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Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

For years, semantic interoperability standards have sought to streamline the exchange of clinical data, yet their deployment remains time-consuming, resource-intensive, and technically challenging. To address this, we introduce a…

计算与语言 · 计算机科学 2025-07-08 Alvaro Riquelme , Pedro Costa , Catalina Martinez

Feature engineering for Electronic Health Records (EHR) is complicated by irregular observation intervals, variable measurement frequencies, and structural sparsity inherent to clinical time series. Existing automated methods either lack…

机器学习 · 计算机科学 2026-04-27 Hojjat Karami , David Atienza , Jean-Philippe Thiran , Anisoara Ionescu

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

计算与语言 · 计算机科学 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

We introduce SimBench, a benchmark designed to evaluate the proficiency of simulator-oriented LLMs (S-LLMs) in generating digital twins (DTs) that can be used in simulators for virtual testing. Given a collection of S-LLMs, this benchmark…

人工智能 · 计算机科学 2026-01-29 Jingquan Wang , Andrew Negrut , Hongyu Wang , Harry Zhang , Dan Negrut

Enhancing clinical decision support (CDS), reducing documentation burdens, and improving patient health literacy remain persistent challenges in digital health. This paper presents an open-source, agent-based framework that integrates Large…

软件工程 · 计算机科学 2025-06-18 Abul Ehtesham , Aditi Singh , Saket Kumar

Unstructured data in Electronic Health Records (EHRs) often contains critical information -- complementary to imaging -- that could inform radiologists' diagnoses. But the large volume of notes often associated with patients together with…

计算与语言 · 计算机科学 2024-06-12 Hiba Ahsan , Denis Jered McInerney , Jisoo Kim , Christopher Potter , Geoffrey Young , Silvio Amir , Byron C. Wallace

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

计算与语言 · 计算机科学 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang

Federated learning (FL) enables collaborative model training without sharing raw data, making it attractive for privacy-sensitive domains, e.g., healthcare, finance, and IoT. A major obstacle, however, is the potential heterogeneity of…

机器学习 · 计算机科学 2026-02-02 Abdelrhman Gaber , Muhammad ElMahdy , Youssif Abuzied , Hassan Abd-Eltawab , Tamer ElBatt

Objective: To enhance health literacy and accessibility of health information for a diverse patient population by developing a patient-centered artificial intelligence (AI) solution using large language models (LLMs) and Fast Healthcare…

计算机与社会 · 计算机科学 2024-02-06 Paul Schmiedmayer , Adrit Rao , Philipp Zagar , Vishnu Ravi , Aydin Zahedivash , Arash Fereydooni , Oliver Aalami

Surgical co-management (SCM) is an evidence-based model in which hospitalists jointly manage medically complex perioperative patients alongside surgical teams. Despite its clinical and financial value, SCM is limited by the need to manually…

Large language models (LLMs) are increasingly used to extract clinical data from electronic health records (EHRs), offering significant improvements in scalability and efficiency for real-world data (RWD) curation in oncology. However, the…

Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited. Existing benchmarks often rely on static datasets or…

计算与语言 · 计算机科学 2026-05-29 Valentina Bui Muti , Eugénie Dulout , Ziquan Fu

Electronic Health Record (EHR) tables pose unique challenges among which is the presence of hidden contextual dependencies between medical features with a high level of data dimensionality and sparsity. This study presents the first…

计算与语言 · 计算机科学 2025-01-17 Jesus Lovon , Martin Mouysset , Jo Oleiwan , Jose G. Moreno , Christine Damase-Michel , Lynda Tamine

Large language models (LLMs) such as GPT-4o and o1 have demonstrated strong performance on clinical natural language processing (NLP) tasks across multiple medical benchmarks. Nonetheless, two high-impact NLP tasks - structured tabular…

Missing-person and child-safety investigations rely on heterogeneous case documents, including structured forms, bulletin-style posters, and narrative web profiles. Variations in layout, terminology, and data quality impede rapid triage,…

计算与语言 · 计算机科学 2026-04-09 Joshua Castillo , Ravi Mukkamala

Electronic health records (EHRs) contain a vast amount of high-dimensional multi-modal data that can accurately represent a patient's medical history. Unfortunately, most of this data is either unstructured or semi-structured, rendering it…

计算与语言 · 计算机科学 2023-12-06 Ashwyn Sharma , David I. Feldman , Aneesh Jain

Objective: Large language models (LLMs) show promise for clinical discharge planning, but their use is constrained by hallucination, omissions, and miscalibrated confidence. We introduce a self-improving, cache-optional Planner-Auditor…

人工智能 · 计算机科学 2026-01-30 Kaiyuan Wu , Aditya Nagori , Rishikesan Kamaleswaran

Background: Patient recruitment in clinical trials is hindered by complex eligibility criteria and labor-intensive chart reviews. Prior research using text-only models have struggled to address this problem in a reliable and scalable way…

计算与语言 · 计算机科学 2025-03-20 Anatole Callies , Quentin Bodinier , Philippe Ravaud , Kourosh Davarpanah

In this study, we investigated the ability of the large language model (LLM) to enhance healthcare data interoperability. We leveraged the LLM to convert clinical texts into their corresponding FHIR resources. Our experiments, conducted on…

计算与语言 · 计算机科学 2023-10-23 Yikuan Li , Hanyin Wang , Halid Yerebakan , Yoshihisa Shinagawa , Yuan Luo
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