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We aim to present a comprehensive overview of the latest advancements in utilizing Large Language Models (LLMs) within the healthcare sector, emphasizing their transformative impact across various medical domains. LLMs have become pivotal…

计算与语言 · 计算机科学 2026-04-07 Ummara Mumtaz , Awais Ahmed , Summaya Mumtaz

Process mining has emerged as a powerful analytical technique for understanding complex healthcare workflows. However, its application faces significant barriers, including technical complexity, a lack of standardized approaches, and…

人工智能 · 计算机科学 2026-02-11 Eduardo Illueca-Fernandez , Kaile Chen , Fernando Seoane , Farhad Abtahi

This study explores the explainability capabilities of large language models (LLMs), when employed to autonomously generate machine learning (ML) solutions. We examine two classification tasks: (i) a binary classification problem focused on…

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

人工智能 · 计算机科学 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

Large Language Models (LLMs) have shown remarkable success in supporting a wide range of knowledge-intensive tasks. In specialized domains, there is growing interest in leveraging LLMs to assist subject matter experts with domain-specific…

Drug discovery is a complex and resource-intensive process, making early prediction of approval outcomes critical for optimizing research investments. While classical machine learning and deep learning methods have shown promise in drug…

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

计算与语言 · 计算机科学 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

This systematic literature review comprehensively examines the application of Large Language Models (LLMs) in forecasting and anomaly detection, highlighting the current state of research, inherent challenges, and prospective future…

机器学习 · 计算机科学 2024-02-19 Jing Su , Chufeng Jiang , Xin Jin , Yuxin Qiao , Tingsong Xiao , Hongda Ma , Rong Wei , Zhi Jing , Jiajun Xu , Junhong Lin

The exponential growth of text-based data in domains such as healthcare, education, and social sciences has outpaced the capacity of traditional qualitative analysis methods, which are time-intensive and prone to subjectivity. Large…

This paper explores the significant impact of AI-based medical devices, including wearables, telemedicine, large language models, and digital twins, on clinical decision support systems. It emphasizes the importance of producing outcomes…

人工智能 · 计算机科学 2024-04-11 Elham Nasarian , Roohallah Alizadehsani , U. Rajendra Acharya , Kwok-Leung Tsui

One of the major barriers to using large language models (LLMs) in medicine is the perception they use uninterpretable methods to make clinical decisions that are inherently different from the cognitive processes of clinicians. In this…

计算与语言 · 计算机科学 2023-08-15 Thomas Savage , Ashwin Nayak , Robert Gallo , Ekanath Rangan , Jonathan H Chen

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

计算与语言 · 计算机科学 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

Large language models (LLMs) have demonstrated potential in the innovation of many disciplines. However, how they can best be developed for oncology remains underdeveloped. State-of-the-art OpenAI models were fine-tuned on a clinical…

人工智能 · 计算机科学 2024-06-17 Tristen Pool , Dennis Trujillo

Declarative specifications have a vital role to play in developing safe and dependable software systems. Writing specifications correctly, however, remains particularly challenging. This paper presents a controlled experiment on using large…

软件工程 · 计算机科学 2025-07-22 Yang Hong , Shan Jiang , Yulei Fu , Sarfraz Khurshid

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

计算与语言 · 计算机科学 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

人工智能 · 计算机科学 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Large Language Models (LLMs) are increasingly integrated into critical decision-making pipelines, a trend that raises the demand for robust and automated data analysis. Current approaches to dataset risk analysis are limited to manual…

人工智能 · 计算机科学 2026-05-28 Panteleimon Rodis

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

计算与语言 · 计算机科学 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

Large language models (LLMs) not only exhibit human-like performance but also share computational principles with the brain's language processing mechanisms. While prior research has focused on mapping LLMs' internal representations to…

计算与语言 · 计算机科学 2025-04-07 Maryam Rahimi , Yadollah Yaghoobzadeh , Mohammad Reza Daliri

Large language models (LLMs) have substantially advanced machine learning research, including natural language processing, computer vision, data mining, etc., yet they still exhibit critical limitations in explainability, reliability,…

机器学习 · 计算机科学 2025-09-19 Xin Wang , Haoyang Li , Haibo Chen , Zeyang Zhang , Wenwu Zhu