcement Learning (RL) has emerged as a vital tool for aligning generative models…