相关论文: Protein Autoregressive Modeling via Multiscale Str…

Autoregressive networks can achieve promising performance in many sequence modeling tasks with short-range dependence. However, when handling high-dimensional inputs and outputs, the huge amount of parameters in the network lead to…

Prior work on fine-grained image recognition (FGIR) has established the importance of the backbone selection, but has neglected the accuracy-vs-cost trade-offs under different training and evaluation settings. In this work we conduct a…

Visual autoregressive modeling, based on the next-scale prediction paradigm, exhibits notable advantages in image quality and model scalability over traditional autoregressive and diffusion models. It generates images by progressively…

The protein backbone is described as a smooth curved and twisted line in three-dimensional (3D) space and characterized by its curvature $\kappa(s)$ and torsion $\tau(s)$ both expressed as a function of arc length s. It is shown that the…

Autoregressive (AR) language models generate text one token at a time, even when consecutive tokens are highly predictable given earlier context. We introduce MARS (Mask AutoRegreSsion), a lightweight fine-tuning method that teaches an…

In recent years, deep learning techniques have made significant strides in molecular generation for specific targets, driving advancements in drug discovery. However, existing molecular generation methods present significant limitations:…

We present FrameFlow, a method for fast protein backbone generation using SE(3) flow matching. Specifically, we adapt FrameDiff, a state-of-the-art diffusion model, to the flow-matching generative modeling paradigm. We show how flow…

Industrial CAD workflows require robust, generalizable 3D geometric representations supporting accuracy and explainability. We introduce Shape, a self-supervised foundation model converting surface meshes into dense per-token embeddings.…

Protein structure prediction and folding are fundamental to understanding biology, with recent deep learning advances reshaping the field. Diffusion-based generative models have revolutionized protein design, enabling the creation of novel…

Tokenization is a promising path to multi-modal models capable of jointly understanding protein sequences, structure, and function. Existing protein structure tokenizers create tokens by pooling information from local neighborhoods, an…

With the advancement of deep learning techniques, the performance of Automatic Program Repair(APR) techniques has reached a new level. Previous deep learning-based APR techniques essentially modified program sentences in the…

While visual autoregressive modeling (VAR) strategies have shed light on image generation with the autoregressive models, their potential for segmentation, a task that requires precise low-level spatial perception, remains unexplored.…

Controllable image synthesis, which enables fine-grained control over generated outputs, has emerged as a key focus in visual generative modeling. However, controllable generation remains challenging for Visual Autoregressive (VAR) models…

Autoregressive models are widely used for tasks such as image and audio generation. The sampling process of these models, however, does not allow interruptions and cannot adapt to real-time computational resources. This challenge impedes…

Powerful priors allow us to perform inference with insufficient information. In this paper, we propose an autoregressive prior for 3D shapes to solve multimodal 3D tasks such as shape completion, reconstruction, and generation. We model the…

Deep learning is catalyzing a scientific revolution fueled by big data, accessible toolkits, and powerful computational resources, impacting many fields including protein structural modeling. Protein structural modeling, such as predicting…

Recent text-to-image models produce high-quality results but still struggle with precise visual control, balancing multimodal inputs, and requiring extensive training for complex multimodal image generation. To address these limitations, we…

Deep learning has transformed protein design, enabling accurate structure prediction, sequence optimization, and de novo protein generation. Advances in single-chain protein structure prediction via AlphaFold2, RoseTTAFold, ESMFold, and…

Directly generating 3D meshes, the default representation for 3D shapes in the graphics industry, using auto-regressive (AR) models has become popular these days, thanks to their sharpness, compactness in the generated results, and ability…

Automatic segmentation of the musculoskeletal system in pediatric magnetic resonance (MR) images is a challenging but crucial task for morphological evaluation in clinical practice. We propose a deep learning-based regularized segmentation…