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Pathology Foundation Models (FMs) hold great promise for healthcare. Before they can be used in clinical practice, it is essential to ensure they are robust to variations between medical centers. We measure whether pathology FMs focus on…

机器学习 · 计算机科学 2025-02-04 Edwin D. de Jong , Eric Marcus , Jonas Teuwen

Pathology foundation models (PFMs) have emerged as powerful pretrained encoders for computational pathology, but their robustness under clinically relevant distribution shifts remains insufficiently understood. We benchmark the robustness…

图像与视频处理 · 电气工程与系统科学 2026-04-29 Fredrik K. Gustafsson , Mattias Rantalainen

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

计算机视觉与模式识别 · 计算机科学 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Computational pathology (CPath) has shown great potential in mining actionable insights from Whole Slide Images (WSIs). Deep Learning (DL) has been at the center of modern CPath, and while it delivers unprecedented performance, it is also…

定量方法 · 定量生物学 2025-07-31 Gianluca Carloni , Biagio Brattoli , Seongho Keum , Jongchan Park , Taebum Lee , Chang Ho Ahn , Sergio Pereira

Biomedical Foundation Models (FMs) are rapidly transforming AI-enabled healthcare research and entering clinical validation. However, their susceptibility to learning non-biological technical features -- including variations in…

Foundation models (FMs) promise to generalize medical imaging, but their effectiveness varies. It remains unclear how pre-training domain (medical vs. general), paradigm (e.g., text-guided), and architecture influence embedding quality,…

Due to the increase in computational resources and accessibility of data, an increase in large, deep learning models trained on copious amounts of multi-modal data using self-supervised or semi-supervised learning have emerged. These…

计算机视觉与模式识别 · 计算机科学 2024-04-30 Madeline Chantry Schiappa , Shehreen Azad , Sachidanand VS , Yunhao Ge , Ondrej Miksik , Yogesh S. Rawat , Vibhav Vineet

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

Foundation models (FMs) are changing the way medical images are analyzed by learning from large collections of unlabeled data. Instead of relying on manually annotated examples, FMs are pre-trained to learn general-purpose visual features…

Foundation models (FMs) are transforming computational pathology by offering new ways to analyze histopathology images. However, FMs typically require weeks of training on large databases, making their creation a resource-intensive process.…

图像与视频处理 · 电气工程与系统科学 2026-01-27 Till Nicke , Daniela Schacherer , Jan Raphael Schäfer , Natalia Artysh , Antje Prasse , André Homeyer , Andrea Schenk , Henning Höfener , Johannes Lotz

Wearable foundation models (WFMs), trained on large volumes of data collected by affordable, always-on devices, have demonstrated strong performance on short-term, well-defined health monitoring tasks, including activity recognition,…

Pathology foundation models (PFMs) have emerged as a core approach for learning transferable representations from whole slide images (WSIs), and they are typically benchmarked through downstream clinical endpoints. While such task level…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Bokai Zhao , Yiyang Zhang , Yuanchi Zhu , Hanqing Chao , Long Bai , Tai Ma , Minfeng Xu , Ming Song , Tianzi Jiang

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation),…

图像与视频处理 · 电气工程与系统科学 2026-02-05 Weiming Chen , Xitong Ling , Xidong Wang , Zhenyang Cai , Yijia Guo , Mingxi Fu , Ziyi Zeng , Minxi Ouyang , Jiawen Li , Yizhi Wang , Tian Guan , Benyou Wang , Yonghong He

Pathology foundation models (PFMs) have recently emerged as powerful pretrained encoders for computational pathology, enabling transfer learning across a wide range of downstream tasks. However, systematic comparisons of these models for…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Fredrik K. Gustafsson , Constance Boissin , Johan Vallon-Christersson , David A. Clifton , Mattias Rantalainen

Pathology has played a crucial role in the diagnosis and evaluation of patient tissue samples obtained from surgeries and biopsies for many years. The advent of Whole Slide Scanners and the development of deep learning technologies have…

计算机视觉与模式识别 · 计算机科学 2024-08-07 Mieko Ochi , Daisuke Komura , Shumpei Ishikawa

Foundation models (FMs) have emerged as a transformative paradigm in medical image analysis, offering the potential to provide generalizable, task-agnostic solutions across a wide range of clinical tasks and imaging modalities. Their…

计算机视觉与模式识别 · 计算机科学 2025-11-04 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

A vision foundation model outputs an embedding vector for an image, which can be affected by common editing operations (e.g., JPEG compression, brightness, contrast adjustments). These common perturbations alter embedding vectors and may…

密码学与安全 · 计算机科学 2026-04-17 Hongbin Liu , Zhengyuan Jiang , Cheng Hong , Neil Zhenqiang Gong

Foundation models, pre-trained on large image datasets and capable of capturing rich feature representations, have recently shown potential for zero-shot image registration. However, their performance has mostly been tested in the context…

图像与视频处理 · 电气工程与系统科学 2025-08-12 Hanxue Gu , Yaqian Chen , Nicholas Konz , Qihang Li , Maciej A. Mazurowski
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