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Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…

图像与视频处理 · 电气工程与系统科学 2024-12-10 Mozhgan Naderi , Maryam Rastgarpour , Amir Reza Takhsha

Parkinson's disease (PD) is a chronic and complex neurodegenerative disorder influenced by genetic, clinical, and lifestyle factors. Predicting this disease early is challenging because it depends on traditional diagnostic methods that face…

One of the symptoms observed in the early stages of Parkinson's Disease (PD) is speech impairment. Speech disorders can be used to detect this disease before it degenerates. This work analyzes speech features and machine learning approaches…

音频与语音处理 · 电气工程与系统科学 2021-11-22 Adedolapo Aishat Toye , Suryaprakash Kompalli

Parkinson's disease (PD) is a progressive neurological disorder that impairs movement control, leading to symptoms such as tremors, stiffness, and bradykinesia. Many researchers analyzing handwriting data for PD detection typically rely on…

信号处理 · 电气工程与系统科学 2024-12-25 Jungpil Shin , Abu Saleh Musa Miah , Koki Hirooka , Md. Al Mehedi Hasan , Md. Maniruzzaman

With widespread adoption of electronic health records, there is an increased emphasis for predictive models that can effectively deal with clinical time-series data. Powered by Recurrent Neural Network (RNN) architectures with Long…

机器学习 · 统计学 2018-07-17 Huan Song , Deepta Rajan , Jayaraman J. Thiagarajan , Andreas Spanias

Efficient early diagnosis is paramount in addressing the complexities of Parkinson's disease because timely intervention can substantially mitigate symptom progression and improve patient outcomes. In this paper, we present a pioneering…

信号处理 · 电气工程与系统科学 2024-04-25 Alireza Rashnu , Armin Salimi-Badr

Background: Parkinson's disease remains a major neurodegenerative disorder with high misdiagnosis rates, primarily due to reliance on clinical rating scales. Recent studies have demonstrated a strong association between gut microbiota and…

人工智能 · 计算机科学 2025-09-10 Bo Yu , Zhixiu Hua , Bo Zhao

FDG-PET reveals altered brain metabolism in individuals with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Some biomarkers derived from FDG-PET by computer-aided-diagnosis (CAD) technologies have been proved that they can…

图像与视频处理 · 电气工程与系统科学 2021-11-10 Wenju Cui , Caiying Yan , Zhuangzhi Yan , Yunsong Peng , Yilin Leng , Chenlu Liu , Shuangqing Chen , Xi Jiang

Accurate early diagnosis and monitoring of neurodegenerative conditions is essential for effective disease management and delivery of medication and treatment. This research develops automatic methods for detecting brain imaging preclinical…

神经与进化计算 · 计算机科学 2019-10-15 Amir Dehsarvi , Stephen L. Smith

Parkinson's disease (PD), a neurodegenerative disorder, often manifests as speech and voice dysfunction. While utilizing voice data for PD detection has great potential in clinical applications, the widely used deep learning models…

机器学习 · 计算机科学 2023-09-26 Yicheng Wang , Xiaotian Han , Leisheng Yu , Na Zou

A great deal of effort has been devoted to discovering a particular genetic disorder, but its classification across a broad spectrum of disorder classes and types remains elusive. Early diagnosis of genetic disorders enables timely…

人工智能 · 计算机科学 2024-12-04 Abu Bakar Siddik , Faisal R. Badal , Afroza Islam

At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

机器学习 · 计算机科学 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

Speech-based Parkinson's disease (PD) detection has gained attention for its automated, cost-effective, and non-intrusive nature. As research studies usually rely on data from diagnostic-oriented speech tasks, this work explores the…

音频与语音处理 · 电气工程与系统科学 2025-08-29 Terry Yi Zhong , Esther Janse , Cristian Tejedor-Garcia , Louis ten Bosch , Martha Larson

Parkinsons disease, the fastest growing neurodegenerative disorder globally, has seen a 50 percent increase in cases within just two years. As speech, memory, and motor symptoms worsen over time, early diagnosis is crucial for preserving…

定量方法 · 定量生物学 2024-12-02 Diya Vatsavai , Anya Iyer , Ashwin A. Nair

This work aims to tackle the Parkinson's disease (PD) detection problem from the speech signal in a bilingual setting by proposing an ad-hoc dual-head deep neural architecture for type-based binary classification. One head is specialized…

音频与语音处理 · 电气工程与系统科学 2025-11-13 Moreno La Quatra , Juan Rafael Orozco-Arroyave , Marco Sabato Siniscalchi

The research explores the utilization of a deep learning model employing an attention mechanism in medical text mining. It targets the challenge of analyzing unstructured text information within medical data. This research seeks to enhance…

计算与语言 · 计算机科学 2024-06-04 Lingxi Xiao , Muqing Li , Yinqiu Feng , Meiqi Wang , Ziyi Zhu , Zexi Chen

Attention-based deep networks have been successfully applied on textual data in the field of NLP. However, their application on protein sequences poses additional challenges due to the weak semantics of the protein words, unlike the plain…

机器学习 · 计算机科学 2022-08-29 Ashish Ranjan , Md Shah Fahad , Akshay Deepak

We present a framework to recognize Parkinson's disease (PD) through an English pangram utterance speech collected using a web application from diverse recording settings and environments, including participants' homes. Our dataset includes…

In this work, the issue of Parkinson's disease (PD) diagnostics using non-invasive antemortem techniques was tackled. A deep learning approach for classification of raw speech recordings in patients with diagnosed PD was proposed. The core…

计算与语言 · 计算机科学 2022-04-28 Maurycy Chronowski , Maciej Klaczynski , Malgorzata Dec-Cwiek , Karolina Porebska

Incorporating human domain knowledge for breast tumor diagnosis is challenging, since shape, boundary, curvature, intensity, or other common medical priors vary significantly across patients and cannot be employed. This work proposes a new…

图像与视频处理 · 电气工程与系统科学 2020-09-03 Aleksandar Vakanski , Min Xian , Phoebe Freer