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Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

机器学习 · 计算机科学 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

The joint optimization of the reconstruction and classification error is a hard non convex problem, especially when a non linear mapping is utilized. In order to overcome this obstacle, a novel optimization strategy is proposed, in which a…

Neural multivariate regression underpins a wide range of domains, including control, robotics, and finance, yet the geometry of its learned representations remains poorly characterized. While neural collapse has been shown to benefit…

机器学习 · 计算机科学 2026-05-11 George Andriopoulos , Zixuan Dong , Bimarsha Adhikari , Keith Ross

Model-based trees are used to find subgroups in data which differ with respect to model parameters. In some applications it is natural to keep some parameters fixed globally for all observations while asking if and how other parameters vary…

统计计算 · 统计学 2025-10-07 Heidi Seibold , Torsten Hothorn , Achim Zeileis

The objective of the study is to evaluate the efficiency of a multi layer neural network models built by combining Recurrent Neural Network(RNN) and Convolutional Neural Network(CNN) for solving the problem of classifying different types of…

计算机视觉与模式识别 · 计算机科学 2021-01-12 Indraneel Ghosh , Siddhant Kundu

Graph neural networks (GNNs) emerge as a powerful family of representation learning models on graphs. To derive node representations, they utilize a global model that recursively aggregates information from the neighboring nodes. However,…

机器学习 · 计算机科学 2021-11-04 Zemin Liu , Yuan Fang , Chenghao Liu , Steven C. H. Hoi

Recent works show that Generative Adversarial Networks (GANs) can be successfully applied to chest X-ray data augmentation for lung disease recognition. However, the implausible and distorted pathology features generated from the less than…

图像与视频处理 · 电气工程与系统科学 2020-01-23 Yunyan Xing , Zongyuan Ge , Rui Zeng , Dwarikanath Mahapatra , Jarrel Seah , Meng Law , Tom Drummond

Magnetic resonance imaging (MRI) is one of the best medical imaging modalities as it offers excellent spatial resolution and soft-tissue contrast. But, the usage of MRI is limited by its slow acquisition time, which makes it expensive and…

图像与视频处理 · 电气工程与系统科学 2019-08-27 Balamurali Murugesan , Vijaya Raghavan S , Kaushik Sarveswaran , Keerthi Ram , Mohanasankar Sivaprakasam

The generalised linear model (GLM) is a very important tool for analysing real data in biology, sociology, agriculture, engineering and many other application domain where the relationship between the response and explanatory variables may…

统计方法学 · 统计学 2016-07-04 Abhik Ghosh , Ayanendranath Basu

In this contribution we present a survey of concepts in localized model order reduction methods for parameterized partial differential equations. The key concept of localized model order reduction is to construct local reduced spaces that…

We present a new approach for physics-based computational modeling of diseased human lungs. Our main object is the development of a model that takes the novel step of incorporating the dynamics of airway recruitment/de-recruitment into an…

计算工程、金融与科学 · 计算机科学 2023-05-10 Carolin M. Geitner , Tobias Becher , Inéz Frerichs , Norbert Weiler , Jason H. T. Bates , Wolfgang A. Wall

In this paper, we investigate a semiparametric regression model under the context of treatment effects via a localized neural network (LNN) approach. Due to a vast number of parameters involved, we reduce the number of effective parameters…

计量经济学 · 经济学 2024-07-23 Jiti Gao , Fei Liu , Bin Peng , Yanrong Yang

Many real-world applications involve data from multiple modalities and thus exhibit the view heterogeneity. For example, user modeling on social media might leverage both the topology of the underlying social network and the content of the…

机器学习 · 计算机科学 2021-02-16 Lecheng Zheng , Yu Cheng , Hongxia Yang , Nan Cao , Jingrui He

Providing diagnostic feedback about growth is crucial to formative decisions such as targeted remedial instructions or interventions. This paper proposed a longitudinal higher-order diagnostic classification modeling approach for measuring…

统计方法学 · 统计学 2018-09-19 Peida Zhan , Hong Jiao , Dandan Liao

Effective management of Type 1 Diabetes requires continuous glucose monitoring and precise insulin adjustments to prevent hyperglycemia and hypoglycemia. With the growing adoption of wearable glucose monitors and mobile health applications,…

机器学习 · 计算机科学 2026-01-22 Giorgia Rigamonti , Mirko Paolo Barbato , Davide Marelli , Paolo Napoletano

Despite the recent success of Graph Neural Networks (GNNs), training GNNs on large graphs remains challenging. The limited resource capacities of the existing servers, the dependency between nodes in a graph, and the privacy concern due to…

机器学习 · 计算机科学 2022-03-15 Morteza Ramezani , Weilin Cong , Mehrdad Mahdavi , Mahmut T. Kandemir , Anand Sivasubramaniam

The identification of predictive biomarkers from a large scale of covariates for subgroup analysis has attracted fundamental attention in medical research. In this article, we propose a generalized penalized regression method with a novel…

统计方法学 · 统计学 2019-04-29 Chong Ma , Wenxuan Deng , Shuangge Ma , Ray Liu , Kevin Galinsky

Convolutional Neural Networks (CNN) possess many positive qualities when it comes to spatial raster data. Translation invariance enables CNNs to detect features regardless of their position in the scene. However, in some domains, like…

机器学习 · 计算机科学 2020-07-13 Arnas Uselis , Mantas Lukoševičius , Lukas Stasytis

High-dimensional, heterogeneous data with complex feature interactions pose significant challenges for traditional predictive modeling approaches. While Projection to Latent Structures (PLS) remains a popular technique, it struggles to…

机器学习 · 计算机科学 2025-10-21 Farwa Abbas , Hussain Ahmad , Claudia Szabo

Subgroup discovery is a local pattern mining technique to find interpretable descriptions of sub-populations that stand out on a given target variable. That is, these sub-populations are exceptional with regard to the global distribution.…

数据库 · 计算机科学 2017-09-26 Janis Kalofolias , Mario Boley , Jilles Vreeken
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