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Diffusion models can be improved with additional guidance towards more effective representations of input. Indeed, prior empirical work has already shown that aligning internal representations of the diffusion model with those of…

机器学习 · 计算机科学 2025-10-14 Chenyu Wang , Cai Zhou , Sharut Gupta , Zongyu Lin , Stefanie Jegelka , Stephen Bates , Tommi Jaakkola

Masked diffusion models (MDMs) have emerged as a promising alternative to autoregressive models, enabling parallel token generation while achieving competitive performance. Despite these advantages, MDMs face a fundamental limitation: once…

Discrete diffusion models are increasingly competitive for language modeling, yet it remains unclear how their denoising objectives organize learning. Although these objectives target the full data distribution, we show that the exact…

机器学习 · 计算机科学 2026-05-15 Adrian Müller , Antoine Gonon , Zebang Shen , Ya-Ping Hsieh , Niao He

Deformable image registration aims to precisely align medical images from different modalities or times. Traditional deep learning methods, while effective, often lack interpretability, real-time observability and adjustment capacity during…

计算机视觉与模式识别 · 计算机科学 2024-10-08 Yongtai Zhuo , Yiqing Shen

Autoregressive models (ARMs) are hindered by slow sequential inference. While masked diffusion models (MDMs) offer a parallel alternative, they suffer from critical drawbacks: high computational overhead from precluding Key-Value (KV)…

计算与语言 · 计算机科学 2026-03-06 Jia-Nan Li , Jian Guan , Wei Wu , Chongxuan Li

Discrete diffusion models have recently shown significant progress in modeling complex data, such as natural languages and DNA sequences. However, unlike diffusion models for continuous data, which can generate high-quality samples in just…

机器学习 · 计算机科学 2025-03-20 Anji Liu , Oliver Broadrick , Mathias Niepert , Guy Van den Broeck

We propose SDAR, a Synergistic Diffusion-Autoregression paradigm that unifies the training efficiency of autoregressive models with the parallel inference capability of diffusion. Instead of costly end-to-end diffusion training, SDAR…

机器学习 · 计算机科学 2025-10-21 Shuang Cheng , Yihan Bian , Dawei Liu , Linfeng Zhang , Qian Yao , Zhongbo Tian , Wenhai Wang , Qipeng Guo , Kai Chen , Biqing Qi , Bowen Zhou

Single-cell RNA sequencing (scRNA-seq) enables the study of cellular heterogeneity. Yet, clustering accuracy, and with it downstream analyses based on cell labels, remain challenging due to measurement noise and biological variability. In…

机器学习 · 计算机科学 2026-03-03 Dominik Meier , Shixing Yu , Sagnik Nandy , Promit Ghosal , Kyra Gan

A central goal in systems biology and drug discovery is to predict the transcriptional response of cells to perturbations. This task is challenging due to the noisy and sparse nature of single-cell measurements, as well as the fact that…

定量方法 · 定量生物学 2026-02-10 Chenglei Yu , Chuanrui Wang , Bangyan Liao , Tailin Wu

Diffusion models have excelled at generative tasks for both continuous and token-based domains, but their application to discrete ordinal data remains underdeveloped. We present CountsDiff, a diffusion framework designed to natively model…

Purpose: Biophysical tissue models are increasingly used in the interpretation of diffusion MRI (dMRI) data, with the potential to provide specific biomarkers of brain microstructural changes. However, the general Standard Model has…

Machine learning methods, such as diffusion models, are widely explored as a promising way to accelerate high-fidelity fluid dynamics computation via a super-resolution process from faster-to-compute low-fidelity input. However, existing…

计算工程、金融与科学 · 计算机科学 2025-12-24 Ruoyan Li , Zijie Huang , Haixin Wang , Guancheng Wan , Yizhou Sun , Wei Wang

Face recognition models embed a face image into a low-dimensional identity vector containing abstract encodings of identity-specific facial features that allow individuals to be distinguished from one another. We tackle the challenging task…

计算机视觉与模式识别 · 计算机科学 2023-10-03 Manuel Kansy , Anton Raël , Graziana Mignone , Jacek Naruniec , Christopher Schroers , Markus Gross , Romann M. Weber

Stepwise signals are ubiquitous in single-molecule detections, where abrupt changes in signal levels typically correspond to molecular conformational changes or state transitions. However, these features are inevitably obscured by noise,…

信号处理 · 电气工程与系统科学 2026-02-10 Xingdi Tong , Chenyu Wen

Recent studies have shown that the denoising process in (generative) diffusion models can induce meaningful (discriminative) representations inside the model, though the quality of these representations still lags behind those learned…

计算机视觉与模式识别 · 计算机科学 2025-06-19 Sihyun Yu , Sangkyung Kwak , Huiwon Jang , Jongheon Jeong , Jonathan Huang , Jinwoo Shin , Saining Xie

Diffusion models that are based on iterative denoising have been recently proposed and leveraged in various generation tasks like image generation. Whereas, as a way inherently built for continuous data, existing diffusion models still have…

计算与语言 · 计算机科学 2023-04-11 Jiaao Chen , Aston Zhang , Mu Li , Alex Smola , Diyi Yang

Subject-driven image generation aims to synthesize novel depictions of a specific subject across diverse contexts while preserving its core identity features. Achieving both strong identity consistency and high prompt diversity presents a…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Aditi Singhania , Arushi Jain , Krutik Malani , Riddhi Dhawan , Souymodip Chakraborty , Vineet Batra , Ankit Phogat

Privacy protection has become a top priority as the proliferation of AI techniques has led to widespread collection and misuse of personal data. Anonymization and visual identity information hiding are two important facial privacy…

计算机视觉与模式识别 · 计算机科学 2023-09-12 Xiao He , Mingrui Zhu , Dongxin Chen , Nannan Wang , Xinbo Gao

Augmentation for dense prediction typically relies on either sample mixing or generative synthesis. Mixing improves robustness but misaligned masks yield soft label ambiguity. Diffusion synthesis increases apparent diversity but, when…

计算机视觉与模式识别 · 计算机科学 2025-11-06 Pengyu Jie , Wanquan Liu , Rui He , Yihui Wen , Deyu Meng , Chenqiang Gao

We present Piva (Preserving Identity with Variational Score Distillation), a novel optimization-based method for editing images and 3D models based on diffusion models. Specifically, our approach is inspired by the recently proposed method…

计算机视觉与模式识别 · 计算机科学 2024-06-14 Duong H. Le , Tuan Pham , Aniruddha Kembhavi , Stephan Mandt , Wei-Chiu Ma , Jiasen Lu