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Alzheimer's Dementia (AD) represents one of the most pressing challenges in the field of neurodegenerative disorders, with its progression analysis being crucial for understanding disease dynamics and developing targeted interventions.…

计算机视觉与模式识别 · 计算机科学 2024-07-10 Jacob Thrasher , Alina Devkota , Ahmed Tafti , Binod Bhattarai , Prashnna Gyawali

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

计算机视觉与模式识别 · 计算机科学 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment…

计算机视觉与模式识别 · 计算机科学 2020-04-07 Ahsan Bin Tufail , Qiu-Na Zhang , Yong-Kui Ma

As the prevalence of Alzheimer's disease (AD) rises, improving mechanistic insight from non-invasive biomarkers is increasingly critical. Recent work suggests that circuit-level brain alterations manifest as changes in…

神经与进化计算 · 计算机科学 2026-02-10 Szymon Mamoń , Max Talanov , Alessandro Crimi

Alzheimer's disease (AD) and sleep disorders exhibit a close association, where disruptions in sleep patterns often precede the onset of Mild Cognitive Impairment (MCI) and early-stage AD. This study delves into the potential of utilizing…

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that predominantly affects the elderly population and currently has no cure. Magnetic Resonance Imaging (MRI), as a non-invasive imaging technique, is essential for the…

图像与视频处理 · 电气工程与系统科学 2025-07-24 Xinyue Yang , Meiliang Liu , Yunfang Xu , Xiaoxiao Yang , Zhengye Si , Zijin Li , Zhiwen Zhao

Large-scale volumetric medical images with annotation are rare, costly, and time prohibitive to acquire. Self-supervised learning (SSL) offers a promising pre-training and feature extraction solution for many downstream tasks, as it only…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Ke Yu , Li Sun , Junxiang Chen , Max Reynolds , Tigmanshu Chaudhary , Kayhan Batmanghelich

Early diagnosis of Alzheimer's Disease (AD), particularly at the mild cognitive impairment stage, is essential for timely intervention. However, this process faces significant barriers, including reliance on subjective assessments and the…

计算机视觉与模式识别 · 计算机科学 2025-12-19 Changwei Wu , Yifei Chen , Yuxin Du , Jinying Zong , Jie Dong , Mingxuan Liu , Feiwei Qin , Yong Peng , Jin Fan , Changmiao Wang

Developing successful artificial intelligence systems in practice depends on both robust deep learning models and large, high-quality data. However, acquiring and labeling data can be prohibitively expensive and time-consuming in many…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Saba Dadsetan , Mohsen Hejrati , Shandong Wu , Somaye Hashemifar

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

机器学习 · 计算机科学 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

3D structural Magnetic Resonance Imaging (MRI) brain scans are commonly acquired in clinical settings to monitor a wide range of neurological conditions, including neurodegenerative disorders and stroke. While deep learning models have…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

The availability of large scale data with high quality ground truth labels is a challenge when developing supervised machine learning solutions for healthcare domain. Although, the amount of digital data in clinical workflows is increasing,…

图像与视频处理 · 电气工程与系统科学 2022-08-31 Sara Atito , Syed Muhammad Anwar , Muhammad Awais , Josef Kitler

Self-supervised learning (SSL) has emerged as a powerful technique for learning rich representations from unlabeled data. The data representations are able to capture many underlying attributes of data, and be useful in downstream…

机器学习 · 计算机科学 2023-12-01 Weicheng Zhu , Sheng Liu , Carlos Fernandez-Granda , Narges Razavian

Self-Supervised Learning (SSL) presents an exciting opportunity to unlock the potential of vast, untapped clinical datasets, for various downstream applications that suffer from the scarcity of labeled data. While SSL has revolutionized…

Alzheimer's disease (AD) diagnosis is complex, requiring the integration of imaging and clinical data for accurate assessment. While deep learning has shown promise in brain MRI analysis, it often functions as a black box, limiting…

图像与视频处理 · 电气工程与系统科学 2025-03-04 Yexiao He , Ziyao Wang , Yuning Zhang , Tingting Dan , Tianlong Chen , Guorong Wu , Ang Li

Alzheimer's disease (AD) is the leading cause of dementia, and its early detection is crucial for effective intervention, yet current diagnostic methods often fall short in sensitivity and specificity. This study aims to detect significant…

图像与视频处理 · 电气工程与系统科学 2024-11-01 Milla E. Nielsen , Mads Nielsen , Mostafa Mehdipour Ghazi

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

Alzheimer's disease detection requires expensive neuroimaging or invasive procedures, limiting accessibility. This study explores whether deep learning can enable non-invasive Alzheimer's disease detection through handwriting analysis.…

图像与视频处理 · 电气工程与系统科学 2025-08-19 Emanuele Nardone , Tiziana D'Alessandro , Francesco Fontanella , Claudio De Stefano

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

定量方法 · 定量生物学 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo
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