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In this paper, we study achievable rates of concatenated coding schemes over a deoxyribonucleic acid (DNA) storage channel. Our channel model incorporates the main features of DNA-based data storage. First, information is stored on many,…

信息论 · 计算机科学 2020-05-04 Andreas Lenz , Lorenz Welter , Sven Puchinger

DNA synthesis is considered as one of the most expensive components in current DNA storage systems. In this paper, focusing on a common synthesis machine, which generates multiple DNA strands in parallel following a fixed supersequence,we…

信息论 · 计算机科学 2025-05-13 Yajuan Liu , Tolga M. Duman

As a medium for cold data storage, DNA stands out as it promises significant gains in storage capacity and lifetime. However, it comes with its own data processing challenges to overcome. Constrained codes over the DNA alphabet…

信息论 · 计算机科学 2025-10-08 Canberk İrimağzı , Ahmed Hareedy

DNA Data storage has recently attracted much attention due to its durable preservation and extremely high information density (bits per gram) properties. In this work, we propose a hybrid coding strategy comprising of generalized…

信息论 · 计算机科学 2021-12-20 Yixin Wang , Li Deng , Md. Noor-A-Rahim , Erry Gunawan , Yong L. Guan , Zhi P. Shi , Chueh L. Poh

We study the amount of reliable information that can be stored in a DNA-based storage system with noisy sequencing, where each codeword is composed of short DNA molecules. We analyze a concatenated coding scheme, where the outer code is…

信息论 · 计算机科学 2026-05-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas

The yearly global production of data is growing exponentially, outpacing the capacity of existing storage media, such as tape and disk, and surpassing our ability to store it. DNA storage - the representation of arbitrary information as…

定量方法 · 定量生物学 2023-10-04 Thomas Heinis , Roman Sokolovskii , Jamie J. Alnasir

DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…

信息论 · 计算机科学 2025-04-22 Ruiying Cao , Xin Chen

DNA exhibits remarkable potential as a data storage solution due to its impressive storage density and long-term stability, stemming from its inherent biomolecular structure. However, developing this novel medium comes with its own set of…

图像与视频处理 · 电气工程与系统科学 2023-09-14 Trung Hieu Le , Xavier Pic , Jeremy Mateos , Marc Antonini

As a possible implementation of data storage using DNA, multiple strands of DNA are stored in a liquid container so that, in the future, they can be read by an array of DNA readers in parallel. These readers will sample the strands with…

信息论 · 计算机科学 2024-09-04 Hsin-Po Wang , Venkatesan Guruswami

With the rapid increase of available digital data, DNA storage is identified as a storage media with high density and capability of long-term preservation, especially for archival storage systems. However, the encoding density (i.e., how…

新兴技术 · 计算机科学 2021-08-26 Bingzhe Li , Li Ou , David Du

DNA strands serve as a storage medium for $4$-ary data over the alphabet $\{A,T,G,C\}$. DNA data storage promises formidable information density, long-term durability, and ease of replicability. However, information in this intriguing…

信息论 · 计算机科学 2024-08-06 Canberk İrimağzı , Yusuf Uslan , Ahmed Hareedy

Genome sequence analysis, which examines the DNA sequences of organisms, drives advances in many critical medical and biotechnological fields. Given its importance and the exponentially growing volumes of genomic sequence data, there are…

Due to their sequential nature, traditional DNA synthesis methods are expensive in terms of time and resources. They also fabricate multiple copies of the same strand, introducing redundancy. This redundancy can be leveraged to enhance the…

信息论 · 计算机科学 2025-10-29 Frederik Walter , Yonatan Yehezkeally

Motivation: Network-based analyses of omics data are widely used, and while many of these methods have been adapted to single-cell scenarios, they often remain memory- and space-intensive. As a result, they are better suited to batch data…

机器学习 · 计算机科学 2025-04-16 Pedro Henrique da Costa Avelar , Min Wu , Sophia Tsoka

In the current era, DeoxyriboNucleic Acid (DNA) based data storage emerges as an intriguing approach, garnering substantial academic interest and investigation. This paper introduces a novel deep joint source-channel coding (DJSCC) scheme…

新兴技术 · 计算机科学 2023-11-03 Wenfeng Wu , Luping Xiang , Qiang Liu , Kun Yang

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

新兴技术 · 计算机科学 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

Multimodal Large Language Models have demonstrated remarkable capabilities in video understanding, yet face prohibitive computational costs and performance degradation from ''context rot'' due to massive visual token redundancy. Existing…

计算机视觉与模式识别 · 计算机科学 2026-03-30 Shida Wang , YongXiang Hua , Zhou Tao , Haoyu Cao , Linli Xu

Remarkable achievements have been attained by deep neural networks in various applications. However, the increasing depth and width of such models also lead to explosive growth in both storage and computation, which has restricted the…

机器学习 · 计算机科学 2019-06-11 Linfeng Zhang , Zhanhong Tan , Jiebo Song , Jingwei Chen , Chenglong Bao , Kaisheng Ma

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

定量方法 · 定量生物学 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

We provide an overview of current approaches to DNA-based storage system design and accompanying synthesis, sequencing and editing methods. We also introduce and analyze a suite of new constrained coding schemes for both archival and random…