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Weakly supervised image segmentation with image-level labels has drawn attention due to the high cost of pixel-level annotations. Traditional methods using Class Activation Maps (CAMs) often highlight only the most discriminative regions,…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Qingchen Tang , Lei Fan , Maurice Pagnucco , Yang Song

H&E-to-IHC stain translation techniques offer a promising solution for precise cancer diagnosis, especially in low-resource regions where there is a shortage of health professionals and limited access to expensive equipment. Considering the…

图像与视频处理 · 电气工程与系统科学 2024-09-04 Song Wang , Zhong Zhang , Huan Yan , Ming Xu , Guanghui Wang

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

计算机视觉与模式识别 · 计算机科学 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data…

计算机视觉与模式识别 · 计算机科学 2026-05-07 Zhiling Yan , Sicheng Chen , Tianyi Zhang , Nan Ying , Yanli Lei , Guanglei Zhang

We introduce a multi-scale Image Super Resolution (ISR) method building on recent advances in Visual Auto-Regressive (VAR) modeling. VAR models break image tokenization into additive, gradually increasing scales, using Residual Quantization…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Isma Hadji , Enrique Sanchez , Adrian Bulat , Brais Martinez , Georgios Tzimiropoulos

Suboptimal generalization of machine learning models on unseen data is a key challenge which hampers the clinical applicability of such models to medical imaging. Although various methods such as domain adaptation and domain generalization…

图像与视频处理 · 电气工程与系统科学 2021-08-04 Rikiya Yamashita , Jin Long , Snikitha Banda , Jeanne Shen , Daniel L. Rubin

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

图像与视频处理 · 电气工程与系统科学 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Controllable image synthesis with user scribbles is a topic of keen interest in the computer vision community. In this paper, for the first time we study the problem of photorealistic image synthesis from incomplete and primitive human…

计算机视觉与模式识别 · 计算机科学 2022-08-18 Jaskirat Singh , Liang Zheng , Cameron Smith , Jose Echevarria

Recent advances in protein backbone generation have achieved promising results under structural, functional, or physical constraints. However, existing methods lack the flexibility for precise topology control, limiting navigation of the…

人工智能 · 计算机科学 2025-04-22 Zhengxi Lu , Shizhuo Cheng , Yuru Jiang , Yan Zhang , Min Zhang

Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…

计算机视觉与模式识别 · 计算机科学 2022-03-01 Steve Tsham Mpinda Ataky , Alessandro Lameiras Koerich

We present a new and versatile implementation of rapid and localized immunohistochemical staining of tissue sections. Immunohistochemistry (IHC) allows to detect specific proteins on tissue sections and comprises a sequence of specific…

组织与器官 · 定量生物学 2021-05-18 Robert D. Lovchik , David Taylor , Govind Kaigala

Histopathology slides are routinely marked by pathologists using permanent ink markers that should not be removed as they form part of the medical record. Often tumour regions are marked up for the purpose of highlighting features or other…

计算机视觉与模式识别 · 计算机科学 2019-05-14 Sharib Ali , Nasullah Khalid Alham , Clare Verrill , Jens Rittscher

The field of computational pathology has witnessed remarkable progress in the development of both task-specific predictive models and task-agnostic self-supervised vision encoders. However, despite the explosive growth of generative…

计算机视觉与模式识别 · 计算机科学 2023-12-14 Ming Y. Lu , Bowen Chen , Drew F. K. Williamson , Richard J. Chen , Kenji Ikamura , Georg Gerber , Ivy Liang , Long Phi Le , Tong Ding , Anil V Parwani , Faisal Mahmood

Photon Absorption Remote Sensing (PARS) enables label-free imaging of subcellular morphology by observing biomolecule specific absorption interactions. Coupled with deep-learning, PARS produces label-free virtual Hematoxylin and Eosin (H&E)…

Image inpainting is an ill-posed problem to recover missing or damaged image content based on incomplete images with masks. Previous works usually predict the auxiliary structures (e.g., edges, segmentation and contours) to help fill…

计算机视觉与模式识别 · 计算机科学 2022-08-26 Yongsheng Yu , Dawei Du , Libo Zhang , Tiejian Luo

The microscopic examination of surgical tissue remains a cornerstone of disease classification but relies on subjective interpretations and access to highly specialized experts, which can compromise accuracy and clinical care. While…

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Histopathological visualizations are a pillar of modern medicine and biological research. Surgical oncology relies exclusively on post-operative histology to determine definitive surgical success and guide adjuvant treatments. The current…

图像与视频处理 · 电气工程与系统科学 2022-04-04 Marian Boktor , Benjamin Ecclestone , Vlad Pekar , Deepak Dinakaran , John R. Mackey , Paul Fieguth , Parsin Haji Reza

Spatial Transcriptomics (ST) merges the benefits of pathology images and gene expression, linking molecular profiles with tissue structure to analyze spot-level function comprehensively. Predicting gene expression from histology images is a…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Chen Zhang , Yilu An , Ying Chen , Hao Li , Xitong Ling , Lihao Liu , Junjun He , Yuxiang Lin , Zihui Wang , Rongshan Yu

The generation of well-designed artwork is often quite time-consuming and assumes a high degree of proficiency on part of the human painter. In order to facilitate the human painting process, substantial research efforts have been made on…

计算机视觉与模式识别 · 计算机科学 2021-12-17 Jaskirat Singh , Cameron Smith , Jose Echevarria , Liang Zheng
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