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Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

计算与语言 · 计算机科学 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

Users typically engage with LLMs interactively, yet most existing benchmarks evaluate them in a static, single-turn format, posing reliability concerns in interactive scenarios. We identify a key obstacle towards reliability: LLMs are…

Retrieval-Augmented Generation (RAG) grounds Large Language Models (LLMs) in external knowledge but often suffers from flat context representations and stateless retrieval, leading to unstable performance. We propose Stateful…

计算与语言 · 计算机科学 2026-04-17 Qi Dong , Ziheng Lin , Ning Ding

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Large language models (LLMs) have recently shown strong progress on scientific reasoning, yet two major bottlenecks remain. First, explicit retrieval fragments reasoning, imposing a hidden "tool tax" of extra tokens and steps. Second,…

Clinical diagnosis begins with doctor-patient interaction, during which physicians iteratively gather information, determine examination and refine differential diagnosis through patients' response. This dynamic clinical-reasoning process…

计算与语言 · 计算机科学 2025-12-30 Yuqi Tang , Jing Yu , Zichang Su , Kehua Feng , Zhihui Zhu , Libin Wang , Lei Liang , Qiang Zhang , Keyan Ding , Huajun Chen

The adoption of large language models (LLMs) in healthcare has attracted significant research interest. However, their performance in healthcare remains under-investigated and potentially limited, due to i) they lack rich domain-specific…

人工智能 · 计算机科学 2024-05-21 Zishan Gu , Fenglin Liu , Changchang Yin , Ping Zhang

Systematic reviews in medicine play a critical role in evidence-based decision-making by aggregating findings from multiple studies. A central bottleneck in automating this process is extracting numeric evidence and determining study-level…

人工智能 · 计算机科学 2026-01-26 Massimiliano Pronesti , Michela Lorandi , Paul Flanagan , Oisin Redmond , Anya Belz , Yufang Hou

Evaluating the clinical correctness and reasoning fidelity of automatically generated medical imaging reports remains a critical yet unresolved challenge. Existing evaluation methods often fail to capture the structured diagnostic logic…

人工智能 · 计算机科学 2026-01-26 Suzhong Fu , Jingqi Dong , Xuan Ding , Rui Sun , Yiming Yang , Shuguang Cui , Zhen Li

Agentic reasoning enables large reasoning models (LRMs) to dynamically acquire external knowledge, but yet optimizing the retrieval process remains challenging due to the lack of dense, principled reward signals. In this paper, we introduce…

人工智能 · 计算机科学 2026-02-10 Senkang Hu , Yong Dai , Yuzhi Zhao , Yihang Tao , Yu Guo , Zhengru Fang , Sam Tak Wu Kwong , Yuguang Fang

Diagnosing hepatic diseases accurately and interpretably is critical, yet it remains challenging in real-world clinical settings. Existing AI approaches for clinical diagnosis often lack transparency, structured reasoning, and…

人工智能 · 计算机科学 2026-03-06 Zheng Li , Jiayi Xu , Zhikai Hu , Hechang Chen , Lele Cong , Yunyun Wang , Shuchao Pang

Trustworthy biomedical question answering (QA) systems must not only provide accurate answers but also justify them with current, verifiable evidence. Retrieval-augmented approaches partially address this gap but lack mechanisms to…

计算与语言 · 计算机科学 2026-03-31 Yiqing Zhang , Xiaozhong Liu , Fabricio Murai

Across medical specialties, clinical practice is anchored in evidence-based guidelines that codify best studied diagnostic and treatment pathways. These pathways routinely fall short for the long tail of real-world care not covered by…

Formative feedback is central to effective learning, yet providing timely, individualised feedback at scale remains a persistent challenge. While recent work has explored the use of large language models (LLMs) to automate feedback, most…

人工智能 · 计算机科学 2026-04-01 Fares Fawzi , Seyed Parsa Neshaei , Marta Knezevic , Tanya Nazaretsky , Tanja Käser

Deep research agents powered by Large Language Models (LLMs) can perform multi-step reasoning, web exploration, and long-form report generation. However, most existing systems operate in an autonomous manner, assuming fully specified user…

计算与语言 · 计算机科学 2026-01-13 Yingchaojie Feng , Qiang Huang , Xiaoya Xie , Zhaorui Yang , Jun Yu , Wei Chen , Anthony K. H. Tung

Traditional AI-based healthcare systems often rely on single-modal data, limiting diagnostic accuracy due to incomplete information. However, recent advancements in foundation models show promising potential for enhancing diagnosis…

人工智能 · 计算机科学 2025-03-24 Sihan Wang , Suiyang Jiang , Yibo Gao , Boming Wang , Shangqi Gao , Xiahai Zhuang

Existing benchmarks for evaluating the clinical reasoning capabilities of large language models (LLMs) often lack a clear definition of "clinical reasoning" as a construct, fail to capture the full breadth of interdependent tasks within a…

Deep Research Agents (DRAs) aim to answer complex questions by searching the web, checking evidence, and synthesizing conclusions across heterogeneous sources. We introduce a category-theoretic framework for evaluating and improving such…

机器学习 · 计算机科学 2026-04-30 Shuoling Liu , Zhiquan Tan , Kun Yi , Hui Wu , Yihan Li , Jiangpeng Yan , Liyuan Chen , Kai Chen , Qiang Yang

Large visual language models (VLMs) have shown strong multi-modal medical reasoning ability, but most operate as end-to-end black boxes, diverging from clinicians' evidence-based, staged workflows and hindering clinical accountability.…

人工智能 · 计算机科学 2026-03-12 Yuexi Du , Jinglu Wang , Shujie Liu , Nicha C. Dvornek , Yan Lu

Reasoning machine reading comprehension (R-MRC) aims to answer complex questions that require discrete reasoning based on text. To support discrete reasoning, evidence, typically the concise textual fragments that describe question-related…

计算与语言 · 计算机科学 2021-10-27 Yongwei Zhou , Junwei Bao , Haipeng Sun , Jiahui Liang , Youzheng Wu , Xiaodong He , Bowen Zhou , Tiejun Zhao