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Clinical free-text data offers immense potential to improve population health research such as richer phenotyping, symptom tracking, and contextual understanding of patient care. However, these data present significant privacy risks due to…

Synthetic data generation is one approach for sharing individual-level data. However, to meet legislative requirements, it is necessary to demonstrate that the individuals' privacy is adequately protected. There is no consolidated standard…

In the realm of precision medicine, effective patient stratification and disease subtyping demand innovative methodologies tailored for multi-omics data. Clustering techniques applied to multi-omics data have become instrumental in…

机器学习 · 计算机科学 2024-01-30 Bastian Pfeifer , Christel Sirocchi , Marcus D. Bloice , Markus Kreuzthaler , Martin Urschler

Low-level texture feature/knowledge is also of vital importance for characterizing the local structural pattern and global statistical properties, such as boundary, smoothness, regularity, and color contrast, which may not be well addressed…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Deyi Ji , Feng Zhao , Hongtao Lu , Feng Wu , Jieping Ye

We consider a collaborative learning scenario in which multiple data-owners wish to jointly train a logistic regression model, while keeping their individual datasets private from the other parties. We propose COPML, a fully-decentralized…

机器学习 · 计算机科学 2020-11-05 Jinhyun So , Basak Guler , A. Salman Avestimehr

The integration of clinical data offers significant potential for the development of personalized medicine. However, its use is severely restricted by the General Data Protection Regulation (GDPR), especially for small cohorts with rare…

分布式、并行与集群计算 · 计算机科学 2025-10-30 Simon Süwer , Mai Khanh Mai , Christoph Klein , Nicola Götzenberger , Denis Dalić , Andreas Maier , Jan Baumbach

Machine learning requires a large volume of sample data, especially when it is used in high-accuracy medical applications. However, patient records are one of the most sensitive private information that is not usually shared among…

机器学习 · 计算机科学 2021-08-24 Yoo Jeong Ha , Minjae Yoo , Gusang Lee , Soyi Jung , Sae Won Choi , Joongheon Kim , Seehwan Yoo

With the huge influx of various data nowadays, extracting knowledge from them has become an interesting but tedious task among data scientists, particularly when the data come in heterogeneous form and have missing information. Many data…

机器学习 · 计算机科学 2017-05-11 Tsuyoshi Kato , Rachelle Rivero

Privacy-preserving techniques for distributed computation have been proposed recently as a promising framework in collaborative inter-domain network monitoring. Several different approaches exist to solve such class of problems, e.g.,…

网络与互联网体系结构 · 计算机科学 2011-01-31 Fabio Ricciato , Martin Burkhart

The Collaborative Research Cycle (CRC) is a National Institute of Standards and Technology (NIST) benchmarking program intended to strengthen understanding of tabular data deidentification technologies. Deidentification algorithms are…

密码学与安全 · 计算机科学 2024-03-04 Aniruddha Sen , Christine Task , Dhruv Kapur , Gary Howarth , Karan Bhagat

Bridging the gap between internal and external validity is crucial for heterogeneous treatment effect estimation. Randomised controlled trials (RCTs), favoured for their internal validity due to randomisation, often encounter challenges in…

统计方法学 · 统计学 2026-04-03 Evangelos Dimitriou , Edwin Fong , Jens Magelund Tarp , Karla Diaz-Ordaz , Brieuc Lehmann

Amidst rising appreciation for privacy and data usage rights, researchers have increasingly acknowledged the principle of data minimization, which holds that the accessibility, collection, and retention of subjects' data should be kept to…

密码学与安全 · 计算机科学 2021-10-22 Winston Chou

Discovering a meaningful symbolic expression that explains experimental data is a fundamental challenge in many scientific fields. We present a novel, open-source computational framework called Scientist-Machine Equation Detector (SciMED),…

机器学习 · 计算机科学 2023-03-02 Liron Simon Keren , Alex Liberzon , Teddy Lazebnik

In this paper, we propose coded Merkle tree (CMT), a novel hash accumulator that offers a constant-cost protection against data availability attacks in blockchains, even if the majority of the network nodes are malicious. A CMT is…

密码学与安全 · 计算机科学 2019-12-23 Mingchao Yu , Saeid Sahraei , Songze Li , Salman Avestimehr , Sreeram Kannan , Pramod Viswanath

Access to electronic health records (EHRs) for digital health research is often limited by privacy regulations and institutional barriers. Synthetic EHRs have been proposed as a way to enable safe and sovereign data sharing; however,…

In the context of cloud computing, services are held on cloud servers, where the clients send their data to the server and obtain the results returned by server. However, the computation, data and results are prone to tampering due to the…

密码学与安全 · 计算机科学 2025-04-17 Yancheng Zhang , Mengxin Zheng , Xun Chen , Jingtong Hu , Weidong Shi , Lei Ju , Yan Solihin , Qian Lou

Zero-Knowledge Proofs (ZKPs) are critical for privacy-preserving techniques and verifiable computation. Many ZKP protocols rely on key kernels such as the SumCheck protocol and Merkle Tree commitments to enable their key security…

硬件体系结构 · 计算机科学 2025-10-21 Jianqiao Mo , Alhad Daftardar , Joey Ah-Kiow , Kaiyue Guo , Benedikt Bünz , Siddharth Garg , Brandon Reagen

One of the challenges in developing deep learning algorithms for medical image segmentation is the scarcity of annotated training data. To overcome this limitation, data augmentation and semi-supervised learning (SSL) methods have been…

图像与视频处理 · 电气工程与系统科学 2020-09-02 Bram Ruijsink , Esther Puyol-Anton , Ye Li , Wenja Bai , Eric Kerfoot , Reza Razavi , Andrew P. King

Electrocardiograms (ECGs) are non-invasive diagnostic tools crucial for detecting cardiac arrhythmic diseases in clinical practice. While ECG Self-supervised Learning (eSSL) methods show promise in representation learning from unannotated…

信号处理 · 电气工程与系统科学 2024-07-03 Che Liu , Zhongwei Wan , Cheng Ouyang , Anand Shah , Wenjia Bai , Rossella Arcucci

Ability to quantify and predict progression of a disease is fundamental for selecting an appropriate treatment. Many clinical metrics cannot be acquired frequently either because of their cost (e.g. MRI, gait analysis) or because they are…

机器学习 · 统计学 2019-05-28 Guanyang Wang , Yumeng Zhang , Yong Deng , Xuxin Huang , Łukasz Kidziński