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As a widely used weakly supervised learning scheme, modern multiple instance learning (MIL) models achieve competitive performance at the bag level. However, instance-level prediction, which is essential for many important applications,…

机器学习 · 计算机科学 2022-06-14 Hitesh Sapkota , Qi Yu

Accurately measuring protein-RNA binding affinity is crucial in many biological processes and drug design. Previous computational methods for protein-RNA binding affinity prediction rely on either sequence or structure features, unable to…

生物大分子 · 定量生物学 2025-01-06 Rong Han , Xiaohong Liu , Tong Pan , Jing Xu , Xiaoyu Wang , Wuyang Lan , Zhenyu Li , Zixuan Wang , Jiangning Song , Guangyu Wang , Ting Chen

Multiple Instance Learning (MIL) is a weak supervision learning paradigm that allows modeling of machine learning problems in which labels are available only for groups of examples called bags. A positive bag may contain one or more…

机器学习 · 计算机科学 2019-10-29 Amina Asif , Fayyaz ul Amir Afsar Minhas

The journey of reducing noise from distant supervision (DS) generated training data has been started since the DS was first introduced into the relation extraction (RE) task. For the past decade, researchers apply the multi-instance…

计算与语言 · 计算机科学 2021-06-22 Tao Chen , Haizhou Shi , Siliang Tang , Zhigang Chen , Fei Wu , Yueting Zhuang

MicroRNA (miRNA) are small non-coding RNAs that regulates the gene expression at the post-transcriptional level. Determining whether a sequence segment is miRNA is experimentally challenging. Also, experimental results are sensitive to the…

定量方法 · 定量生物学 2017-04-13 Jaya Thomas , Lee Sael

Multiple Instance Learning (MIL) is a weakly supervised learning problem where the aim is to assign labels to sets or bags of instances, as opposed to traditional supervised learning where each instance is assumed to be independent and…

机器学习 · 计算机科学 2022-02-24 Soumyasundar Pal , Antonios Valkanas , Florence Regol , Mark Coates

Model reduction, which aims to learn a simpler model of the original mixed integer linear programming (MILP), can solve large-scale MILP problems much faster. Most existing model reduction methods are based on variable reduction, which…

机器学习 · 计算机科学 2026-02-04 Jiajun Li , Yixuan Li , Ran Hou , Yu Ding , Shisi Guan , Jiahui Duan , Xiongwei Han , Tao Zhong , Vincent Chau , Weiwei Wu , Wanyuan Wang

Multiple instance learning (MIL) has emerged as a powerful framework for weakly supervised whole slide image (WSI) classification, enabling slide-level predictions without requiring detailed patch-level annotations. Despite its success, a…

计算机视觉与模式识别 · 计算机科学 2025-07-25 Bryan Wong , Mun Yong Yi

Pretrained transformer models have achieved state-of-the-art results in many tasks and benchmarks recently. Many state-of-the-art Language Models (LMs), however, do not scale well above the threshold of 512 input tokens. In specialized…

计算与语言 · 计算机科学 2022-12-01 Joel Niklaus , Daniele Giofré

Multitarget Tracking (MTT) is the problem of tracking the states of an unknown number of objects using noisy measurements, with important applications to autonomous driving, surveillance, robotics, and others. In the model-based Bayesian…

机器学习 · 计算机科学 2021-06-07 Juliano Pinto , Georg Hess , William Ljungbergh , Yuxuan Xia , Lennart Svensson , Henk Wymeersch

The whole slide image (WSI) classification is often formulated as a multiple instance learning (MIL) problem. Since the positive tissue is only a small fraction of the gigapixel WSI, existing MIL methods intuitively focus on identifying…

计算机视觉与模式识别 · 计算机科学 2023-12-22 Wenhao Tang , Sheng Huang , Xiaoxian Zhang , Fengtao Zhou , Yi Zhang , Bo Liu

Many objects in the real world are difficult to describe by a single numerical vector of a fixed length, whereas describing them by a set of vectors is more natural. Therefore, Multiple instance learning (MIL) techniques have been…

机器学习 · 计算机科学 2017-03-08 Tomas Pevny , Petr Somol

Multiple instance learning is qualified for many pattern recognition tasks with weakly annotated data. The combination of artificial neural network and multiple instance learning offers an end-to-end solution and has been widely utilized.…

计算机视觉与模式识别 · 计算机科学 2022-05-30 Jingjun Yi , Beichen Zhou

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

计算机视觉与模式识别 · 计算机科学 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Mixed-integer linear programming (MILP) is widely employed for modeling combinatorial optimization problems. In practice, similar MILP instances with only coefficient variations are routinely solved, and machine learning (ML) algorithms are…

最优化与控制 · 数学 2023-03-07 Qingyu Han , Linxin Yang , Qian Chen , Xiang Zhou , Dong Zhang , Akang Wang , Ruoyu Sun , Xiaodong Luo

Multiple Instance Learning (MIL) is a weakly-supervised problem in which one label is assigned to the whole bag of instances. An important class of MIL models is instance-based, where we first classify instances and then aggregate those…

图像与视频处理 · 电气工程与系统科学 2024-03-13 Łukasz Struski , Dawid Rymarczyk , Arkadiusz Lewicki , Robert Sabiniewicz , Jacek Tabor , Bartosz Zieliński

Discovery of microRNAs (miRNAs) relies on predictive models for characteristic features from miRNA precursors (pre-miRNAs). The short length of miRNA genes and the lack of pronounced sequence features complicate this task. To accommodate…

Despite being resource-intensive to train, 3D convolutional neural networks (CNNs) have been the standard approach to classify CT and MRI scans. Recent work suggests that deep multiple instance learning (MIL) may be a more efficient…

机器学习 · 计算机科学 2026-04-30 Ethan Harvey , Dennis Johan Loevlie , Amir Ali Satani , Wansu Chen , David M. Kent , Michael C. Hughes

Multiple Instance Learning (MIL) is a sub-domain of classification problems with positive and negative labels and a "bag" of inputs, where the label is positive if and only if a positive element is contained within the bag, and otherwise is…

机器学习 · 统计学 2023-10-30 Edward Raff , James Holt

In statistical learning, many problem formulations have been proposed so far, such as multi-class learning, complementarily labeled learning, multi-label learning, multi-task learning, which provide theoretical models for various real-world…

机器学习 · 计算机科学 2022-11-14 Daiki Suehiro , Eiji Takimoto