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Background. Coronary artery calcium (CAC) is a powerful predictor of major adverse cardiovascular events (MACE). Traditional Agatston score simply sums the calcium, albeit in a non-linear way, leaving room for improved calcification…

Continuous Conditional Diffusion Model (CCDM) is a diffusion-based framework designed to generate high-quality images conditioned on continuous regression labels. Although CCDM has demonstrated clear advantages over prior approaches across…

计算机视觉与模式识别 · 计算机科学 2026-02-03 Xin Ding , Yun Chen , Sen Zhang , Kao Zhang , Nenglun Chen , Peibei Cao , Yongwei Wang , Fei Wu

Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…

医学物理 · 物理学 2025-09-23 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Coronary artery calcification (CAC) is a strong predictor of cardiovascular events, with CT-based Agatston scoring widely regarded as the clinical gold standard. However, CT is costly and impractical for large-scale screening, while chest…

计算机视觉与模式识别 · 计算机科学 2026-01-07 Dylan Saeed , Ramtin Gharleghi , Susann Beier , Sonit Singh

Cone-beam computed tomography (CBCT) images are problematic in clinical medicine because of their low contrast and high artifact content compared with conventional CT images. Although there are some studies to improve image quality, in…

图像与视频处理 · 电气工程与系统科学 2026-03-30 Naruki Murahashi , Mitsuhiro Nakamura , Megumi Nakao

Non-contrast computed tomography calcium scoring (CTCS) is widely recognized as an effective tool for cardiovascular risk stratification. This study aimed to develop a novel machine learning framework for predicting myocardial ischemia from…

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

计算机视觉与模式识别 · 计算机科学 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Cardiovascular disease (CVD) is the global leading cause of death. A strong risk factor for CVD events is the amount of coronary artery calcium (CAC). To meet demands of the increasing interest in quantification of CAC, i.e. coronary…

计算机视觉与模式识别 · 计算机科学 2021-09-09 Bob D. de Vos , Jelmer M. Wolterink , Tim Leiner , Pim A. de Jong , Nikolas Lessmann , Ivana Isgum

Heavy smokers undergoing screening with low-dose chest CT are affected by cardiovascular disease as much as by lung cancer. Low-dose chest CT scans acquired in screening enable quantification of atherosclerotic calcifications and thus…

计算机视觉与模式识别 · 计算机科学 2018-02-06 Nikolas Lessmann , Bram van Ginneken , Majd Zreik , Pim A. de Jong , Bob D. de Vos , Max A. Viergever , Ivana Išgum

Anterior segment optical coherence tomography (AS-OCT) is a non-invasive imaging technique that is highly valuable for ophthalmic diagnosis. However, speckles in AS-OCT images can often degrade the image quality and affect clinical…

图形学 · 计算机科学 2023-07-03 Li Sanqian , Higashita Risa , Fu Huazhu , Li Heng , Niu Jingxuan , Liu Jiang

Purpose: In this study, the recently emerged advances in Fuzzy Cognitive Maps (FCM) are investigated and employed, for achieving the automatic and non-invasive diagnosis of Coronary Artery Disease (CAD). Methods: A Computer-Aided Diagnostic…

人工智能 · 计算机科学 2021-05-04 Ioannis D. Apostolopoulos , Peter P. Groumpos , Dimitris I. Apostolopoulos

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…

图像与视频处理 · 电气工程与系统科学 2023-10-10 Md Selim , Jie Zhang , Faraneh Fathi , Michael A. Brooks , Ge Wang , Guoqiang Yu , Jin Chen

During the process of computed tomography (CT), metallic implants often cause disruptive artifacts in the reconstructed images, impeding accurate diagnosis. Several supervised deep learning-based approaches have been proposed for reducing…

图像与视频处理 · 电气工程与系统科学 2024-01-08 Xuan Liu , Yaoqin Xie , Songhui Diao , Shan Tan , Xiaokun Liang

Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging…

CAD remains a major global public health burden, yet scalable screening tools are limited. Although CCTA is a first-line non-invasive diagnostic modality, its use is constrained by resource requirements and radiation exposure. AI-ECG may…

Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

图像与视频处理 · 电气工程与系统科学 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts

High failure rates in cardiac drug development necessitate virtual clinical trials via electrocardiogram (ECG) generation to reduce risks and costs. However, existing ECG generation models struggle to balance morphological realism with…

机器学习 · 计算机科学 2026-03-31 Qian Shao , Bang Du , Zepeng Li , Qiyuan Chen , Jiahe Chen , Hongxia Xu , Jimeng Sun , Jian Wu , Jintai Chen

Diffusion models have achieved remarkable success in the image and video generation tasks. Nevertheless, they often require a large amount of memory and time overhead during inference, due to the complex network architecture and…

计算机视觉与模式识别 · 计算机科学 2024-12-24 Haocheng Huang , Jiaxin Chen , Jinyang Guo , Ruiyi Zhan , Yunhong Wang

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…

图像与视频处理 · 电气工程与系统科学 2024-11-26 Yunxiang Li , Hua-Chieh Shao , Xiaoxue Qian , You Zhang

Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Electrocardiograms (ECGs) are the most widely used non-invasive tool for cardiac assessment, yet large, well-annotated ECG corpora are scarce due to cost, privacy, and…

机器学习 · 计算机科学 2025-11-14 Xiaoda Wang , Kaiqiao Han , Yuhao Xu , Xiao Luo , Yizhou Sun , Wei Wang , Carl Yang