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Bridging clinical diagnostic reasoning with AI remains a central challenge in medical imaging. We introduce MedCLM, an automated pipeline that converts detection datasets into large-scale medical visual question answering (VQA) data with…

计算机视觉与模式识别 · 计算机科学 2025-10-07 Soo Yong Kim , Suin Cho , Vincent-Daniel Yun , Gyeongyeon Hwang

As Vision-Language Models (VLMs) increasingly gain traction in medical applications, clinicians are progressively expecting AI systems not only to generate textual diagnoses but also to produce corresponding medical images that integrate…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Junjie Yang , Yuhao Yan , Gang Wu , Yuxuan Wang , Ruoyu Liang , Xinjie Jiang , Xiang Wan , Fenglei Fan , Yongquan Zhang , Feiwei Qin , Changmiao Wang

Automated clinical diagnosis remains a core challenge in medical AI, which usually requires models to integrate multi-modal data and reason across complex, case-specific contexts. Although recent methods have advanced medical report…

计算与语言 · 计算机科学 2026-01-21 Yuezhe Yang , Hao Wang , Yige Peng , Jinman Kim , Lei Bi

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

人工智能 · 计算机科学 2025-01-27 Arjun R. Malghan

High-performing medical Large Language Models (LLMs) typically require extensive fine-tuning with substantial computational resources, limiting accessibility for resource-constrained healthcare institutions. This study introduces a…

计算与语言 · 计算机科学 2025-10-17 Ziad Elshaer , Essam A. Rashed

Recent advances in large language models (LLMs) have demonstrated impressive reasoning capacities that mirror human-like thinking. However, whether LLMs possess genuine fluid intelligence (i.e., the ability to reason abstractly and…

Medical diagnostics is a high-stakes and complex domain that is critical to patient care. However, current evaluations of large language models (LLMs) remain limited in capturing key challenges of clinical diagnostic scenarios. Most rely on…

计算与语言 · 计算机科学 2026-04-21 Xiangxu Zhang , Lei Li , Yanyun Zhou , Xiao Zhou , Yingying Zhang , Xian Wu

The remarkable progress of Multi-modal Large Language Models (MLLMs) has garnered unparalleled attention, due to their superior performance in visual contexts. However, their capabilities in visual math problem-solving remain insufficiently…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Renrui Zhang , Dongzhi Jiang , Yichi Zhang , Haokun Lin , Ziyu Guo , Pengshuo Qiu , Aojun Zhou , Pan Lu , Kai-Wei Chang , Peng Gao , Hongsheng Li

Despite rapid progress in large-scale language and vision models, AI agents still suffer from a fundamental limitation: they cannot remember. Without reliable memory, agents catastrophically forget past experiences, struggle with…

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

机器学习 · 计算机科学 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

计算与语言 · 计算机科学 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

机器学习 · 计算机科学 2024-08-26 Zhihao Yu , Yujie Jin , Yongxin Xu , Xu Chu , Yasha Wang , Junfeng Zhao

Large language models (LLMs), despite their remarkable progress across various general domains, encounter significant barriers in medicine and healthcare. This field faces unique challenges such as domain-specific terminologies and…

计算与语言 · 计算机科学 2024-06-06 Xiangru Tang , Anni Zou , Zhuosheng Zhang , Ziming Li , Yilun Zhao , Xingyao Zhang , Arman Cohan , Mark Gerstein

Medical Question-Answering (QA) encompasses a broad spectrum of tasks, including multiple choice questions (MCQ), open-ended text generation, and complex computational reasoning. Despite this variety, a unified framework for delivering…

计算与语言 · 计算机科学 2025-06-23 Xiaotian Zhang , Yuan Wang , Zhaopeng Feng , Ruizhe Chen , Zhijie Zhou , Yan Zhang , Hongxia Xu , Jian Wu , Zuozhu Liu

While Multimodal Large Language Models (MLLMs) show promising performance in automated electrocardiogram interpretation, it remains unclear whether they genuinely perform actual step-by-step reasoning or just rely on superficial visual…

机器学习 · 计算机科学 2026-03-17 Jungwoo Oh , Hyunseung Chung , Junhee Lee , Min-Gyu Kim , Hangyul Yoon , Ki Seong Lee , Youngchae Lee , Muhan Yeo , Edward Choi

As large language models (LLMs) enter the medical domain, most benchmarks evaluate them on question answering or descriptive reasoning, overlooking quantitative reasoning critical to clinical decision-making. Existing datasets like…

计算与语言 · 计算机科学 2025-11-03 Kangkun Mao , Jinru Ding , Jiayuan Chen , Mouxiao Bian , Ruiyao Chen , Xinwei Peng , Sijie Ren , Linyang Li , Jie Xu

Large Reasoning Models (LRMs) have introduced a new paradigm in AI by enabling models to ``think before responding" via chain-of-thought reasoning. However, the absence of open and reproducible recipes for building reasoning-centric medical…

计算机视觉与模式识别 · 计算机科学 2026-02-19 Xiaoke Huang , Juncheng Wu , Hui Liu , Xianfeng Tang , Yuyin Zhou

Recent advances in reasoning with large language models (LLMs)has shown remarkable reasoning capabilities in domains such as mathematics and coding, yet their application to clinical diagnosis remains underexplored. Here, we introduce…

计算与语言 · 计算机科学 2025-04-16 Wuyang Lan , Wenzheng Wang , Changwei Ji , Guoxing Yang , Yongbo Zhang , Xiaohong Liu , Song Wu , Guangyu Wang

Despite significant progress, large language models (LLMs) still struggle with long contexts due to memory limitations and their inability to tackle complex and long-context tasks. Additionally, LLMs often suffer from a lack of transparency…

计算与语言 · 计算机科学 2025-08-29 Zhirui Chen , Wei Shen , Jiashui Huang , Ling Shao

Diagnostic prediction and clinical reasoning are critical tasks in healthcare applications. While Large Language Models (LLMs) have shown strong capabilities in commonsense reasoning, they still struggle with diagnostic reasoning due to…