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Hydration status is a key physiological indicator associated with cellular homeostasis, renal function, and overall health. Recent advances in smart sensing environments enable passive monitoring of urinary biomarkers that can provide…

Quantitative ultrasound (QUS) offers a non-invasive and objective way to quantify tissue health. We recently presented a spatially adaptive regularization method for reconstruction of a single QUS parameter, limited to a two dimensional…

Accurate estimation of a user's biological joint moment from wearable sensor data is vital for improving exoskeleton control during real-world locomotor tasks. However, most state-of-the-art methods rely on deep learning techniques that…

机器人学 · 计算机科学 2026-03-10 Jimin An , Changseob Song , Eni Halilaj , Inseung Kang

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality. While COPD diagnosis is based on lung function tests, early stages and progression of different aspects of the disease can be visible and…

图像与视频处理 · 电气工程与系统科学 2019-09-30 Max Argus , Cornelia Schaefer-Prokop , David A. Lynch , Bram van Ginneken

Gaussian processes (GPs) are used to make medical and scientific decisions, including in cardiac care and monitoring of atmospheric carbon dioxide levels. Notably, the choice of GP kernel is often somewhat arbitrary. In particular,…

In recent years, a comprehensive study of multi-view datasets (e.g., multi-omics and imaging scans) has been a focus and forefront in biomedical research. State-of-the-art biomedical technologies are enabling us to collect multi-view…

机器学习 · 统计学 2020-04-30 Md Ashad Alam , Chuan Qiu , Hui Shen , Yu-Ping Wang , Hong-Wen Deng

The rate of convergence of weighted kernel herding (WKH) and sequential Bayesian quadrature (SBQ), two kernel-based sampling algorithms for estimating integrals with respect to some target probability measure, is investigated. Under…

机器学习 · 统计学 2021-11-02 Rajiv Khanna , Liam Hodgkinson , Michael W. Mahoney

Gaussian processes (GP) for machine learning have been studied systematically over the past two decades and they are by now widely used in a number of diverse applications. However, GP kernel design and the associated hyper-parameter…

机器学习 · 计算机科学 2020-10-28 Feng Yin , Lishuo Pan , Xinwei He , Tianshi Chen , Sergios Theodoridis , Zhi-Quan , Luo

We propose a quantum algorithm based on ridge regression model, which get the optimal fitting parameters w and a regularization hyperparameter {\alpha} by analysing the training dataset. The algorithm consists of two subalgorithms. One is…

量子物理 · 物理学 2021-04-28 Menghan Chen , Chaohua Yu , Gongde Guo , Song Lin

Quantitative MRI (qMRI) methods allow reducing the subjectivity of clinical MRI by providing numerical values on which diagnostic assessment or predictions of tissue properties can be based. However, qMRI measurements typically take more…

医学物理 · 物理学 2022-02-15 Matti Hanhela , Antti Paajanen , Mikko J. Nissi , Ville Kolehmainen

High-resolution (HR) quantitative MRI (qMRI) relaxometry provides objective tissue characterization but remains clinically underutilized due to lengthy acquisition times. We propose a physics-informed, self-supervised framework for qMRI…

计算机视觉与模式识别 · 计算机科学 2025-12-22 Alireza Samadifardheris , Dirk H. J. Poot , Florian Wiesinger , Stefan Klein , Juan A. Hernandez-Tamames

Certain cancer types, notably pancreatic cancer, are difficult to detect at an early stage, motivating robust biomarker-based screening. Liquid biopsies enable non-invasive monitoring of circulating biomarkers, but typical machine learning…

机器学习 · 计算机科学 2025-11-21 Chongmin Lee , Jihie Kim

Along with rich health-related metadata, medical images have been acquired for over 40,000 male and female UK Biobank participants, aged 44-82, since 2014. Phenotypes derived from these images, such as measurements of body composition from…

图像与视频处理 · 电气工程与系统科学 2021-09-16 Taro Langner , Fredrik K. Gustafsson , Benny Avelin , Robin Strand , Håkan Ahlström , Joel Kullberg

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Multimodal imaging has transformed neuroscience research. While it presents unprecedented opportunities, it also imposes serious challenges. Particularly, it is difficult to combine the merits of the interpretability attributed to a simple…

统计方法学 · 统计学 2021-11-25 Xiaowu Dai , Lexin Li

A major challenge in machine learning is the computational expense of training these models. Model training can be viewed as a form of optimization used to fit a machine learning model to a set of data, which can take up significant amount…

机器学习 · 计算机科学 2021-11-16 Prasanna Date , Thomas Potok

Foundation models pretrained on large-scale histopathology data have found great success in various fields of computational pathology, but their impact on regressive biomarker prediction remains underexplored. In this work, we…

计算机视觉与模式识别 · 计算机科学 2026-02-06 Alexander Blezinger , Wolfgang Nejdl , Ming Tang

Instant machine learning predictions of molecular properties are desirable for materials design, but the predictive power of the methodology is mainly tested on well-known benchmark datasets. Here, we investigate the performance of machine…

Advances in classical machine learning and single-cell technologies have paved the way to understand interactions between disease cells and tumor microenvironments to accelerate therapeutic discovery. However, challenges in these machine…

量子物理 · 物理学 2023-10-18 Anupama Ray , Dhiraj Madan , Srushti Patil , Maria Anna Rapsomaniki , Pushpak Pati

Effective molecular representations are essential for ligand-based virtual screening. We investigate how quantum data embedding strategies can improve this task by developing and evaluating a family of quantum-classical hybrid embedding…

量子物理 · 物理学 2025-12-19 Junggu Choi , Tak Hur , Seokhoon Jeong , Kyle L. Jung , Jun Bae Park , Junho Lee , Jae U. Jung , Daniel K. Park