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Deep learning-based segmentation techniques have shown remarkable performance in brain segmentation, yet their success hinges on the availability of extensive labeled training data. Acquiring such vast datasets, however, poses a significant…

计算机视觉与模式识别 · 计算机科学 2024-07-18 Jihoon Cho , Suhyun Ahn , Beomju Kim , Hyungjoon Bae , Xiaofeng Liu , Fangxu Xing , Kyungeun Lee , Georges Elfakhri , Van Wedeen , Jonghye Woo , Jinah Park

Bright-field microscopy, a cost-effective solution for live-cell culture, is often the only resource available, along with standard CPUs, for many low-budget labs. The inherent challenges of bright-field images -- their noisiness, low…

定量方法 · 定量生物学 2025-11-03 Surajit Das , Pavel Zun

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

定量方法 · 定量生物学 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and…

图像与视频处理 · 电气工程与系统科学 2020-05-20 Rituparna Sarkar , Suvadip Mukherjee , Elisabeth Labruyère , Jean-Christophe Olivo-Marin

Segmentation is a fundamental process in microscopic cell image analysis. With the advent of recent advances in deep learning, more accurate and high-throughput cell segmentation has become feasible. However, most existing deep…

计算机视觉与模式识别 · 计算机科学 2020-06-25 Hyeonsoo Lee , Won-Ki Jeong

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

图像与视频处理 · 电气工程与系统科学 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

图像与视频处理 · 电气工程与系统科学 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Microscopy enables direct observation of cellular morphology in 3D, with transmitted-light methods offering low-cost, minimally invasive imaging and fluorescence microscopy providing specificity and contrast. Virtual staining combines these…

Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Saqib Nazir , Ardhendu Behera

Accurate segmentation of multiple organs in Computed Tomography (CT) images plays a vital role in computer-aided diagnosis systems. While various supervised learning approaches have been proposed recently, these methods heavily depend on a…

计算机视觉与模式识别 · 计算机科学 2025-03-21 Yongzhi Huang , Fengjun Xi , Liyun Tu , Jinxin Zhu , Haseeb Hassan , Liyilei Su , Yun Peng , Jingyu Li , Jun Ma , Bingding Huang

Current biological and medical research is aimed at obtaining a detailed spatiotemporal map of a live cell's interior to describe and predict cell's physiological state. We present here an algorithm for complete 3-D modelling of cellular…

Light sheet fluorescence microscopy (LSM) enables high-resolution, three-dimensional (3D) imaging of biological specimens, providing rich volumetric data for studying cellular organization, pathology, and vascular networks. However, the…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Adina Scheinfeld , Haotan Zhang , Shang Mu , Rudolf L. M. van Herten , Lucas Stoffl , Ali Erturk , Zhuhao Wu , Johannes C. Paetzold

Hyperspectral image analysis has become an important topic widely researched by the remote sensing community. Classification and segmentation of such imagery help understand the underlying materials within a scanned scene, since…

计算机视觉与模式识别 · 计算机科学 2020-12-02 Jakub Nalepa , Michal Myller , Yasuteru Imai , Ken-ichi Honda , Tomomi Takeda , Marek Antoniak

Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

图像与视频处理 · 电气工程与系统科学 2022-11-29 Royden Wagner , Karl Rohr

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

图像与视频处理 · 电气工程与系统科学 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Deep neural networks have shown great success in representation learning. However, when learning with noisy labels (LNL), they can easily overfit and fail to generalize to new data. This paper introduces a simple and effective method, named…

计算机视觉与模式识别 · 计算机科学 2024-03-29 Yuyin Zhou , Xianhang Li , Fengze Liu , Qingyue Wei , Xuxi Chen , Lequan Yu , Cihang Xie , Matthew P. Lungren , Lei Xing

Feature foundation models - usually vision transformers - offer rich semantic descriptors of images, useful for downstream tasks such as (interactive) segmentation and object detection. For computational efficiency these descriptors are…

计算机视觉与模式识别 · 计算机科学 2025-09-01 Ronan Docherty , Antonis Vamvakeros , Samuel J. Cooper

Non-invasive morphological assessment is the cornerstone of oocyte and embryo selection in assisted reproductive technology, yet clinical practice remains limited by two-dimensional, qualitative microscopy. While three-dimensional (3D)…

Learning-based 3D shape segmentation is usually formulated as a semantic labeling problem, assuming that all parts of training shapes are annotated with a given set of tags. This assumption, however, is impractical for learning fine-grained…

计算机视觉与模式识别 · 计算机科学 2022-01-14 Xiaogang Wang , Xun Sun , Xinyu Cao , Kai Xu , Bin Zhou

The goal of our work is to perform pixel label semantic segmentation on 3D biomedical volumetric data. Manual annotation is always difficult for a large bio-medical dataset. So, we consider two cases where one dataset is fully labeled and…

计算机视觉与模式识别 · 计算机科学 2020-04-07 Shreya Roy , Anirban Chakraborty
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