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Diffusion-based large language models offer a non-autoregressive alternative for text generation, but enabling them to perform complex reasoning remains challenging. Reinforcement learning has recently emerged as an effective post-training…

人工智能 · 计算机科学 2026-04-14 Shaoan Xie , Lingjing Kong , Xiangchen Song , Xinshuai Dong , Guangyi Chen , Eric P. Xing , Kun Zhang

The reasoning capabilities of LLM (Large Language Model) are widely acknowledged in recent research, inspiring studies on tool learning and autonomous agents. LLM serves as the "brain" of the agent, orchestrating multiple tools for…

机器学习 · 计算机科学 2024-03-26 Xiangyan Liu , Rongxue Li , Wei Ji , Tao Lin

We introduce a pioneering methodology for boosting large language models in the domain of protein representation learning. Our primary contribution lies in the refinement process for correlating the over-reliance on co-evolution knowledge,…

人工智能 · 计算机科学 2024-12-05 Yaoyao Xu , Xinjian Zhao , Xiaozhuang Song , Benyou Wang , Tianshu Yu

Chain-of-Thought (CoT) prompting has shown promise in enhancing the reasoning capabilities of large language models (LLMs) by generating natural language (NL) rationales that lead to the final answer. However, it struggles with numerical…

人工智能 · 计算机科学 2025-02-13 Cheryl Li , Tianyuan Xu , Yiwen Guo

Large Language Models (LLMs) have revolutionized the field of natural language processing, but they fall short in comprehending biological sequences such as proteins. To address this challenge, we propose InstructProtein, an innovative LLM…

生物大分子 · 定量生物学 2023-10-06 Zeyuan Wang , Qiang Zhang , Keyan Ding , Ming Qin , Xiang Zhuang , Xiaotong Li , Huajun Chen

While deep learning techniques have shown promising results in many natural language processing (NLP) tasks, it has not been widely applied to the clinical domain. The lack of large datasets and the pervasive use of domain-specific language…

计算与语言 · 计算机科学 2019-06-20 Jiin Nam , Seunghyun Yoon , Kyomin Jung

Reinforcement learning (RL) has demonstrated strong potential in training large language models (LLMs) capable of complex reasoning for real-world problem solving. More recently, RL has been leveraged to create sophisticated LLM-based…

计算与语言 · 计算机科学 2025-05-22 Bowen Jin , Jinsung Yoon , Priyanka Kargupta , Sercan O. Arik , Jiawei Han

Large Language Models (LLMs) have demonstrated good performance in many reasoning tasks, but they still struggle with some complicated reasoning tasks including logical reasoning. One non-negligible reason for LLMs' suboptimal performance…

计算与语言 · 计算机科学 2024-04-09 Yanda Li , Dixuan Wang , Jiaqing Liang , Guochao Jiang , Qianyu He , Yanghua Xiao , Deqing Yang

Automated Theorem Proving (ATP) faces challenges due to its complexity and computational demands. Recent work has explored using Large Language Models (LLMs) for ATP action selection, but these methods can be resource-intensive. This study…

人工智能 · 计算机科学 2024-07-23 Mahdi Buali , Robert Hoehndorf

Large language models (LLMs) face persistent challenges when handling long-context tasks, most notably the lost in the middle issue, where information located in the middle of a long input tends to be underutilized. Some existing methods…

人工智能 · 计算机科学 2025-10-22 Song Yu , Xiaofei Xu , Ke Deng , Li Li , Lin Tian

Recent research on Reasoning of Large Language Models (LLMs) has sought to further enhance their performance by integrating meta-thinking -- enabling models to monitor, evaluate, and control their reasoning processes for more adaptive and…

人工智能 · 计算机科学 2025-05-28 Ziyu Wan , Yunxiang Li , Xiaoyu Wen , Yan Song , Hanjing Wang , Linyi Yang , Mark Schmidt , Jun Wang , Weinan Zhang , Shuyue Hu , Ying Wen

Large language models (LLMs) have achieved impressive performance on various reasoning tasks. To further improve the performance, we propose MultiTool-CoT, a novel framework that leverages chain-of-thought (CoT) prompting to incorporate…

计算与语言 · 计算机科学 2023-05-29 Tatsuro Inaba , Hirokazu Kiyomaru , Fei Cheng , Sadao Kurohashi

During Human Robot Interactions in disaster relief scenarios, Large Language Models (LLMs) have the potential for substantial physical reasoning to assist in mission objectives. However, these reasoning capabilities are often found only in…

计算与语言 · 计算机科学 2025-09-05 Mollie Shichman , Claire Bonial , Austin Blodgett , Taylor Hudson , Francis Ferraro , Rachel Rudinger

Reinforcement learning (RL) has emerged as a promising approach to improve large language model (LLM) reasoning, yet most open efforts focus narrowly on math and code, limiting our understanding of its broader applicability to general…

Protein language models (pLMs) pre-trained on vast protein sequence databases excel at various downstream tasks but often lack the structural knowledge essential for some biological applications. To address this, we introduce a method to…

Recent advancements in tool learning have enabled large language models (LLMs) to integrate external tools, enhancing their task performance by expanding their knowledge boundaries. However, relying on tools often introduces tradeoffs…

计算与语言 · 计算机科学 2025-03-11 Hongshen Xu , Zihan Wang , Zichen Zhu , Lei Pan , Xingyu Chen , Lu Chen , Kai Yu

We propose integration of reasoning into speech large language models (speechLLMs) for the end-to-end slot-filling task. Inspired by the recent development of reasoning LLMs, we use a chain-of-thought framework to decompose the slot-filling…

计算与语言 · 计算机科学 2026-02-04 Kadri Hacioglu , Manjunath K E , Andreas Stolcke

Legal Artificial Intelligence (LegalAI) has achieved notable advances in automating judicial decision-making with the support of Large Language Models (LLMs). However, existing legal LLMs still struggle to generate reliable and…

计算与语言 · 计算机科学 2026-02-10 Xin Dai , Buqiang Xu , Zhenghao Liu , Yukun Yan , Huiyuan Xie , Xiaoyuan Yi , Shuo Wang , Ge Yu

Large language model (LLM)-based systems are increasingly deployed to conduct scientific research autonomously, yet whether their reasoning adheres to the epistemic norms that make scientific inquiry self-correcting is poorly understood.…

We propose ProtLLM, a versatile cross-modal large language model (LLM) for both protein-centric and protein-language tasks. ProtLLM features a unique dynamic protein mounting mechanism, enabling it to handle complex inputs where the natural…

生物大分子 · 定量生物学 2024-03-14 Le Zhuo , Zewen Chi , Minghao Xu , Heyan Huang , Heqi Zheng , Conghui He , Xian-Ling Mao , Wentao Zhang