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Background: Spatial transcriptomics have emerged as a powerful tool in biomedical research because of its ability to capture both the spatial contexts and abundance of the complete RNA transcript profile in organs of interest. However,…

基因组学 · 定量生物学 2025-04-18 Shuo Shuo Liu , Shikun Wang , Yuxuan Chen , Anil K. Rustgi , Ming Yuan , Jianhua Hu

The Matrix Element Method (MEM) is a powerful method to extract information from measured events at collider experiments. Compared to multivariate techniques built on large sets of experimental data, the MEM does not rely on an…

高能物理 - 实验 · 物理学 2021-04-07 Florian Bury , Christophe Delaere

A novel approach is proposed, where energy filtered electrons, carrying both chemical identity and electrical information, serve as fine and flexible electrodes in direct electrical measurements. The method, termed 'chemically resolved…

材料科学 · 物理学 2009-11-10 Hagai Cohen

Scanning Transmission Electron Microscopy (STEM) offers high-resolution images that are used to quantify the nanoscale atomic structure and composition of materials and biological specimens. In many cases, however, the resolution is limited…

信号处理 · 电气工程与系统科学 2021-12-23 Daniel Nicholls , Alex Robinson , Jack Wells , Amirafshar Moshtaghpour , Mounib Bahri , Angus Kirkland , Nigel Browning

We propose a novel method to train deep convolutional neural networks which learn from multiple data sets of varying input sizes through weight sharing. This is an advantage in chemometrics where individual measurements represent exact…

机器学习 · 统计学 2019-11-11 Jacob Søgaard Larsen , Line Clemmensen

The chemical master equation (CME), which describes the discrete and stochastic molecule number dynamics associated with biological processes like transcription, is difficult to solve analytically. It is particularly hard to solve for…

亚细胞过程 · 定量生物学 2021-03-23 John J. Vastola , Gennady Gorin , Lior Pachter , William R. Holmes

Deep learning (DL) based channel estimation (CE) and multiple input and multiple output detection (MIMODet), as two separate research topics, have provided convinced evidence to demonstrate the effectiveness and robustness of artificial…

信号处理 · 电气工程与系统科学 2024-01-30 Xiangzhao Qin , Sha Hu , Jiankun Zhang , Jing Qian , Hao Wang

This study presents an innovative approach to predicting VCSEL emission characteristics using transformer neural networks. We demonstrate how to modify the transformer neural network for applications in physics. Our model achieved high…

无序系统与神经网络 · 物理学 2025-09-17 Aleksei V. Belonovskii , Elizaveta I. Girshova , Erkki Lähderanta , Mikhail Kaliteevski

Neural methods of molecule property prediction require efficient encoding of structure and property relationship to be accurate. Recent work using graph algorithms shows limited generalization in the latent molecule encoding space. We build…

定量方法 · 定量生物学 2020-11-26 Prateeth Nayak , Andrew Silberfarb , Ran Chen , Tulay Muezzinoglu , John Byrnes

Electron Cryo-Tomography (ECT) enables 3D visualization of macromolecule structure inside single cells. Macromolecule classification approaches based on convolutional neural networks (CNN) were developed to separate millions of…

定量方法 · 定量生物学 2018-03-28 Jialiang Guo , Bo Zhou , Xiangrui Zeng , Zachary Freyberg , Min Xu

We report on the design, commissioning, and initial measurements of a Transition-edge Sensor (TES) x-ray spectrometer for the Electron Beam Ion Trap (EBIT) at the National Institute of Standards and Technology (NIST). Over the past few…

Objective: This paper investigates how generative models, trained on ground-truth images, can be used \changes{as} priors for inverse problems, penalizing reconstructions far from images the generator can produce. The aim is that learned…

图像与视频处理 · 电气工程与系统科学 2023-08-07 Margaret Duff , Ivor J. A. Simpson , Matthias J. Ehrhardt , Neill D. F. Campbell

Partial Differential Equations (PDEs) are fundamental for modeling physical systems, yet solving them in a generic and efficient manner using machine learning-based approaches remains challenging due to limited multi-input and multi-scale…

机器学习 · 计算机科学 2025-08-12 Yichen Luo , Jia Wang , Dapeng Lan , Yu Liu , Zhibo Pang

Indirect structural health monitoring (iSHM) for broken rail detection using onboard sensors presents a cost-effective paradigm for railway track assessment, yet reliably detecting small, transient anomalies (2-10 cm) remains a significant…

机器学习 · 计算机科学 2025-10-10 Sizhe Ma , Katherine A. Flanigan , Mario Bergés , James D. Brooks

Dynamic Contrast Enhanced Magnetic Resonance Imaging aids in the detection and assessment of tumor aggressiveness by using a Gadolinium-based contrast agent (GBCA). However, GBCA is known to have potential toxic effects. This risk can be…

图像与视频处理 · 电气工程与系统科学 2024-02-06 Sadhana S , Sriprabha Ramanarayanan , Arunima Sarkar , Matcha Naga Gayathri , Keerthi Ram , Mohanasankar Sivaprakasam

Editing model parameters directly in Transformers makes updating open-source transformer-based models possible without re-training (Meng et al., 2023). However, these editing methods have only been evaluated on statements about encyclopedic…

Medical image segmentation have drawn massive attention as it is important in biomedical image analysis. Good segmentation results can assist doctors with their judgement and further improve patients' experience. Among many available…

图像与视频处理 · 电气工程与系统科学 2021-09-20 Youyang Sha , Yonghong Zhang , Xuquan Ji , Lei Hu

Magnetic Resonance Imaging (MRI) is one of the most flexible and powerful medical imaging modalities. This flexibility does however come at a cost; MRI images acquired at different sites and with different parameters exhibit significant…

Emotion recognition in conversations (ERC), the task of recognizing the emotion of each utterance in a conversation, is crucial for building empathetic machines. Existing studies focus mainly on capturing context- and speaker-sensitive…

人工智能 · 计算机科学 2023-11-01 Hui Ma , Jian Wang , Hongfei Lin , Bo Zhang , Yijia Zhang , Bo Xu

A propagator-based approach is investigated for Monte-Carlo (MC) modeling of neutral particles transport in fusion boundary plasmas. The propagator is essentially a Green function for the neutral kinetic equation, which depends on the…

等离子体物理 · 物理学 2026-02-03 M. V. Umansky , G. J. Parker , R. D. Smirnov