相关论文: HELM-BERT: A Transformer for Medium-sized Peptide …

Language models pre-trained on biomedical corpora, such as BioBERT, have recently shown promising results on downstream biomedical tasks. Many existing pre-trained models, on the other hand, are resource-intensive and computationally heavy…

Designing therapeutic peptides with tailored properties is hindered by the vastness of sequence space, limited experimental data, and poor interpretability of current generative models. To address these challenges, we introduce PepThink-R1,…

Social telehealth has made remarkable progress in healthcare by allowing patients to post symptoms and participate in medical consultations remotely. Users frequently post symptoms on social media and online health platforms, creating a…

We present a Three-level Hierarchical Transformer Network (3-level-HTN) for modeling long-term dependencies across clinical notes for the purpose of patient-level prediction. The network is equipped with three levels of Transformer-based…

Molecular property prediction is an increasingly critical task within drug discovery and development. Typically, neural networks can learn molecular properties using graph-based, language-based or feature-based methods. Recent advances in…

Less than 1% of protein sequences are structurally and functionally annotated. Natural Language Processing (NLP) community has recently embraced self-supervised learning as a powerful approach to learn representations from unlabeled text,…

The significant advancements in visual understanding and instruction following from Multimodal Large Language Models (MLLMs) have opened up more possibilities for broader applications in diverse and universal human-centric scenarios.…

Polymers are a vital part of everyday life. Their chemical universe is so large that it presents unprecedented opportunities as well as significant challenges to identify suitable application-specific candidates. We present a complete…

Current token-sequence-based Large Language Models (LLMs) are not well-suited for directly processing 3D Boundary Representation (Brep) models that contain complex geometric and topological information. We propose BrepLLM, the first…

Chemical language models (CLMs) are prominent for their effectiveness in exploring chemical space and enabling molecular engineering. However, while exploring chemical-linguistic space, CLMs suffer from the gap between natural language and…

Transformer architectures show significant promise for natural language processing. Given that a single pretrained model can be fine-tuned to perform well on many different tasks, these networks appear to extract generally useful linguistic…

Artificial intelligence (AI) is reshaping computational and network biology by enabling new approaches to decode cellular communication networks. We introduce Hierarchical Molecular Language Models (HMLMs), a novel framework that models…

In language processing, training data with extremely large variance may lead to difficulty in the language model's convergence. It is difficult for the network parameters to adapt sentences with largely varied semantics or grammatical…

Language Model pre-training uses broad data mixtures to enhance performance across domains and languages. However, training on such heterogeneous text corpora requires extensive and expensive efforts. Since these data sources vary…

Existing Self-Supervised Learning (SSL) models for speech typically process speech signals at a fixed resolution of 20 milliseconds. This approach overlooks the varying informational content present at different resolutions in speech…

Recent works show that learning contextualized embeddings for words is beneficial for downstream tasks. BERT is one successful example of this approach. It learns embeddings by solving two tasks, which are masked language model (masked LM)…

Large foundation models have achieved significant performance gains through scalable training on massive datasets. However, the field of \textbf{H}andwritten \textbf{M}athematical \textbf{E}xpression \textbf{R}ecognition (HMER) has been…

Bipolar disorder is a chronic mental illness frequently underdiagnosed due to subtle early symptoms and social stigma. This paper explores the advanced natural language processing (NLP) models for recognizing signs of bipolar disorder based…

Large Language Models (LLMs) like BERT have gained significant prominence due to their remarkable performance in various natural language processing tasks. However, they come with substantial computational and memory costs. Additionally,…

Large Language Models (LLMs) with their strong task-handling capabilities have shown remarkable advancements across a spectrum of fields, moving beyond natural language understanding. However, their proficiency within the chemistry domain…