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Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

人工智能 · 计算机科学 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

We introduce PRISM (Predictive Reasoning in Sequential Medicine), a transformer-based architecture designed to model the sequential progression of clinical decision-making processes. Unlike traditional approaches that rely on isolated…

计算与语言 · 计算机科学 2025-06-16 Lionel Levine , John Santerre , Alex S. Young , T. Barry Levine , Francis Campion , Majid Sarrafzadeh

Reasoning capabilities are crucial for reliable medical visual question answering (VQA); however, existing datasets rarely include reasoning explanations. We address this by generating reasoning trajectories for six medical VQA benchmarks…

机器学习 · 计算机科学 2026-05-07 Halil Ibrahim Gulluk , Olivier Gevaert

Traffic signal control is a critical task in intelligent transportation systems, yet conventional fixed-time and rule-based methods often struggle to adapt to dynamic traffic demand and provide limited decision interpretability. This study…

人工智能 · 计算机科学 2026-04-28 Jiazhao Shi

Trustworthy survival prediction is essential for clinical decision making. Longitudinal electronic health records (EHRs) provide a uniquely powerful opportunity for the prediction. However, it is challenging to accurately model the…

机器学习 · 计算机科学 2025-08-04 Sihang Zeng , Lucas Jing Liu , Jun Wen , Meliha Yetisgen , Ruth Etzioni , Gang Luo

Answering complex medical questions requires not only domain expertise and patient-specific information, but also structured and multi-perspective reasoning. Existing multi-agent approaches often rely on fixed roles or shallow interaction…

人工智能 · 计算机科学 2026-03-04 Siqi Ma , Jiajie Huang , Fan Zhang , Yue Shen , Jinlin Wu , Guohui Fan , Zhu Zhang , Zelin Zang

Personalized healthcare decisions require reasoning about how physiological and behavioral variables influence an individual patient over time. Existing temporal causal discovery methods are poorly matched to this setting: cohort-level…

机器学习 · 计算机科学 2026-05-11 Elahe Khatibi , Ziyu Wang , Saba A. Farahani , Di Huang , Hung Cao , Ramesh Jain , Amir M. Rahmani

The increasing capture and analysis of large-scale longitudinal health data offer opportunities to improve healthcare and advance medical understanding. However, a critical gap exists between (a) -- the observation of patterns and…

人机交互 · 计算机科学 2025-08-26 Arran Zeyu Wang , David Borland , David Gotz

Large language model (LLM) agents deployed in clinical settings often exhibit abrupt, threshold-driven behavior, offering little visibility into accumulating risk prior to escalation. In real-world care, however, clinicians act on gradually…

人工智能 · 计算机科学 2026-05-01 Sukesh Subaharan , Venkatesan VS , Murugadasan P , Sivakumar D , Gautham N , Ganeshkumar M

Objective Structured Clinical Examinations (OSCEs) are essential for medical training, but they require significant resources, including professional actors and expert medical feedback. Although Large Language Models (LLMs) have introduced…

人机交互 · 计算机科学 2025-08-20 Henrik Voigt , Yurina Sugamiya , Kai Lawonn , Sina Zarrieß , Atsuo Takanishi

Wearables and mobile health applications are increasingly adopted for self-management of chronic illnesses; yet the data feels overwhelming for older adults with cardiovascular disease (CVD). This study explores how they make sense of…

Effective clinical decision-making depends on iterative, multimodal reasoning across diverse sources of evidence. The recent emergence of multimodal reasoning models has significantly transformed the landscape of solving complex tasks.…

计算与语言 · 计算机科学 2025-11-04 Zhongzhen Huang , Linjie Mu , Yakun Zhu , Xiangyu Zhao , Shaoting Zhang , Xiaofan Zhang

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Clinical text provides essential information to estimate the acuity of a patient during hospital stays in addition to structured clinical data. In this study, we explore how clinical text can complement a clinical predictive learning task.…

Signal Temporal Logic (STL) is a formal language over continuous-time signals (such as trajectories of a multi-agent system) that allows for the specification of complex spatial and temporal system requirements (such as staying sufficiently…

机器人学 · 计算机科学 2023-10-17 Joris Verhagen , Lars Lindemann , Jana Tumova

Medical vision--language models (VLMs) have shown strong potential for medical visual question answering (VQA), yet their reasoning remains largely text-centric: images are encoded once as static context, and subsequent inference is…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Suyang Xi , Songtao Hu , Yuxiang Lai , Wangyun Dan , Yaqi Liu , Shansong Wang , Xiaofeng Yang

There are two main barriers to using large language models (LLMs) in clinical reasoning. Firstly, while LLMs exhibit significant promise in Natural Language Processing (NLP) tasks, their performance in complex reasoning and planning falls…

人工智能 · 计算机科学 2024-12-31 Shengxin Hong , Liang Xiao , Xin Zhang , Jianxia Chen

Large language models (LLMs), particularly those with reasoning capabilities, have rapidly advanced in recent years, demonstrating significant potential across a wide range of applications. However, their deployment in healthcare,…

人工智能 · 计算机科学 2025-02-27 Guoxin Wang , Minyu Gao , Shuai Yang , Ya Zhang , Lizhi He , Liang Huang , Hanlin Xiao , Yexuan Zhang , Wanyue Li , Lu Chen , Jintao Fei , Xin Li

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

计算与语言 · 计算机科学 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Large language models (LLMs) face significant challenges in specialized biomedical tasks due to the inherent complexity of medical reasoning and the sensitive nature of clinical data. Existing LLMs often struggle with intricate medical…

计算与语言 · 计算机科学 2026-05-12 Zongxian Yang , Jiayu Qian , Kay Chen Tan , Hau-San Wong , Yulong Chen , Haoyu Zhang , Zhi-An Huang